相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Six Biophysical Screening Methods Miss a Large Proportion of Crystallographically Discovered Fragment Hits: A Case Study
Johannes Schiebel et al.
ACS CHEMICAL BIOLOGY (2016)
Infrared Laser Activation of Soluble and Membrane Protein Assemblies in the Gas Phase
Victor A. Mikhailov et al.
ANALYTICAL CHEMISTRY (2016)
Native State Mass Spectrometry, Surface Plasmon Resonance, and X-ray Crystallography Correlate Strongly as a Fragment Screening Combination
Lucy A. Woods et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Determining Membrane Protein-Lipid Binding Thermodynamics Using Native Mass Spectrometry
Xiao Cong et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Differential Mobility Spectrometry-Hydrogen Deuterium Exchange (DMS-HDX) as a Probe of Protein Conformation in Solution
Shaolong Zhu et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2016)
Revealing Higher Order Protein Structure Using Mass Spectrometry
Brian T. Chait et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2016)
Salt Bridge Rearrangement (SaBRe) Explains the Dissociation Behavior of Noncovalent Complexes
Rachel R. Ogorzalek Loo et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2016)
High-resolution mass spectrometry of small molecules bound to membrane proteins
Joseph Gault et al.
NATURE METHODS (2016)
Deconvolution Method for Specific and Nonspecific Binding of Ligand to Multiprotein Complex by Native Mass Spectrometry
Shenheng Guan et al.
ANALYTICAL CHEMISTRY (2015)
Mass Spectrometry of Protein Complexes: From Origins to Applications
Shahid Mehmood et al.
ANNUAL REVIEW OF PHYSICAL CHEMISTRY, VOL 66 (2015)
One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists
Johannes Schiebel et al.
CHEMMEDCHEM (2015)
Determination of thermodynamic and kinetic properties of biomolecules by mass spectrometry
Basri Guelbakan et al.
CURRENT OPINION IN BIOTECHNOLOGY (2015)
Probing allosteric mechanisms using native mass spectrometry
Michal Sharon et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2015)
Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90
Federico Riccardi Sirtori et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry
Michael B. Cammarata et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Probing Protein Structure and Folding in the Gas Phase by Electron Capture Dissociation
Moritz Schennach et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2015)
How Closely Related Are Conformations of Protein Ions Sampled by IM-MS to Native Solution Structures?
Shu-Hua Chen et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2015)
Electron transfer dissociation provides higher-order structural information of native and partially unfolded protein complexes
Frederik Lermyte et al.
PROTEOMICS (2015)
Time-Resolved Pulsed Hydrogen/Deuterium Exchange Mass Spectrometry Probes Gaseous Proteins Structural Kinetics
Khadijeh Rajabi
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2015)
Advances in coupling microfluidic chips to mass spectrometry
Xiaojun Feng et al.
MASS SPECTROMETRY REVIEWS (2015)
Large Scale Meta-Analysis of Fragment-Based Screening Campaigns: Privileged Fragments and Complementary Technologies
Peter S. Kutchukian et al.
JOURNAL OF BIOMOLECULAR SCREENING (2015)
Determination of Protein-Ligand Binding Constants of a Cooperatively Regulated Tetrameric Enzyme Using Electrospray Mass Spectrometry
Dragana Cubrilovic et al.
ACS CHEMICAL BIOLOGY (2014)
Proteins with Highly Similar Native Folds Can Show Vastly Dissimilar Folding Behavior When Desolvated
Moritz Schennach et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Revealing Ligand Binding Sites and Quantifying Subunit Variants of Noncovalent Protein Complexes in a Single Native Top-Down FTICR MS Experiment
Huilin Li et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2014)
Boundaries of Mass Resolution in Native Mass Spectrometry
Philip Lossl et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2014)
Ion mobility-mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility
Min Zhou et al.
NATURE CHEMISTRY (2014)
Plasmodium Gametocyte Inhibition Identified from a Natural-Product-Based Fragment Library
Hoan Vu et al.
ACS CHEMICAL BIOLOGY (2013)
Fragment Screening by Native State Mass Spectrometry
Sally-Ann Poulsen
AUSTRALIAN JOURNAL OF CHEMISTRY (2013)
Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism
Douglas Marcotte et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Native Biomolecules in the Gas Phase? The Case of Green Fluorescent Protein
Vladimir Frankevich et al.
CHEMPHYSCHEM (2013)
Native electrospray ionization and electron-capture dissociation for comparison of protein structure in solution and the gas phase
Hao Zhang et al.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2013)
Allosteric mechanisms can be distinguished using structural mass spectrometry
Andrey Dyachenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Fragmentation methods on the balance: unambiguous top-down mass spectrometric characterization of oxaliplatin-ubiquitin binding sites
Samuel M. Meier et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2012)
Site-Specific Analysis of Gas-Phase Hydrogen/Deuterium Exchange of Peptides and Proteins by Electron Transfer Dissociation
Kasper D. Rand et al.
ANALYTICAL CHEMISTRY (2012)
Automated Protein-Ligand Interaction Screening by Mass Spectrometry
Hannah J. Maple et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
How Ubiquitin Unfolds after Transfer into the Gas Phase
Owen S. Skinner et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
Improved Accuracy of Low Affinity Protein-Ligand Equilibrium Dissociation Constants Directly Determined by Electrospray Ionization Mass Spectrometry
Lucie Jaquillard et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
Do Charge State Signatures Guarantee Protein Conformations?
Zoe Hall et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
Reliable Determinations of Protein-Ligand Interactions by Direct ESI-MS Measurements. Are We There Yet?
Elena N. Kitova et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
Two decades of studying non-covalent biomolecular assemblies by means of electrospray ionization mass spectrometry
Gillian R. Hilton et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2012)
Native Electrospray and Electron-Capture Dissociation FTICR Mass Spectrometry for Top-Down Studies of Protein Assemblies
Hao Zhang et al.
ANALYTICAL CHEMISTRY (2011)
Electrostatic Stabilization of a Native Protein Structure in the Gas Phase
Kathrin Breuker et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Enzyme Closure and Nucleotide Binding Structurally Lock Guanylate Kinase
Olivier Delalande et al.
BIOPHYSICAL JOURNAL (2011)
Top-down mass spectrometry of supercharged native protein-ligand complexes
Sheng Yin et al.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2011)
Binding dynamics and energetic insight into the molecular forces driving nucleotide binding by guanylate kinase
Mahmoud Kandeel et al.
JOURNAL OF MOLECULAR RECOGNITION (2011)
Structural Stability from Solution to the Gas Phase: Native Solution Structure of Ubiquitin Survives Analysis in a Solvent-Free Ion Mobility-Mass Spectrometry Environment
Thomas Wyttenbach et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2011)
Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds
Gregory J. Crowther et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2011)
Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors
Nyssa Drinkwater et al.
BIOCHEMICAL JOURNAL (2010)
A Method for Removing Effects of Nonspecific Binding on the Distribution of Binding Stoichiometries: Application to Mass Spectroscopy Data
Liat Shimon et al.
BIOPHYSICAL JOURNAL (2010)
Native MS: an 'ESI' way to support structure- and fragment-based drug discovery
Valerie Vivat Hannah et al.
FUTURE MEDICINAL CHEMISTRY (2010)
Probing the Hydrophobic Effect of Noncovalent Complexes by Mass Spectrometry
Claudia Bich et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
Quantifying Labile Protein-Ligand Interactions Using Electrospray Ionization Mass Spectrometry
Amr El-Hawiet et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
Elucidating the Site of Protein-ATP Binding by Top-Down Mass Spectrometry
Sheng Yin et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
Affinity Classification of Kinase Inhibitors by Mass Spectrometric Methods and Validation Using Standard IC50 Measurements
Matthias Conradin Jecklin et al.
ANALYTICAL CHEMISTRY (2009)
Gas-Phase Hydrogen/Deuterium Exchange in a Traveling Wave Ion Guide for the Examination of Protein Conformations
Kasper D. Rand et al.
ANALYTICAL CHEMISTRY (2009)
Structural and Biophysical Characterization of XIAP BIR3 G306E Mutant: Insights in Protein Dynamics and Application for Fragment-Based Drug Design
Cathy D. Moore et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2009)
Lessons for fragment library design: analysis of output from multiple screening campaigns
I-Jen Chen et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2009)
Temperature-dependent cooperativity in donor-acceptor substrate binding to the human blood group glycosyltransferases
Glen K. Shoemaker et al.
GLYCOBIOLOGY (2008)
Mass spectrometry of protein-ligand complexes: Enhanced gas-phase stability of ribonuclease-nucleotide complexes
Sheng Yin et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2008)
Stepwise evolution of protein native structure with electrospray into the gas phase, 10-12 to 102 S
Kathrin Breuker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A combined transcriptome and proteome survey of malaria parasite liver stages
Alice S. Tarun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A novel approach to analyze membrane proteins by laser mass spectrometry: From protein subunits to the integral complex
Nina Morgner et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2007)
Estrogen receptor-ligand complexes measured by chip-based nanoelectrospray mass spectrometry: An approach for the screening of endocrine disruptors
Cedric Bovet et al.
PROTEIN SCIENCE (2007)
Top-down ESI-ECD-FT-ICR mass spectrometry localizes noncovalent protein-ligand binding sites
Yongming Xie et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
A deconvolution method for the separation of specific versus nonspecific interactions in noncovalent protein-ligand complexes analyzed by ESI-FT-ICR mass spectrometry
Thorsten Daubenfeld et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2006)
Direct screening of a dynamic combinatorial library using mass spectrometry
Sally-Ann Poulsen
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2006)
Applications of ESI-MS in drug discovery: interrogation of noncovalent complexes
Steven A. Hofstadler et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
A new way to detect noncovalently bonded complexes of biomolecules from liquid micro-droplets by laser mass spectrometry
N Morgner et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2006)
Evidence for unfolding and refolding of gas-phase cytochrome c ions in a Paul trap
ER Badman et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2005)
Recent developments in electrospray ionisation mass spectrometry: noncovalently bound protein complexes
AE Ashcroft
NATURAL PRODUCT REPORTS (2005)
The thermal unfolding of native cytochrome c in the transition from solution to gas phase probed by native electron capture dissociation
K Breuker et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Determination of protein-ligand association thermochemistry using variable-temperature nanoelectrospray mass spectrometry
R Daneshfar et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Structure-activity relationships by mass spectrometry: identification of novel MMP-3 inhibitors
DA Ockey et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2004)
Determination of dissociation constants for protein-ligand complexes by electrospray ionization mass spectrometry
A Tjernberg et al.
ANALYTICAL CHEMISTRY (2004)
The study of protein-ligand interactions by mass spectrometry - a personal view
K Breuker
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2004)
Features of the ESI mechanism that affect the observation of multiply charged noncovalent protein complexes and the determination of the association constant by the titration method
M Peschke et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2004)
Influence of solution and gas phase processes on protein-carbohydrate binding affinities determined by nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry
WJ Wang et al.
ANALYTICAL CHEMISTRY (2003)
Use of a microchip device coupled with mass spectrometry for ligand screening of a multi-protein target
CA Keetch et al.
ANALYTICAL CHEMISTRY (2003)
Entropy is the major driving force for fragmentation of proteins and protein-ligand complexes in the gas phase
J Laskin et al.
JOURNAL OF PHYSICAL CHEMISTRY A (2003)
Quantitative determination of noncovalent binding interactions using automated nanoelectrospray mass spectrometry
S Zhang et al.
ANALYTICAL CHEMISTRY (2003)
Automated nano-electrospray mass spectrometry for protein-ligand screening by noncovalent interaction applied to human H-FABP and A-FABP
K Benkestock et al.
JOURNAL OF BIOMOLECULAR SCREENING (2003)
Gas phase hydrogen/deuterium exchange of proteins in an ion trap mass spectrometer
SE Evans et al.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2003)
Electrospray wings for molecular elephants (Nobel lecture)
JB Fenn
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Native electron capture dissociation for the structural characterization of noncovalent interactions in native cytochrome c
K Breuker et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Structural transitions of electrosprayed ubiquitin ions stored in an ion trap over ∼10 ms to 30 s
S Myung et al.
JOURNAL OF PHYSICAL CHEMISTRY A (2002)
SAR by MS: A ligand based technique for drug lead discovery against structured RNA targets
EE Swayze et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Detailed unfolding and folding of gaseous ubiquitin ions characterized by electron capture dissociation
K Breuker et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Kinetic intermediates in the folding of gaseous protein ions characterized by electron capture dissociation mass spectrometry
DM Horn et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
分享论文
