Progress in Synthetic Trends Followed for the Development of 1,2,3-Triazole Derivatives: A Review

Since the beginning of click chemistry, 1,2,3-triazoles has been at the center of modern organic chemistry. This versatile framework has found broad applications in organic synthesis, drug discovery, chemical biology, polymer chemistry, supramolecular chemistry, bioconjugation, fluorescent imaging, and materials sciences. Due to tremendous use of 1,2,3-triazoles in chemistry, synthesis of this moiety from the easily available chemicals is desirable. This review covers different conventional and non-conventional approaches adopted for the synthesis of 1,2,3-triazole derivatives.

Automated summary

Since the beginning of click chemistry, 1,2,3-triazoles has been widely used in various fields of chemistry, such as organic synthesis, drug discovery, chemical biology, polymer chemistry, supramolecular chemistry, bioconjugation, fluorescent imaging, and materials sciences. Therefore, the synthesis of 1,2,3-triazole derivatives from readily available chemicals is of great importance. This review provides an overview of different conventional and non-conventional approaches adopted for the synthesis of 1,2,3-triazole derivatives.