4.5 Article

LPCAT1 levels in the placenta, the maternal plasma and the fetal plasma do not predict fetal lung responses to glucocorticoids in a sheep model of pregnancy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Obstetrics & Gynecology

Lysophosphatidylcholine acyltransferase 1 protein is present in maternal blood in the third trimester and is upregulated by antenatal corticosteroids

Katherine J. Kramer et al.

Summary: This study aimed to detect the presence of LPCAT1 protein in maternal plasma and assess the impact of antenatal corticosteroids. The results showed that LPCAT1 protein could be measured in maternal plasma after 32 weeks gestation, and there was an increase in maternal plasma LPCAT1 levels after the clinical administration of antenatal corticosteroids.

JOURNAL OF PERINATAL MEDICINE (2023)

Article Obstetrics & Gynecology

Betamethasone phosphate reduces the efficacy of antenatal steroid therapy and is associated with lower birthweights when administered to pregnant sheep in combination with betamethasone acetate

Tsukasa Takahashi et al.

Summary: Antenatal corticosteroid therapy is effective for preventing preterm labor, but the optimal dosing strategy is unclear. A study using a sheep model found that low-dosage betamethasone acetate alone is sufficient for fetal lung maturation.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2022)

Article Developmental Biology

Molecular mechanisms regulating lysophosphatidylcholine acyltransferase 1 (LPCAT1) in human pregnancy

Neeraja Purandare et al.

Summary: The study shows that LPCAT1 protein levels peak in late third trimester placental samples, with strong expression on the basal plate. Moreover, LPCAT1 is transcriptionally activated by the bi-organellar regulator MNRR1, and antenatal corticosteroids upregulate LPCAT1 in a MNRR1-dependent manner.

PLACENTA (2021)

Review Physiology

Phospholipid Remodeling in Physiology and Disease

Bo Wang et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 81 (2019)

Article Obstetrics & Gynecology

Maternal plasma LPCAT 1 mRNA correlates with lamellar body count

Robert A. Welch et al.

JOURNAL OF PERINATAL MEDICINE (2018)

Review Cell Biology

MNRR1, a Biorganellar Regulator of Mitochondria

Lawrence I. Grossman et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)

Article Medicine, General & Internal

Antenatal Betamethasone for Women at Risk for Late Preterm Delivery

C. Gyamfi-Bannerman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Medicine, General & Internal

Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012

Barbara J. Stoll et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)

Review Biochemistry & Molecular Biology

Structure-function relationships in pulmonary surfactant membranes: From biophysics to therapy

Elena Lopez-Rodriguez et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)

Article Biochemistry & Molecular Biology

Phosphatidylcholine formation by LPCAT1 is regulated by Ca2+ and the redox status of the cell

Eric Soupene et al.

BMC BIOCHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Cross-talk between Remodeling and de Novo Pathways Maintains Phospholipid Balance through Ubiquitination

Phillip L. Butler et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Medicine, Research & Experimental

LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice

James P. Bridges et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Biochemistry & Molecular Biology

Biosynthesis of phosphatidylcholine by human lysophosphatidylcholine acyltransferase 1

Takeshi Harayama et al.

JOURNAL OF LIPID RESEARCH (2009)

Article Obstetrics & Gynecology

The Probability of Neonatal Respiratory Distress Syndrome as a Function of Gestational Age and Lecithin/Sphingomyelin Ratio

Caryn St. Clair et al.

AMERICAN JOURNAL OF PERINATOLOGY (2008)

Article Reproductive Biology

The pregnant sheep as a model for human pregnancy

J. S. Barry et al.

THERIOGENOLOGY (2008)

Article Multidisciplinary Sciences

Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes

Eric Soupene et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells

Xueni Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Obstetrics & Gynecology

Differential effects of maternal betamethasone and cortisol on lung maturation and growth in fetal sheep

AH Jobe et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2003)

Article Biochemistry & Molecular Biology

Surfactant in respiratory distress syndrome and lung injury

M Hallman et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY (2001)

Article Critical Care Medicine

Endotoxin-induced lung maturation in preterm lambs is not mediated by cortisol

AH Jobe et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)