4.5 Article

Microalgal nutraceuticals: unravelling solution to food-health nexus

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Environmental Studies

Exploring future research and innovation directions for a sustainable blue economy

Lisa A. Pace et al.

Summary: This study explores the role of foresight in co-creating alternative futures for a sustainable blue economy and establishing an interdisciplinary dialogue. By conducting a foresight exercise with marine scientists and researchers in 6 European countries, it is found that foresight can bridge across disciplinary perspectives and industry sectors.

MARINE POLICY (2023)

Review Biotechnology & Applied Microbiology

Transformation of Agro-Waste into Value-Added Bioproducts and Bioactive Compounds: Micro/Nano Formulations and Application in the Agri-Food-Pharma Sector

Saroj Bala et al.

Summary: The agricultural sector produces a significant amount of waste, most of which is not effectively used and poses a danger to global health and the environment. Valorization techniques are employed to convert agro-wastes into various bioproducts and biologically active molecules, which are of great relevance in the agri-food-pharma sectors. This review discusses different methods of agro-waste valorization, value-added bioproducts, recovery of bioactive compounds, and their applications, as well as the current status of bioactive micro- and nanoencapsulation strategies.

BIOENGINEERING-BASEL (2023)

Review Agricultural Engineering

Biological active metabolites from microalgae for healthcare and pharmaceutical industries: A comprehensive review

Tengku Nilam Baizura Tengku Ibrahim et al.

Summary: This review summarizes microalgae species capable of producing metabolites and comprehensively discusses the potential applications of these metabolites in the healthcare and pharmaceutical industries. It greatly assists industrial stakeholders, investors, and researchers in making business decisions, investing in ventures, and advancing the production of microalgae-based metabolites.

BIORESOURCE TECHNOLOGY (2023)

Review Chemistry, Medicinal

Astaxanthin as a King of Ketocarotenoids: Structure, Synthesis, Accumulation, Bioavailability and Antioxidant Properties

Anagha Nair et al.

Summary: Natural astaxanthin is richer than synthetic astaxanthin, but cultivating it in photobioreactors is expensive and downstream processing techniques for solubilization are not cost-effective. As a result, the cost of astaxanthin is high, leading pharmaceutical and nutraceutical companies to opt for synthetic astaxanthin. This review discusses the chemical character of astaxanthin, more cost-effective cultivating techniques, and its bioavailability. Moreover, the antioxidant properties of this microalgal product against various diseases are discussed, which make it a promising drug for reducing inflammation and its consequences.

MARINE DRUGS (2023)

Article Green & Sustainable Science & Technology

Ecosystem services and climate action from a circular bioeconomy perspective

Rozi Sharma et al.

Summary: Although oil, gas, and coal resources may become unavailable by certain years in the future, the majority of energy production still relies on fossil fuels, which is considered unsustainable and harmful to the environment. Climate change and biodiversity loss have posed significant risks to humanity, thus policymakers have recommended transitioning to a bio-based economy to mitigate these risks. The circular bioeconomy is seen as an effective approach to utilize ecosystem services for sustainable socio-ecological development and address national and international challenges caused by climate action.

RENEWABLE & SUSTAINABLE ENERGY REVIEWS (2023)

Review Food Science & Technology

Bioprocessing to Preserve and Improve Microalgae Nutritional and Functional Potential: Novel Insight and Perspectives

Michela Verni et al.

Summary: Microalgae are unicellular microorganisms that live in aquatic environments. They have various nutritional and functional properties, including antioxidant, immunomodulatory, and anticancer effects. Although microalgae have high protein content, their use as food is often hindered by unpleasant color and flavor. Different strategies, such as extraction and fermentation, have been proposed to overcome these challenges, but more research is needed to find cost-effective pre-treatments that can utilize the whole biomass and enhance the overall nutritional value.
Review Energy & Fuels

Third-generation biorefineries: a sustainable platform for food, clean energy, and nutraceuticals production

Latika Bhatia et al.

Summary: This article discusses the technical developments, industrial scenario, environmental issues, and range of diversified products from third-generation biorefineries, specifically focusing on the exploration of algal biomass into fuels and biochemicals through multidisciplinary technological routes.

BIOMASS CONVERSION AND BIOREFINERY (2022)

Review Medicine, Research & Experimental

Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases

Zeynab Kohandel et al.

Summary: This study summarizes the anti-inflammatory efficacy of astaxanthin in various chronic and acute disorders, as well as the pathways through which it mediates its effects. Further experimental and clinical studies are needed to confirm the anti-inflammatory and protective effects of astaxanthin in humans. The review suggests that astaxanthin, with its demonstrated anti-inflammatory properties, may be a suitable candidate for drug design with novel technology.

BIOMEDICINE & PHARMACOTHERAPY (2022)

Review Agricultural Engineering

Design and applications of photobioreactors- a review

Ranjna Sirohi et al.

Summary: There has been increasing attention on the use of photobioreactors for microalgae cultivation. Understanding the state-of-the-art designs, advantages, and limitations is crucial for classifying and applying different photobioreactors effectively.

BIORESOURCE TECHNOLOGY (2022)

Article Agricultural Engineering

Mass cultivation and harvesting of microalgal biomass: Current trends and future perspectives

Aswathy Udayan et al.

Summary: Microalgae are unicellular photosynthetic organisms that can produce high-value metabolites, making them potential candidates for nutraceutical and industrial products. Research on cost-effective cultivation systems and harvesting methods is crucial for increasing biomass yield and reducing downstream processing costs to fully utilize the potential of microalgae in industry.

BIORESOURCE TECHNOLOGY (2022)

Article Pharmacology & Pharmacy

Astaxanthin extenuates the inhibition of aldehyde dehydrogenase and Klotho protein expression in cyclophosphamide-induced acute cardiomyopathic rat model

Somow S. Kamel et al.

Summary: The study evaluated the mechanistic sequel of ALDH2 and Klotho protein in CP-induced cardiotoxicity in rats and the protective effect of AST. Results showed that CP increased cardiotoxicity indices and caused histopathological lesions in cardiac tissues, while AST reversed these changes. Inhibition of ALDH2, Klotho protein, mTOR, and AMPK signals might contribute to CP-induced acute cardiomyopathy, which was attenuated by AST supplementation by modulating ALDH2 and Klotho protein expression in heart tissues.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2022)

Article Thermodynamics

Assessment and multi-objective optimization of a vanadium-chlorine thermochemical cycle integrated with algal biomass gasification for hydrogen and power production

Farid Safari et al.

Summary: A cogeneration system for green hydrogen and power production using algal biomass and water has been developed, optimized for higher exergy efficiency, lower cost, and lower environmental impact. The system incorporates a V-Cl thermochemical cycle for hydrogen production, with a novel integration proposed in this study. Performance evaluation and validation have been conducted, resulting in optimal values for overall exergy efficiency, total cost per unit of exergy, and environmental impacts.

ENERGY CONVERSION AND MANAGEMENT (2022)

Article Energy & Fuels

Microalgae biomass as a sustainable source for biofuel, biochemical and biobased value-added products: An integrated biorefinery concept

Sk Yasir Arafat Siddiki et al.

Summary: Microalgae biomass has been proven to be a sustainable source for biofuels such as bio-oil, biodiesel, bioethanol, biomethane, etc. The integration of microalgal technologies in industry has the added benefit of capturing carbon dioxide and reducing emissions. While industrial microalgae applications face challenges of energy and cost, utilizing a bio-refinery approach to extract components from microalgae could be a solution. Suitable microalgae species are crucial for high-quality biofuel and value-added products production, with potential applications in various industries such as agriculture, animal husbandry, medicine, culinary, and cosmetics.
Article Chemistry, Physical

Supercritical fluid extraction of lipids rich in DHA from Schizochytrium sp

Melissa Rodriguez-Espana et al.

Summary: The study found that supercritical fluid extraction combined with pretreatment can extract high lipid yields and DHA concentrations in shorter extraction times.

JOURNAL OF SUPERCRITICAL FLUIDS (2022)

Review Plant Sciences

The role of photosynthesis related pigments in light harvesting, photoprotection and enhancement of photosynthetic yield in planta

Andrew J. Simkin et al.

Summary: Photosynthetic pigments, including chlorophyll, carotenoids, and phycobilins, are essential for efficient light absorption and adaptation to different environments in photosynthetic organisms. They play crucial roles in light harvesting, photoprotection, and deep water colonization.

PHOTOSYNTHESIS RESEARCH (2022)

Article Green & Sustainable Science & Technology

Continuous cultivation of microalgae in photobioreactors as a source of renewable energy: Current status and future challenges

Angela Paul Peter et al.

Summary: Microalgae are promising sustainable energy sources for biodiesel production due to their rapid photosynthesis growth rate and ability to be cultivated in various water sources. The utilization of photosynthesis reactions by microalgae allows for the conversion of light energy into renewable energy, while closed photobioreactors provide resistance to contamination and enable monitoring of environmental factors.

RENEWABLE & SUSTAINABLE ENERGY REVIEWS (2022)

Article Chemistry, Multidisciplinary

Biomolecules from Microalgae and Cyanobacteria: Applications and Market Survey

Rihab Hachicha et al.

Summary: Microalgae and cyanobacteria are promising and sustainable sources of valuable bioactive metabolites. This review focuses on their classification, taxonomic diversity, and ecological niches. It also summarizes the methods of cultivating and extracting high-value bioactive compounds from these microorganisms using open ponds and photobioreactors. Furthermore, it reviews the various commercial applications of microalgae and cyanobacteria in fields such as food, dietary supplements, feed, cosmetics, and biofuels.

APPLIED SCIENCES-BASEL (2022)

Review Environmental Sciences

Novel Bioactive Compounds From Marine Sources as a Tool for Functional Food Development

Susmita Ghosh et al.

Summary: The marine environment is rich in functional ingredients that can be used in various aspects of food processing. Marine microorganisms have the potential to produce novel bioactive chemicals that can be utilized in different industries. Many marine microorganisms have been found to produce antioxidant, antibacterial, apoptotic, antitumoral, and antiviral chemicals. The review focuses on the potential use of marine-derived chemicals as functional food ingredients for health maintenance and chronic disease prevention.

FRONTIERS IN MARINE SCIENCE (2022)

Article Chemistry, Medicinal

Antioxidant effects of astaxanthin and metformin combined therapy in type 2 diabetes mellitus patients: a randomized double-blind controlled clinical trial

Nikoo Roustaei Rad et al.

Summary: The study demonstrates that AST supplementation in combination with metformin has a synergistic effect in controlling oxidative stress in T2DM patients. This combination therapy improves antioxidant capacity by inducing Nrf2 transcription factor and activating SOD and catalase. Consequently, AST and metformin together may be beneficial in modifying oxidative stress and preventing T2DM complications.

RESEARCH IN PHARMACEUTICAL SCIENCES (2022)

Article Biochemistry & Molecular Biology

Astaxanthin Attenuates Adiponectin, Calprotectin, miRNA222 and miRNA378 in Obesity induced by High-Fat Diet in Rats

Sylvia A. Boshra

Summary: This study investigated the effects of astaxanthin and metformin on obesity induced by a high-fat diet in rats by measuring miRNA222 and 378. The results showed that both astaxanthin and metformin had anti-obesity and antioxidant effects, significantly reducing body weight, glucose, insulin, triglycerides, total cholesterol, and leptin levels, while increasing HDL-C and adiponectin levels. Furthermore, astaxanthin regulated the aberrant expression of miRNA222 and 378, which may be related to hyperlipidemia and insulin resistance.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2022)

Review Agricultural Engineering

A review on mechanical-based microalgae harvesting methods for biofuel production

Mahyar Ghazvini et al.

Summary: Microalgae have great potential as a feedstock for biofuel production, but the high cost of harvesting makes their utilization economically unfeasible. Mechanical-based harvesting methods, such as centrifugation and filtration, are considered effective means of microalgae recovery, but they differ in terms of cost and efficiency. Centrifugation offers the highest cell removal efficiency but comes with the highest capital and operational costs, while sedimentation is relatively inexpensive and widely applicable. However, flotation needs to be combined with filtration, and may not be suitable for all algal cultures.

BIOMASS & BIOENERGY (2022)

Article Agricultural Engineering

Techno-economic modeling to produce biodiesel from marine microalgae in sub-Saharan countries: An exploratory study in Guinea-Bissau

Tito Francisco Ianda et al.

Summary: This research examines the feasibility of microalgae biodiesel production in Guinea-Bissau through technoeconomic analysis. The simulations show that the cost of producing microalgae biodiesel is competitive and has potential for scaling up.

BIOMASS & BIOENERGY (2022)

Article Agricultural Engineering

Research trends and market opportunities of microalgal biorefinery technologies from circular bioeconomy perspectives

Bunushree Behera et al.

Summary: This study utilizes scientometric analysis to examine the research trends and collaborations in microalgae biorefinery, highlighting the importance of international cooperation and synergistic integration of unit processes for the feasibility of microalgae-based bio-products.

BIORESOURCE TECHNOLOGY (2022)

Article Endocrinology & Metabolism

Associations of Serum Carotenoids With Risk of Cardiovascular Mortality Among Individuals With Type 2 Diabetes: Results From NHANES

Zixin Qiu et al.

Summary: Higher serum concentrations of beta-carotene, but not other individual carotenoids, are significantly associated with an increased risk of cardiovascular mortality among individuals with type 2 diabetes (T2D).

DIABETES CARE (2022)

Review Environmental Sciences

Microalgae-based bioplastics: Future solution towards mitigation of plastic wastes

Jun Wei Roy Chong et al.

Summary: This article introduces a sustainable and environmentally friendly approach to producing bioplastics using microalgae as a feed source, including the production of PHA from microalgae biomass, the use of microalgae biomass as fillers and reinforcements for modifying bioplastics, and the intermediate processing of bioplastics using lactic acid synthesized from microalgae.

ENVIRONMENTAL RESEARCH (2022)

Review Energy & Fuels

Advancement and role of abiotic stresses in microalgae biorefinery with a focus on lipid production

Farhana Bibi et al.

Summary: Microalgae have been identified as a promising alternative feedstock for carbon-neutral biofuel production. This study aims to explore the effects of various abiotic stresses on microalgal biofuel production and review strategies to induce lipid production in microalgae. The manipulation of abiotic growth factors has been shown to facilitate high lipid and biomass accumulation in microalgae cultivation. The commercialization of algae-based biofuels through cost-effective and multi-product generation routes remains valid in the context of global decarbonization movement.
Article Energy & Fuels

Production and harvesting of microalgae and an efficient operational approach to biofuel production for a sustainable environment

Shamshad Khan et al.

Summary: Biofuel derived from microalgae has become an environmentally friendly alternative to conventional fossil fuels, but there are still technical and economic challenges in mass production and harvesting. This review discusses the difficulties in establishing an integrated system for large-scale microalgal production and harvesting, as well as the advancements in harvesting methods and opportunities for genetic engineering.
Review Green & Sustainable Science & Technology

Trends and advances in sustainable bioethanol production by marine microalgae: A critical review

Sudatta Maity et al.

Summary: Due to rapid urbanization and motorization, the global demand for petroleum oil is obstinately increasing, raising concerns for alternative sustainable fuels. Marine microalgae, as third-generation feedstock, have gained attention for bioethanol production, thanks to their abundant resources, ability to grow in nonpotable seawater, and unique metabolites. However, research on marine-based bioethanol production is still in its infancy.

JOURNAL OF CLEANER PRODUCTION (2022)

Review Chemistry, Medicinal

Bioactive Peptides from Algae: Traditional and Novel Generation Strategies, Structure-Function Relationships, and Bioinformatics as Predictive Tools for Bioactivity

Jack O'Connor et al.

Summary: This review focuses on the emerging processes for the extraction and isolation of bioactive peptides from algae, summarizing their biological properties, mechanisms of action, and challenges and opportunities for identifying specific peptides of interest.

MARINE DRUGS (2022)

Review Environmental Sciences

Emerging microalgae-based technologies in biorefinery and risk assessment issues: Bioeconomy for sustainable development

Pooja Sharma et al.

Summary: Industrial wastewater treatment is crucial for the safety of aquatic ecosystems and the health of humans living near water bodies. Microalgae-based technologies not only efficiently remove environmental pollutants but also produce a wide range of healthy supplements, supporting the concept of biorefinery.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

Review Chemistry, Multidisciplinary

Microalgal Proteins and Bioactives for Food, Feed, and Other Applications

Simona Lucakova et al.

Summary: This review paper provides an overview of the current production of microalgae worldwide. It discusses the potential uses of microalgae in various industries such as feed, cosmetics, and functional foods. The paper also highlights the health benefits of microalgal proteins, lipids, vitamins, and minerals, and explores the potential impact of microalgae on global food and feed supply.

APPLIED SCIENCES-BASEL (2022)

Review Energy & Fuels

Biorefinery potential of Coelastrella biomass for fuel and bioproducts-a review

K. Nayana et al.

Summary: This review discusses the importance and potential of Coelastrella sp. in biorefinery techniques. Coelastrella sp. is capable of producing high-value compounds such as lipids and carotenoids, which can be used in fields such as biofuel and bioremediation.

BIOMASS CONVERSION AND BIOREFINERY (2022)

Article Biology

Microalgae Peptide-Stabilized Gold Nanoparticles as a Versatile Material for Biomedical Applications

Marielys Torres-Diaz et al.

Summary: This study investigates the use of gold nanoparticles as carriers for microalgae peptides and discusses their potential as stabilizing agents to improve the colloidal stability of the nanoparticles. The results show that the stability of the microalgae peptide increased when immobilized into the gold nanoparticles, and the modified nanoparticles exhibited lower toxicity and better viability compared to regular gold nanoparticles.

LIFE-BASEL (2022)

Article Microbiology

Characterization of novel euryhaline microalgal cultures from Punjab, India for bioactive compounds

Diksha Garg et al.

Summary: Microalgae have the potential to be a sustainable substitute for organic chemical-based health supplements due to their nutraceutical properties. Two microalgal strains, BGLR8 and BGLR16, from water-logged areas of Punjab, India, were evaluated for biomass production and characterization of nutraceutical properties. BGLR8 was found to have superior nutraceutical properties compared to BGLR16.

ARCHIVES OF MICROBIOLOGY (2022)

Review Biochemistry & Molecular Biology

Cyanobacteria: miniature factories for green synthesis of metallic nanomaterials: a review

Shraddha Pandey et al.

Summary: Nanotechnology is an advanced and promising field that focuses on the synthesis, characterization, and application of various nanomaterials. The use of biological resources, such as cyanobacteria, for green synthesis has emerged as a cost-effective and eco-friendly alternative to traditional methods. Cyanobacteria have shown to be favorable bioresources due to their ability to survive in diverse environments and tolerate high levels of metals. Through bioreduction, metallic nanomaterials can be synthesized using various capping agents present in the biological systems. These nanomaterials have found extensive applications in antimicrobial, anticancer, imaging, antifungal, catalytic, and bioremediation fields.

BIOMETALS (2022)

Article Agricultural Engineering

Performance of an immobilized microalgae-based process for wastewater treatment and biomass production: Nutrients removal, lipid induction, microalgae harvesting and dewatering

Song Cao et al.

Summary: Immobilized microalgae are effective for wastewater treatment and biomass production. This study investigated the efficiency of a continuously operated immobilized microalgae system for treating secondary effluent of wastewater treatment plants, as well as the methods for inducing valuable products and harvesting and dewatering microalgae biomass. The results showed a significant increase in microalgal dry weight and removal rates of ammonia and phosphate under suitable operating conditions.

BIORESOURCE TECHNOLOGY (2022)

Review Chemistry, Multidisciplinary

Algal biomass valorization for biofuel production and carbon sequestration: a review

Asma Sarwer et al.

Summary: The depletion of fossil fuels and the continuous increase in carbon dioxide concentrations have led to an energy crisis and environmental issues globally. Microalgal biofuels, produced using sunlight, water, and simple salt minerals, have the potential to be a key solution. Microalgae's high growth rate, photosynthesis, and ability to sequester carbon dioxide make them important biorefinery platforms. Additionally, their ability to produce high-value compounds under environmental stresses makes them a promising alternative to fossil fuels.

ENVIRONMENTAL CHEMISTRY LETTERS (2022)

Review Food Science & Technology

Microalgae as a sustainable source of edible proteins and bioactive peptides-Current trends and future prospects

Raman Kumar et al.

Summary: The global demand for protein ingredients is increasing, and sustainable alternative protein sources need to be identified. Microalgae have been advocated as a potential industrial source of edible proteins due to their wide and excellent ecological adaptation. However, the digestibility and application of microalgae proteins face challenges.

FOOD RESEARCH INTERNATIONAL (2022)

Article Biotechnology & Applied Microbiology

Green bioprocessing and applications of microalgae-derived biopolymers as a renewable feedstock: Circular bioeconomy approach

Anwesha Khanra et al.

Summary: This review presents an innovative approach to using microalgae for the production of biopolymers, aiming to achieve sustainable development in the global circular bioeconomy. It proposes a novel multi-phasic fed batch light depleted low-cost wastewater cultivation method to accelerate biopolymer production and provides a comprehensive summary of microalgae strains and extraction techniques for biopolymer synthesis. The review also addresses the challenges and future directions in microalgae cultivation, as well as the applications of microalgae-derived biopolymers in industrial and nutraceutical sectors.

ENVIRONMENTAL TECHNOLOGY & INNOVATION (2022)

Review Chemistry, Medicinal

Fucoxanthin Production of Microalgae under Different Culture Factors: A Systematic Review

Yam Sim Khaw et al.

Summary: This study systematically reviews the production of fucoxanthin in microalgae under different conditions. Microalgae are found to be a more reliable source of fucoxanthin compared to macroalgae, with higher fucoxanthin content achievable by adjusting the light intensity. The findings and recommendations from this study provide insights into the feasibility of commercial fucoxanthin production.

MARINE DRUGS (2022)

Article Biochemistry & Molecular Biology

Formation of Lutein, β-Carotene and Astaxanthin in a Coelastrella sp. Isolate

Hamdy Elsayed Ahmed Ali et al.

Summary: This study investigated the effect of media composition, N/P ratio, and cultivation strategy on carotenoid formation in a Coelastrella sp. isolate. The results suggest that Coelastrella sp. could be a promising feedstock for biodiesel production, as it can produce high levels of carotenoids under specific conditions.

MOLECULES (2022)

Review Green & Sustainable Science & Technology

Development of animal/plant-based protein hydrolysate and its application in food, feed and nutraceutical industries: State of the art

Yasaman Etemadian et al.

Summary: The optimal use of animal by-products has a direct impact on environmental pollution and economy, with by-products from aquatic, livestock, and poultry processing having potential for higher value products. Compliance with regulatory requirements, traditions, and community culture is crucial for ensuring the safety and quality of food when using livestock by-products for food production.

JOURNAL OF CLEANER PRODUCTION (2021)

Article Virology

Impaired glucose metabolism in patients with diabetes, prediabetes, and obesity is associated with severe COVID-19

Stephen M. Smith et al.

Summary: The study analyzed clinical characteristics associated with severe COVID-19 in 184 hospitalized patients in Livingston, New Jersey, and found that diabetes was common among COVID-19 patients and severe disease was often accompanied by impaired glucose metabolism.

JOURNAL OF MEDICAL VIROLOGY (2021)

Review Pharmacology & Pharmacy

Redox regulation by carotenoids: Evidence and conflicts for their application in cancer

Gian Luigi Russo et al.

Summary: Carotenoids, a class of compounds with important roles in foods, have been widely studied for their potential anticancer activity, but research results in this area vary; the dual nature of carotenoids acting as both antioxidants and pro-oxidants complicates mechanistic studies.

BIOCHEMICAL PHARMACOLOGY (2021)

Review Agricultural Engineering

Using green alga Haematococcus pluvialis for astaxanthin and lipid co-production: Advances and outlook

Yuanyua Ren et al.

Summary: Astaxanthin, an important antioxidant and nutraceutical compound, is widely used in dietary supplements and cosmetics. The refinery of astaxanthin from Haematococcus pluvialis is a growing industrial sector, as it can accumulate astaxanthin up to 5% of dry weight. Further research on production optimization and joint-production with lipids could make algal-derived astaxanthin more accessible for various applications.

BIORESOURCE TECHNOLOGY (2021)

Review Food Science & Technology

Supercritical fluid extraction (SCFE) as green extraction technology for high-value metabolites of algae, its potential trends in food and human health

Smita Singh et al.

Summary: The application of high-value algal metabolites (HVAMs) in various industries is crucial, and the use of green extraction technologies for obtaining these metabolites has become increasingly significant. This review focuses on supercritical fluid extraction (SCFE) as a principal green extraction technology for HVAM extraction, providing insights into HVAMs and the properties of SCFE technology.

FOOD RESEARCH INTERNATIONAL (2021)

Review Pharmacology & Pharmacy

Omega-3 polyunsaturated fatty acids focusing on eicosapentaenoic acid and docosahexaenoic acid in the prevention of cardiovascular diseases: a review of the state-of-the-art

Yasuhiro Watanabe et al.

Summary: This article reviews the roles of omega-3 polyunsaturated fatty acids in cardiovascular diseases, including their anti-inflammatory effects and specialized preparations for treatment. Various trials on the cardiovascular protective effects of omega-3 PUFAs have reported inconsistent results, possibly due to dosage and trial design issues.

EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2021)

Review Engineering, Chemical

Microalgae Biomolecules: Extraction, Separation and Purification Methods

Priscila S. Correa et al.

Summary: Microalgae have great biotechnological potential for producing a variety of biomolecules for industrial applications, but the challenge lies in making the processes economically viable and developing efficient technologies for extraction, recovery, and purification of valuable compounds accumulated inside the cells. Recent advancements focus on sustainable and scalable technologies, such as physicochemical treatments and solvent-free processes, to obtain target products from microalgae with high efficiency and purity, in line with the global shift towards bio-based products.

PROCESSES (2021)

Review Biotechnology & Applied Microbiology

Insights into phenolic compounds from microalgae: structural variety and complex beneficial activities from health to nutraceutics

Angelo Del Mondo et al.

Summary: Microalgae are photosynthetic organisms with high levels of biological and functional diversities, being recognized as promising sources for bioactive metabolites such as phenolic compounds. Despite being less investigated, microalgal phenolic compounds are considered an important natural source of bioactive molecules.

CRITICAL REVIEWS IN BIOTECHNOLOGY (2021)

Article Chemistry, Medicinal

Microalgal Peloids for Cosmetic and Wellness Uses

M. Lourdes Mourelle et al.

Summary: Peloids have been used for therapeutic purposes for a long time, mainly in the treatment of locomotor system pathologies and dermatology. Their effects are attributed to their components such as mineral waters, clays, microalgae, cyanobacteria, and other biological organisms. Research shows that peloids have potential as soothing, regenerating, antioxidant, anti-inflammatory, and antimicrobial agents in skincare.

MARINE DRUGS (2021)

Review Chemistry, Medicinal

Antioxidant Compounds from Microalgae: A Review

Noemie Coulombier et al.

Summary: The demand for natural products isolated from microalgae has increased in the past decade, especially natural antioxidants as an alternative to synthetic ones. Microalgae possess various advantages for biotechnological applications, including high biodiversity, photosynthetic yield, growth, productivity, and metabolic plasticity. This review aims to cover the diversity of antioxidant compounds, their mode of action, as well as various assays used to assess antioxidant activity in microalgae, in order to improve the selection of suitable assays for evaluating microalgae antioxidant activity.

MARINE DRUGS (2021)

Article Energy & Fuels

An overview on advancements in biobased transesterification methods for biodiesel production: Oil resources, extraction, biocatalysts, and process intensification technologies

Shashi Kant Bhatia et al.

Summary: Biodiesel is a non-toxic renewable energy source that is gaining global attention, with various technologies developed for industrial production, where biobased technology is considered advantageous.
Review Biochemistry & Molecular Biology

Insight into Potential Anticancer Activity of Algal Flavonoids: Current Status and Challenges

Umme Tamanna Ferdous et al.

Summary: Flavonoids, important plant chemicals, are found not only in terrestrial plants but also in microalgae and seaweeds, offering potential for novel anticancer compounds with unique chemical structures and bioactivities. Flavonoids act as antioxidants and have the ability to induce apoptosis and autophagy in cancer cells. However, research on the anticancer properties of flavonoids is mainly focused on terrestrial plants.

MOLECULES (2021)

Article Agriculture, Multidisciplinary

Biochemical and Morphological Characterization of Heterotrophic Crypthecodinium cohnii and Chlorella vulgaris Cell Walls

Greta Canelli et al.

Summary: This study investigated the composition and morphology of cell wall polysaccharides in heterotrophic Crypthecodinium cohnii and Chlorella vulgaris during growth. Glucose was found to be the major component of CWPSs and exopolysaccharides in C. cohnii, while C. vulgaris exhibited changes in cell wall thickness at different growth stages. Understanding microalgae cell wall structure can aid in developing more efficient biorefinery approaches.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Review Biotechnology & Applied Microbiology

Microbial production of omega-3 fatty acids: an overview

Nivetha Kannan et al.

Summary: Proper nutritional intake has a significant impact on maintaining basic physiological functions and body metabolism. Omega-3 fatty acids, as essential fatty acids, offer numerous benefits for human health and have received increasing attention. Transitioning from marine sources to microbial production of n-3 FAs presents a more sustainable option.

JOURNAL OF APPLIED MICROBIOLOGY (2021)

Article Biotechnology & Applied Microbiology

Evaluation of drying methods on nutritional constituents and antioxidant activities of Chlorella vulgaris cultivated in an outdoor open raceway pond

C. K. Madhubalaji et al.

Summary: The study showed that drying methods greatly impact the nutrients and bioactive compounds of Chlorella vulgaris biomass, with sun drying and lyophilization retaining the most bioactive compounds and antioxidant activities, while drum drying resulted in significant nutrient loss. Oven drying also led to a decrease in antioxidant activity and flavonoid content.

JOURNAL OF APPLIED PHYCOLOGY (2021)

Article Cardiac & Cardiovascular Systems

Chronic Infusion of Astaxanthin Into Hypothalamic Paraventricular Nucleus Modulates Cytokines and Attenuates the Renin-Angiotensin System in Spontaneously Hypertensive Rats

Hong-Li Gao et al.

Summary: The chronic administration of astaxanthin into PVN attenuated the overexpression of reactive oxygen species, NOX2, NOX4, inflammatory cytokines, and components of RAS within the PVN and suppressed hypertension. Astaxanthin played a role in the brain by improving the balance between inflammatory cytokines and components of RAS, showing a protective effect on hypertension.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2021)

Article Nutrition & Dietetics

The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes

Masaharu Urakaze et al.

Summary: This study found that oral intake of Astaxanthin for 12 weeks significantly reduced glucose levels after a 120-minute oral glucose tolerance test, improved HbA1c levels, apo E levels, and malondialdehyde-modified low-density lipoprotein levels, and increased the Matuda index.

NUTRIENTS (2021)

Review Biochemistry & Molecular Biology

Carbonyl Stress in Red Blood Cells and Hemoglobin

Olga V. Kosmachevskaya et al.

Summary: This paper discusses the susceptibility of nucleus-free mammal red blood cells (RBCs) to reactive carbonyl compounds (RCC) and the potential health issues that may arise from exposure to these compounds.

ANTIOXIDANTS (2021)

Article Biotechnology & Applied Microbiology

Can CO2 addition improve the tertiary treatment of anaerobically digested abattoir effluent (ADAE) by Scenedesmus sp. (Chlorophyta)?

Hajar Shayesteh et al.

Summary: This study assessed the potential of Scenedesmus sp. for treating anaerobically digested abattoir effluent under different pH conditions, with the highest biomass productivity observed at pH 6.5. The assimilation rate of ammoniacal nitrogen and phosphorus into algal biomass was also highest at pH 6.5, indicating the effectiveness of CO2 addition in increasing both biomass production and nutrient removal from wastewater.

ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS (2021)

Review Chemistry, Multidisciplinary

Phycoremediation of wastewater by microalgae: a review

Dimitrios Kaloudas et al.

Summary: Phycoremediation using algae for wastewater treatment is a smarter and more sustainable approach compared to classical treatments, as it removes contaminants while providing nutrients to support algal growth. This method effectively removes phosphates, nitrates, heavy metals, pesticides, hydrocarbons, nitrogen, and phosphorus from wastewater, while also inhibiting the proliferation of pathogenic bacteria. Open pond systems prove to be ideal for phycoremediation in developing countries due to their low maintenance, simple design, and reduced carbon footprint.

ENVIRONMENTAL CHEMISTRY LETTERS (2021)

Review Biochemistry & Molecular Biology

Nutraceuticals: Transformation of Conventional Foods into Health Promoters/Disease Preventers and Safety Considerations

Mudhi AlAli et al.

Summary: Nutraceuticals, essential food constituents with medicinal effects, have active compounds like carotenoids and collagen hydrolysate that positively impact cardiovascular and immune system health. Categorized based on nature and mode of action, they show potential therapeutic activities in disease prevention such as anti-cancer, antioxidant, anti-inflammatory, and anti-lipid effects. Research also covers mechanisms of action, safety for consumers, and future prospects in nutraceutical development.

MOLECULES (2021)

Article Nutrition & Dietetics

Nutritional Controlled Preparation and Administration of Different Tomato Purees Indicate Increase of β-Carotene and Lycopene Isoforms, and of Antioxidant Potential in Human Blood Bioavailability: A Pilot Study

Daniela Vitucci et al.

Summary: The study found that a higher concentration of tomato puree leads to increased bioavailability of estimated compounds and serum antioxidant potential. It sheds light on the content of nutrient precursors of vitamin A and other antioxidant compounds derived from tomatoes cooked with different strategies. Lastly, strained puree is the preferred choice according to the study findings.

NUTRIENTS (2021)

Article Agricultural Engineering

Lutein production with Chlorella sorokiniana MB-1-M12 using novel two-stage cultivation strategies-metabolic analysis and process improvement

Jih-Heng Chen et al.

Summary: Microalgae-derived carotenoids are increasingly being considered as green alternatives to synthetic antioxidants. In this study, a high-yielding lutein strain and its mutant derivative were evaluated for growth and lutein accumulation in different cultivation modes. The mutant strain showed effective growth under heterotrophic conditions but required photo-induction for lutein accumulation, with the best lutein production achieved through a two-stage cultivation strategy.

BIORESOURCE TECHNOLOGY (2021)

Review Biotechnology & Applied Microbiology

Algae biostimulants: A critical look at microalgal biostimulants for sustainable agricultural practices

Rahul Vijay Kapoore et al.

Summary: Sustaining the growing human population during climate changes requires enhanced crop quality and quantity for global food security. Transitioning to a bio-based economy through sustainable circular economy and biorefinery approaches is crucial. While macroalgae biostimulants have been well explored, commercial implementation of microalgal biostimulants is constrained by lack of research and high production costs.

BIOTECHNOLOGY ADVANCES (2021)

Article Environmental Sciences

Microalgal growth, nitrogen uptake and storage, and dissolved oxygen production in a polyculture based-open pond fed with municipal wastewater in northern Sweden

Sandra Lage et al.

Summary: Microalgal-based wastewater treatment and CO2 sequestration represent a low-cost, eco-friendly, and effective method for removing pollutants and reducing greenhouse gas emissions, supporting a circular economy. Factors affecting microalgae biomass production under outdoor cultivation impact profitability and sustainability, emphasizing the importance of considering both abiotic and biotic factors in the process.

CHEMOSPHERE (2021)

Article Environmental Sciences

Cold stress treatment enhances production of metabolites and biodiesel feedstock in Porphyridium cruentum via adjustment of cell membrane fluidity

Jim Junhui Huang et al.

Summary: The study showed that Porphyridium cruentum exhibited increased production of fatty acids and carotenoids under cold stress, leading to enhanced production of biodiesel feedstock. Principal component analysis indicated that the biosynthetic pathways of fatty acids and carotenoids in this microalga were influenced by cold stress.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

Article Food Science & Technology

The advances of characterization and evaluation methods for the compatibility and assembly structure stability of food soft matter

Qian Zhang et al.

Summary: The compatibility and assembly structure stability of food soft matter components are crucial for the development of food science and industry.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

Review Virology

Antiviral Active Compounds Derived from Natural Sources against Herpes Simplex Viruses

Lukas van de Sand et al.

Summary: Herpes simplex viruses are widely distributed with high seroprevalence in the adult population. Refractory viral infections with HSV-1 and HSV-2 present a major global health issue, especially with the increasing resistance to conventional antiviral drugs.

VIRUSES-BASEL (2021)

Review Nutrition & Dietetics

Beneficial Outcomes of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for 2021

Ivana Djuricic et al.

Summary: Oxidative stress and inflammation are important contributors to chronic non-communicable diseases. Different types of fatty acids have varying effects on chronic diseases, with moderate intake of Ω-6 fatty acids lowering the risk of cardiovascular diseases and Ω-3 fatty acids helping to reduce inflammation levels.

NUTRIENTS (2021)

Review Agronomy

Beyond the Source of Bioenergy: Microalgae in Modern Agriculture as a Biostimulant, Biofertilizer, and Anti-Abiotic Stress

Adewale Suraj Bello et al.

Summary: Microalgae extracts, rich in bioactive compounds, are widely used as biostimulants and biofertilizers in crop cultivation to promote plant growth, enhance crop resilience, and increase crop productivity.

AGRONOMY-BASEL (2021)

Article Engineering, Environmental

Phycoremediation by simulating marine aquaculture effluent using Tetraselmis sp. and the potential use of the resulting biomass

Manuel Sacristan de Alva et al.

Summary: The study demonstrates the effectiveness of Tetraselmis sp. in treating mariculture wastewater and producing biomass with accumulated lipids suitable as food for mariculture species. This approach has the potential to reduce the cost of wastewater treatment and culturing marine species.

JOURNAL OF WATER PROCESS ENGINEERING (2021)

Review Food Science & Technology

Food Ingredients and Nutraceuticals from Microalgae: Main Product Classes and Biotechnological Production

Regina Kratzer et al.

Summary: Microalgal products are emerging as a class of food, feed, and nutraceuticals, including dried biomass, isolated pigments, and extracted fat. The complex production process and high costs are major challenges, but the potential for sustainable development lies in the high-value food ingredients.
Article Nutrition & Dietetics

Dietary Polyunsaturated Fatty Acids (PUFAs): Uses and Potential Health Benefits

Bharat Kapoor et al.

Summary: PUFAs, particularly omega-3 and omega-6 fatty acids, play a crucial role in maintaining human health and protecting against diseases. These fatty acids have nutritional effects that can improve physical functioning and metabolic rate, regulating various cellular activities in the body.

CURRENT NUTRITION REPORTS (2021)

Review Energy & Fuels

Biophotonics for improving algal photobioreactor performance: A review

Emmanuel T. Sero et al.

INTERNATIONAL JOURNAL OF ENERGY RESEARCH (2020)

Article Food Science & Technology

The Colors of Health: Chemistry, Bioactivity, and Market Demand for Colorful Foods and Natural Food Sources of Colorants

Elvira Gonzalez de Mejia et al.

Annual Review of Food Science and Technology (2020)

Article Biotechnology & Applied Microbiology

Scale-up of Dunaliella salina cultivation: from strain selection to open ponds

Andrei B. Borovkov et al.

JOURNAL OF APPLIED PHYCOLOGY (2020)

Review Chemistry, Multidisciplinary

Microalgae Water Bioremediation: Trends and Hot Topics

Diana Pacheco et al.

APPLIED SCIENCES-BASEL (2020)

Article Biotechnology & Applied Microbiology

Characterization and comparison of Porphyridium sordidum and Porphyridium purpureum concerning growth characteristics and polysaccharide production

Edilberto Vicente Medina-Cabrera et al.

ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS (2020)

Review Biotechnology & Applied Microbiology

The cosmetic application of cyanobacterial secondary metabolites

Bahareh Nowruzi et al.

ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS (2020)

Review Pharmacology & Pharmacy

Microalgae as Potential Anti-Inflammatory Natural Product Against Human Inflammatory Skin Diseases

Wu-Thong Choo et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Chemistry, Physical

Harvesting Microalgae for Food and Energy Products

Julian A. Liber et al.

SMALL METHODS (2020)

Review Biochemistry & Molecular Biology

Anti-inflammatory Activity of Bioactive Compounds from Microalgae and Cyanobacteria by Focusing on the Mechanisms of Action

Maryam Tabarzad et al.

MOLECULAR BIOLOGY REPORTS (2020)

Article Environmental Sciences

Freeing land from biofuel production through microalgal cultivation in the Neotropical region

Diego F. Correa et al.

ENVIRONMENTAL RESEARCH LETTERS (2020)

Article Biotechnology & Applied Microbiology

Towards a sustainable Dunaliella salina microalgal biorefinery for 9-cis β-carotene production

Patricia J. Harvey et al.

ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS (2020)

Article Chemistry, Multidisciplinary

Propagation of Inoculum for Haematococcus pluvialis Microalgae Scale-Up Photobioreactor Cultivation System

Daniel Borowiak et al.

APPLIED SCIENCES-BASEL (2020)

Review Chemistry, Multidisciplinary

Marine Microalgae for Potential Lutein Production

Sushanta Kumar Saha et al.

APPLIED SCIENCES-BASEL (2020)

Review Biochemistry & Molecular Biology

A Mechanistic Review of β-Carotene, Lutein, and Zeaxanthin in Eye Health and Disease

Fatima Tuj Johra et al.

ANTIOXIDANTS (2020)

Review Chemistry, Multidisciplinary

Potential of microalgal compounds in trending natural cosmetics: A review

Cagla Yarkent et al.

SUSTAINABLE CHEMISTRY AND PHARMACY (2020)

Review Food Science & Technology

Reactive Oxygen Species and Antioxidants in Postharvest Vegetables and Fruits

Karlia Meitha et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCE (2020)

Article Green & Sustainable Science & Technology

Recent advances in lipid extraction using green solvents

Sergio S. de Jesus et al.

RENEWABLE & SUSTAINABLE ENERGY REVIEWS (2020)

Review Biotechnology & Applied Microbiology

Biotechnological production of astaxanthin from the microalga Haematococcus pluvialis

Xin Li et al.

BIOTECHNOLOGY ADVANCES (2020)

Article Green & Sustainable Science & Technology

Equilibrium Moisture and Drying Kinetics Modelling of Macroalgae Species Ulva ohnoi and Oedogonium intermedium

Craig Walker et al.

CLEAN TECHNOLOGIES (2020)

Article Endocrinology & Metabolism

The epidemiology of obesity

Yu Chung Chooi et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2019)

Review Biochemistry & Molecular Biology

Cyanobacteria evolution: Insight from the fossil record

Catherine F. Demoulin et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Review Biotechnology & Applied Microbiology

Light management technologies for increasing algal photobioreactor efficiency

Emeka G. Nwoba et al.

ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS (2019)

Review Green & Sustainable Science & Technology

A review of current progress of supercritical fluid technologies for e-waste treatment

Kuo Li et al.

JOURNAL OF CLEANER PRODUCTION (2019)

Review Plant Sciences

Seaweeds as nutraceuticals for health and nutrition

Emer Shannon et al.

PHYCOLOGIA (2019)

Review Food Science & Technology

Recent Advances in Microalgal Bioactives for Food, Feed, and Healthcare Products: Commercial Potential, Market Space, and Sustainability

M. U. Nethravathy et al.

COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY (2019)

Article Biochemistry & Molecular Biology

Carotenoids as Novel Therapeutic Molecules Against Neurodegenerative Disorders: Chemistry and Molecular Docking Analysis

Johant Lakey-Beitia et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Green & Sustainable Science & Technology

Insights into the microalgae cultivation technology and harvesting process for biofuel production: A review

Uganeeswary Suparmaniam et al.

RENEWABLE & SUSTAINABLE ENERGY REVIEWS (2019)

Review Chemistry, Analytical

Green techniques for extraction of bioactive carbohydrates

A. Mena-Garcia et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2019)

Review Biotechnology & Applied Microbiology

Extraction and purification of eicosapentaenoic acid and docosahexaenoic acid from microalgae: A critical review

Xiangping Li et al.

ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS (2019)

Article Food Science & Technology

Carotenoid profiling of five microalgae species from large-scale production

Gabriella Di Lena et al.

FOOD RESEARCH INTERNATIONAL (2019)

Review Endocrinology & Metabolism

The antidiabetic and antioxidant properties of some phenolic phytochemicals: A review study

Akram Ahangarpour et al.

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2019)

Review Agricultural Engineering

Recent developments of downstream processing for microbial lipids and conversion to biodiesel

Sravan Kumar Yellapu et al.

BIORESOURCE TECHNOLOGY (2018)

Article Biotechnology & Applied Microbiology

Antioxidant activity and phenolic profile in filamentous cyanobacteria: the impact of nitrogen

Dajana Blagojevic et al.

JOURNAL OF APPLIED PHYCOLOGY (2018)

Review Engineering, Chemical

Effects of water culture medium, cultivation systems and growth modes for microalgae cultivation: A review

Kit Wayne Chew et al.

JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS (2018)

Review Medicine, Research & Experimental

Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance - A review

Ramesh Kumar Saini et al.

LIFE SCIENCES (2018)

Article Materials Science, Biomaterials

Synthesis and characterization of kaempferol-based ruthenium (II) complex: A facile approach for superior anticancer application

Prakash Thangavel et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2018)

Review Oncology

Mechanisms of Phytonutrient Modulation of Cyclooxygenase-2 (COX-2) and Inflammation Related to Cancer

Shreena J. Desai et al.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2018)

Review Nutrition & Dietetics

Dietary Supplements: Regulatory Challenges and Research Resources

Johanna T. Dwyer et al.

NUTRIENTS (2018)

Article Biotechnology & Applied Microbiology

Supplemental microalgal astaxanthin produced coordinated changes in intrinsic antioxidant systems of layer hens exposed to heat stress

A. D. Magnuson et al.

ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS (2018)

Review Biotechnology & Applied Microbiology

Interkingdom microbial consortia mechanisms to guide biotechnological applications

Shu Zhang et al.

MICROBIAL BIOTECHNOLOGY (2018)

Article Biotechnology & Applied Microbiology

An overview of cosmeceutically relevant plant extracts and strategies for extraction of plant-based bioactive compounds

Nur Azzanizawaty Yahya et al.

FOOD AND BIOPRODUCTS PROCESSING (2018)

Article Veterinary Sciences

Effect of Supplementation With Omega-3 Fatty Acids, Magnesium, and Zinc on Canine Behavioral Disorders: Results of a Pilot Study

Marzieh Rahimi Niyyat et al.

TOPICS IN COMPANION ANIMAL MEDICINE (2018)

Article Agriculture, Multidisciplinary

Cellular Uptake and Intracellular Antioxidant Activity of Zein/Chitosan Nanoparticles Incorporated with Quercetin

Juan-Juan Ma et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

Continuous flow biodiesel production from wet microalgae using a hybrid thin film microfluidic platform

Eko K. Sitepu et al.

CHEMICAL COMMUNICATIONS (2018)

Article Integrative & Complementary Medicine

Chlorella sorokiniana induces mitochondrial-mediated apoptosis in human non-small cell lung cancer cells and inhibits xenograft tumor growth in vivo

Ping-Yi Lin et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2017)

Review Cell Biology

Oxidative Stress and Metabolic Syndrome: Cause or Consequence of Alzheimer's Disease?

Diana Luque-Contreras et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)

Article Biotechnology & Applied Microbiology

Separation, antitumor activities, and encapsulation of polypeptide from Chlorella pyrenoidosa

Xiaoqin Wang et al.

BIOTECHNOLOGY PROGRESS (2013)

Review Green & Sustainable Science & Technology

Development of suitable photobioreactor for algae production - A review

R. N. Singh et al.

RENEWABLE & SUSTAINABLE ENERGY REVIEWS (2012)

Article Energy & Fuels

Techno-economic analysis of autotrophic microalgae for fuel production

Ryan Davis et al.

APPLIED ENERGY (2011)

Article Plant Sciences

Anti-angiogenic effect of siphonaxanthin from green alga, Codium fragile

Ponesakki Ganesan et al.

PHYTOMEDICINE (2010)