4.6 Article

Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors

期刊

PHYSICS IN MEDICINE AND BIOLOGY
卷 68, 期 15, 页码 -

出版社

IOP Publishing Ltd
DOI: 10.1088/1361-6560/ace2a9

关键词

x-ray detector; x-ray imaging; photon counting CT; photon counting detector

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In photon counting detectors, the accumulation of electric pulses induced by multiple x-ray photons can lead to count losses. This study introduces an inexpensive readout circuit element to collect time-integrated charge to correct for pile-up-induced count losses. Experimental results demonstrate that this correction method can restore the count accuracy of paralyzable photon counting detectors, without impacting the spatial resolution of the images.
Objective. In photon counting detectors (PCDs), electric pulses induced by two or more x-ray photons can pile up and result in count losses when their temporal separation is less than the detector dead time. The correction of pulse pile-up-induced count loss is particularly difficult for paralyzable PCDs since a given value of recorded counts can correspond to two different values of true photon interactions. In contrast, charge (energy) integrating detectors work by integrating collected electric charge induced by x-rays over time and do not suffer from pile-up losses. This work introduces an inexpensive readout circuit element to the circuits of PCDs to simultaneously collect time-integrated charge to correct pile-up-induced count losses. Approach. Prototype electronics were constructed to collect time-integrated charges simultaneously with photon counts. A splitter was used to feed the electric signal in parallel to both a digital counter and a charge integrator. After recording PCD counts and integrating collected charge, a lookup table can be generated to map raw counts in the total- and high-energy bins and total charge to estimate pile-up-free true counts. Proof-of-concept imaging experiments were performed with a CdTe-based PCD array to test this method. Main results. The proposed electronics successfully recorded photon counts and time-integrated charge simultaneously, and whereas photon counts exhibited paralyzable pulse pile-up, time-integrated charge using the same electric signal as the counts measurement was linear with x-ray flux. With the proposed correction, paralyzable PCD counts became linear with input flux for both total- and high-energy bins. At high flux levels, uncorrected post-log measurements of PMMA objects severely overestimated radiological path lengths for both energy bins. After the proposed correction, the non-monotonic measurements again became linear with flux and accurately represented the true radiological path lengths. No impact on the spatial resolution was observed after the proposed correction in images of a line-pair test pattern. Significance. Time-integrated charge can be used to correct for pulse pile-up in paralyzable PCDs where analytical solutions may be difficult to use, and integrated charge can be collected simultaneously with counts using inexpensive electronics.

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