期刊
PEDIATRIC CARDIOLOGY
卷 -, 期 -, 页码 -出版社
SPRINGER
DOI: 10.1007/s00246-023-03258-y
关键词
Hypoplastic left heart syndrome; Bidirectional Glenn anastomosis; Norwood procedure; Right ventricular-pulmonary artery shunt
This study compared the surgical outcomes and hemodynamics in children with hypoplastic left heart syndrome who underwent the Norwood operation preceded by bilateral pulmonary artery banding, with either a right ventricular-pulmonary artery shunt or bidirectional Glenn anastomosis. The results showed similar pressures after the Fontan procedure in both groups, but significantly lower superior vena cava pressure after bidirectional Glenn anastomosis in the comprehensive stage II strategy group. However, the right ventricular-pulmonary artery shunt adversely influenced right ventricular volume.
As a strategy for the primary Norwood operation, the right ventricular-pulmonary artery shunt is associated with satisfactory early outcome. However, use of this shunt after bilateral pulmonary artery banding remains controversial. This study compared the operative outcomes and late hemodynamics in patients who underwent the Norwood operation, preceded by bilateral pulmonary artery banding, with a right ventricular-pulmonary artery shunt or with bidirectional Glenn anastomosis (comprehensive stage II strategy). We retrospectively reviewed 38 patients who underwent the Norwood operation preceded by bilateral pulmonary artery banding between 2004 and 2017. Of these, 17 underwent the Norwood operation with a right ventricular-pulmonary artery shunt (Group S), whereas 21 underwent the comprehensive stage II strategy (Group G). 5 years after the Norwood operation, 10 (60%) and 17 (81%) patients in Group S and Group G, respectively, underwent the Fontan procedure. Group S showed significantly lower pressure in the superior vena cava after bidirectional Glenn anastomosis than Group G (13 & PLUSMN; 2 mmHg vs. 18 & PLUSMN; 3 mmHg; p < 0.01), but pressures were similar after the Fontan procedure. The right ventricular end-diastolic volume at 1 year post-Fontan procedure was significantly higher in Group S than in Group G (142 & PLUSMN; 41% vs. 91 & PLUSMN; 28%; p < 0.01). In terms of early outcomes, the Norwood operation with a right ventricular-pulmonary artery shunt enabled low pressure in the superior vena cava, but in the long term, this shunt adversely influenced the right ventricular volume.
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