☆ 4.5 Review

Systemic lupus erythematosus: From non-coding RNAs to exosomal non-coding RNAs

PATHOLOGY RESEARCH AND PRACTICE (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Neurosciences

Non-coding RNAs and Exosomal Non-coding RNAs in Traumatic Brain Injury: the Small Player with Big Actions

Omid Mohamadzadeh et al.

Summary: Nowadays, traumatic brain injury (TBI) is a global concern due to its significant morbidity and long-term consequences that are not fully understood. Cellular pathways such as free radical production, excitotoxicity, apoptosis, and neuroinflammatory responses have been identified in TBI. Non-coding RNAs (ncRNAs) have been found to play a crucial role in post-transcriptional regulation in the brain, and altered levels of ncRNA expression have been observed in both traumatic and non-traumatic brain injuries. This review provides an overview of the primary molecular mechanisms involved in TBI and discusses the latest findings on changes and the role of ncRNAs in TBI from both clinical and experimental research.

MOLECULAR NEUROBIOLOGY (2023)

添加到收藏夹

Article Virology

Evaluation of MicroRNAs expression pattern (miR-28, miR-181a, miR-34a, and miR-31) in Patients with COVID-19 Admitted to ICU, and Diabetic COVID-19 patients

AliReza Khatami et al.

Summary: MicroRNAs (miRNAs) in peripheral blood mononuclear cells (PBMCs) may serve as diagnostic biomarkers for COVID-19 and diabetic COVID-19 patients. Selected miRNAs (miR-28, miR-31, miR-34a, and miR-181a) were measured, and their diagnostic value was determined. Bioinformatics analysis revealed their involvement in regulating inflammatory parameters and metabolic pathways. These miRNAs (miR-28, miR-34a, miR-181a) could be potential biomarkers for diagnosing COVID-19.

INTERVIROLOGY (2023)

添加到收藏夹

Review Medicine, Research & Experimental

Dysregulated expression and functions of microRNA-330 in cancers: A potential therapeutic target

Abdollah Jafarzadeh et al.

Summary: MiR-330-3p and miR-330-5p play dual roles in different cancer types, promoting or inhibiting tumor development by regulating downstream target genes and being regulated by upstream long non-coding RNAs.

BIOMEDICINE & PHARMACOTHERAPY (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

MicroRNA let-7 and viral infections: focus on mechanisms of action

Arash Letafati et al.

Summary: MicroRNAs (miRNAs) play a fundamental role in post-transcriptional regulation, with let-7 being involved in host defense and viral pathogenesis. Studies have shown that let-7-loaded extracellular vesicles (EVs) can modulate viral replication, the host antiviral response, and the action of cancer-related viruses.

CELLULAR & MOLECULAR BIOLOGY LETTERS (2022)

添加到收藏夹

Article Immunology

MicroRNA-30a Targets Notch1 to Alleviate Podocyte Injury in Lupus Nephritis

Aoyang Guo et al.

Summary: The microRNA miR-30a can ameliorate podocyte injury by suppressing the Notch1 signaling pathway, which has significant pathological implications for lupus nephritis.

IMMUNOLOGICAL INVESTIGATIONS (2022)

添加到收藏夹

Article Immunology

MicroRNA-590-3p inhibits T helper 17 cells and ameliorates inflammation in lupus mice

Junxia Huang et al.

Summary: Inhibition of T helper 17 cells through upregulation of miR-590-3p reduces inflammation in autoimmune diseases like SLE. Our study shows that miR-590-3p promotes apoptosis in Th17 cells by inhibiting autophagy, offering a promising therapeutic strategy for SLE.

IMMUNOLOGY (2022)

添加到收藏夹

Article Rheumatology

Role of micro-RNA132 and its long non coding SOX2 in diagnosis of lupus nephritis

Rasha F. Ahmed et al.

Summary: The expressions of miRNA132 and SOX2 were evaluated in SLE Egyptian patients with and without nephritis. The study found that miRNA132 and SOX2 may play a role in SLE activity and help in the early non-invasive diagnosis of LN.

LUPUS (2022)

添加到收藏夹

Article Immunology

A novel circRNA, circRACGAP1, hampers the progression of systemic lupus erythematosus via miR-22-3p-mediated AKT signalling

Han-Ying Mei et al.

Summary: In patients with SLE, down-regulated circRACGAP1 is correlated with disease severity and specific biomarkers. Overexpression of circRACGAP1 can alleviate cell apoptosis through regulating the PTEN/AKT signaling pathway by acting as a sponge of miR-22-3p. This study suggests circRACGAP1 as a potential therapeutic target for SLE treatment.

AUTOIMMUNITY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Inhibition of microRNA-448 suppresses CD4+ T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus

Jing Zhang et al.

Summary: The expression level of miR-448 is high in systemic lupus erythematosus (SLE) patients and positively correlated with disease severity. Inhibition of miR-448 can alleviate SLE symptoms, improve kidney and spleen damage, reduce inflammatory infiltration, and promote Treg cell activation.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)

添加到收藏夹

Article Medical Laboratory Technology

Novel microRNA biomarkers of systemic lupus erythematosus in plasma: miR-124-3p and miR-377-3p

Ling Yan et al.

Summary: The expression of miR-124-3p and miR-377-3p is significantly upregulated in SLE patients and may serve as potential biomarkers for SLE diagnosis. The combined diagnostic efficiency of plasma miR-124-3p and miR-377-3p is higher than using them alone, and their AUC values in plasma are higher than in PBMCs. Plasma miR-124-3p expression is associated with clinical parameters such as antiC1q and C3, and miR-377-3p is an independent predictor for SLE. Plasma miR-124-3p is also independently associated with the remission rate of SLE.

CLINICAL BIOCHEMISTRY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

MiR-145 participates in the development of lupus nephritis by targeting CSF1 to regulate the JAK/STAT signaling pathway

Wang Liao et al.

Summary: The study revealed that miR-145 regulates the progression of LN through the CSF1-mediated JAK/STAT signaling pathway, suggesting that miR-145 may serve as a new therapeutic target for LN treatment.

CYTOKINE (2022)

添加到收藏夹

Article Medicine, Research & Experimental

CircRTN4 aggravates mesangial cell dysfunction by activating the miR-513a-5p/FN axis in lupus nephritis

Xinyan Miao et al.

Summary: In lupus nephritis, circRNA circRTN4 exacerbates mesangial cell dysfunction through activation of the miR-513a-5p/FN axis. Its expression is significantly enhanced in lupus nephritis patients, indicating its potential as a biomarker and therapeutic target for lupus nephritis.

LABORATORY INVESTIGATION (2022)

添加到收藏夹

Review Genetics & Heredity

Effects of microRNAs and long non-coding RNAs on chemotherapy response in glioma

Sara Ahmadpour et al.

Summary: Glioma is a common invasive primary tumor of the central nervous system, and treatment resistance remains a problem. Non-coding RNAs play a role in the mechanisms of treatment resistance. This review discusses the pathways by which microRNAs and long non-coding RNAs affect resistance to chemotherapy and radiotherapy, and offers potential therapeutic options for future glioma treatment.

EPIGENOMICS (2022)

添加到收藏夹

Review Medicine, Research & Experimental

Microfluidics for detection of exosomes and microRNAs in cancer: State of the art

Seyed Mojtaba Mousavi et al.

Summary: Exosomes, small extracellular vesicles that can be taken up by target cells for cell-to-cell communication, have shown significant advancements in diagnosis, prognosis, and treatment in various conditions, such as cancer. However, the conventional isolation and evaluation methods of exosomes face challenges, leading to the potential use of microfluidics technology for improved detection and monitoring of cancer-related exosomes.

MOLECULAR THERAPY-NUCLEIC ACIDS (2022)

添加到收藏夹

Review Oncology

Non-coding RNAs and glioblastoma: Insight into their roles in metastasis

Seyed Mojtaba Mousavi et al.

Summary: This review discusses the ncRNAs associated with metastasis in GBM, including miRNAs, circRNAs, and lncRNAs. Dysregulation of these ncRNAs may facilitate invasion and metastasis of glioma.

MOLECULAR THERAPY-ONCOLYTICS (2022)

添加到收藏夹

Review Medicine, Research & Experimental

Interplays between non-coding RNAs and chemokines in digestive system cancers

Abdollah Jafarzadeh et al.

Summary: The altered expression of chemokines/chemokine receptors plays an important role in malignancies, affecting processes such as cell infiltration, metastasis, and proliferation. Non-coding RNAs also contribute to the development of digestive system malignancies by regulating the expression of chemokines/chemokine receptors.

BIOMEDICINE & PHARMACOTHERAPY (2022)

添加到收藏夹

Article Medical Laboratory Technology

Association between genetic variants of microRNA-21 and microRNA-155 and systemic lupus erythematosus: A case-control study from a Chinese population

Rong Wang et al.

Summary: This study found that genetic variants of rs767649 and rs13137 are associated with susceptibility to SLE, and the expression levels of miR-21 and miR-155 are significantly increased in SLE patients.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2022)

添加到收藏夹

Review Oncology

Non-coding RNAs and glioma: Focus on cancer stem cells

Ali Rajabi et al.

Summary: This article provides a review of the role of ncRNAs in glioma development, particularly their effects on CSCs. ncRNAs play a crucial role in tumor development and progression through various mechanisms, including chromatin remodeling and modification, transcriptional regulation, mRNA stability, and protein translation.

MOLECULAR THERAPY-ONCOLYTICS (2022)

添加到收藏夹

Review Oncology

Exosomal long non-coding RNAs: novel molecules in gastrointestinal cancers' progression and diagnosis

Mohammad Roshani et al.

Summary: Exosomal lncRNAs play a crucial role in the biology of gastrointestinal cancer and can be utilized as biomarkers for diagnosis, prognosis, and potential treatment targets.

FRONTIERS IN ONCOLOGY (2022)

添加到收藏夹

Article Neurosciences

MicroRNAs and Synaptic Plasticity: From Their Molecular Roles to Response to Therapy

Amir Hossein Mohammadi et al.

Summary: Synaptic plasticity refers to the ability of synapses to weaken or strengthen over time, with miRNAs playing crucial roles in regulating this process. Dysregulation of miRNAs may be associated with pathological alterations in synaptic plasticity, leading to diseases. Understanding the impact of miRNAs on synaptic plasticity provides insights for the diagnosis and treatment of related diseases and drug addiction.

MOLECULAR NEUROBIOLOGY (2022)

添加到收藏夹

Review Cell Biology

Role of non-coding RNAs and exosomal non-coding RNAs in retinoblastoma progression

Nasrin Ahangar Davoodi et al.

Summary: Retinoblastoma (RB) is a rare aggressive intraocular malignancy of childhood that can have severe consequences. Non-coding RNAs (ncRNAs) play important roles in the pathogenesis and development of RB, with different ncRNAs acting as either tumor promoters or suppressors. Understanding the regulatory mechanisms of ncRNAs provides new opportunities for RB therapy.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Epigenetic regulation in myocardial infarction: Non-coding RNAs and exosomal non-coding RNAs

Sara Fadaei et al.

Summary: Myocardial infarction (MI) is a leading cause of global deaths. Non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), have been found to regulate pathological processes in MI, and exosomal ncRNAs have been shown to play important roles in cell communication and disease development. Therefore, understanding the role of ncRNAs and exosomal ncRNAs in MI is of great significance for diagnosis and prognosis.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

添加到收藏夹

Review Oncology

Lysophosphatidic Acid Signaling and microRNAs: New Roles in Various Cancers

Mahdi Rafiyan et al.

Summary: MiRNAs play critical roles in regulating gene expression in both normal and cancer cells. Lysophosphatidic acid (LPA) signaling can induce overexpression of miRNAs, whose functional roles remain to be fully clarified. RNA-based treatments hold great promise in personalized medicine.

FRONTIERS IN ONCOLOGY (2022)

添加到收藏夹

Review Medicine, Research & Experimental

Cytokines and microRNAs in SARS-CoV-2: What do we know?

Fahimeh Zamani Rarani et al.

Summary: The COVID-19 pandemic is a global health emergency and there is currently no completely effective treatment. This review discusses the cytokines involved in the cytokine storm seen in severe COVID-19 patients and whether they can be used for treatment.

MOLECULAR THERAPY-NUCLEIC ACIDS (2022)

添加到收藏夹

Review Cell Biology

MicroRNA-383: A tumor suppressor miRNA in human cancer

Abdollah Jafarzadeh et al.

Summary: miR-383 is an anti-tumor miRNA that is downregulated in many types of cancer. It attenuates several cancer-related processes and promotes apoptosis by directly targeting the mRNA of pro-tumor genes. Restoring the expression of miR-383 could be a potential treatment approach for cancer.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Role of Resveratrol in Modulating microRNAs in Human Diseases: From Cancer to Inflammatory Disorder

Atefeh Amiri et al.

Summary: Cancer and inflammatory disorders are significant public health issues globally, and new therapeutic strategies are needed. Natural compounds like resveratrol have shown potential for treating these diseases by targeting cellular and molecular mechanisms, including microRNAs.

CURRENT MEDICINAL CHEMISTRY (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Exosomes and Lung Cancer: Roles in Pathophysiology, Diagnosis and Therapeutic Applications

Atefeh Amiri et al.

Summary: Exosomes, as novel biomarkers, have the potential to play a key role in the diagnosis of lung cancer.

CURRENT MEDICINAL CHEMISTRY (2021)

添加到收藏夹

Article Urology & Nephrology

Urinary exosomal miR-146a as a marker of albuminuria, activity changes and disease flares in lupus nephritis

Javier Perez-Hernandez et al.

Summary: Urinary exosomal miR-146a levels are correlated with lupus activity, proteinuria and histological features, discriminating patients with lupus nephritis and serving as a good baseline marker for SLE flares. The study also identified a significant biological association between miR-146a and the TRAF6 axis in the progression of lupus nephritis renal fibrosis.

JOURNAL OF NEPHROLOGY (2021)

添加到收藏夹

Review Cell Biology

Effects of therapeutic probiotics on modulation of microRNAs

Amirhossein Davoodvandi et al.

Summary: Probiotics are beneficial bacteria that can compete with pathogenic microorganisms and regulate the host immune response, resulting in preventive and therapeutic effects. Dysbiosis may contribute to various pathological conditions, while miRNAs play a crucial role in almost all cellular signaling pathways in both healthy and diseased states.

CELL COMMUNICATION AND SIGNALING (2021)

添加到收藏夹

Article Cell Biology

HDAC1 potentiates CD4+T cell activation by inhibiting miR-124 and promoting IRF1 in systemic lupus erythematosus

Jie Chen et al.

Summary: The study revealed that the under-expression of miR-124 in CD4 + T cells from SLE patients inhibits immunoactivity by down-regulating IRF1. HDAC1 enrichment at the miR-124 promoter suppresses miR-124 expression, thereby promoting CD4 + T cell immunoactivity. This finding suggests that HDAC1 may play a role in the immunopathology of SLE.

CELLULAR IMMUNOLOGY (2021)

添加到收藏夹

Review Oncology

Gynecologic cancers and non-coding RNAs: Epigenetic regulators with emerging roles

Zahra Sadat Razavi et al.

Summary: Gynecologic cancers involve female genital organs and are influenced by personal lifestyle, exposure history, genetics, and other factors. Research has shown that non-coding RNAs play a significant role in the regulation of cellular function in gynecological cancer, potentially leading to new avenues for diagnosis and treatment.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2021)

添加到收藏夹

Article Rheumatology

Genome-wide association study on Northern Chinese identifies KLF2, DOT1L and STAB2 associated with systemic lupus erythematosus

Qin Song et al.

Summary: This study identified three loci associated with SLE, with KLF2 likely being a Chinese-specific locus. DOT1L and KLF2 are considered plausible targets for SLE treatment.

RHEUMATOLOGY (2021)

添加到收藏夹

Article Genetics & Heredity

Altered expression of miR-142, miR-155, miR-499a and of their putative common target MDM2 in systemic lupus erythematosus

Andrea Latin et al.

Summary: The study evaluated the genetic and expression variability of three miRNAs potentially involved in systemic lupus erythematosus (SLE), and identified down-expression of miR-142 and miR-499a in patients, with a trend for down-expression of miR-155. The lower expression of miR-142 was associated with a specific polymorphism variant allele, and predictive analyses identified MDM2 as a target gene common to the three miRNAs. These findings suggest that the three miRNAs and MDM2 may play a role in SLE.

EPIGENOMICS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression

Guojun Hou et al.

Summary: This study identified a risk variant for systemic lupus erythematosus, which disrupts a regulatory element and modulates miR-146a expression. The variant tags a cell-type specific distal enhancer that interacts with the miR-146a promoter, affecting NF-kB binding and miR-146a expression. Furthermore, CRISPR activation-based modulation of this enhancer attenuates type I interferon pathway activation in SLE patients by increasing miR-146a expression.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Cell Biology

Targeting of EIF4EBP1 by miR-99a-3p affects the functions of B lymphocytes via autophagy and aggravates SLE disease progression

Meng Yang et al.

Summary: Excessive activation of immune cells in the pathogenesis of systemic lupus erythematosus (SLE) is regulated by miRNAs, with miR-99a-3p found to be downregulated in SLE patients. Through targeting EIF4EBP1, miR-99a-3p affects the proliferation and apoptosis of B cells, suggesting potential therapeutic targets in SLE treatment.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

添加到收藏夹

Review Oncology

Exosomal microRNAs and exosomal long non-coding RNAs in gynecologic cancers

Maryam Hashemipour et al.

Summary: miRNAs and lncRNAs play essential biological roles through various mechanisms, regulating gene expression and driving pathways in gynecological cancers. Exosomes serve as natural carriers of non-coding RNAs, focusing research on exosomal microRNAs and long non-coding RNAs for potential therapeutic applications.

GYNECOLOGIC ONCOLOGY (2021)

添加到收藏夹

Article Cell Biology

Pioglitazone Attenuates Lupus Nephritis Symptoms in Mice by Modulating miR-21-5p/TIMP3 Axis: the Key Role of the Activation of Peroxisome Proliferator-Activated Receptor-γ

Ding Liu et al.

Summary: The study found that improving lupus nephritis renal structure and function and inhibiting autoimmune response can be achieved by inhibiting miR-21-5p. Pioglitazone can protect against lupus nephritis by inhibiting miR-21-5p through activating PPAR gamma.

INFLAMMATION (2021)

添加到收藏夹

Article Cell Biology

Regulation of Toll-like receptor-mediated inflammatory response by microRNA-152-3p-mediated demethylation of MyD88 in systemic lupus erythematosus

Bei Tao et al.

Summary: miR-152-3p is highly expressed in CD4(+) T cells and PBMCs of SLE patients, and is associated with clinical symptoms, it regulates MyD88 methylation by inhibiting DNMT1, thus promoting TLR-mediated inflammatory response in SLE.

INFLAMMATION RESEARCH (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Circulating miR-181a and miR-223 expression with the potential value of biomarkers for the diagnosis of systemic lupus erythematosus and predicting lupus nephritis

Rehab S. Abdul-Maksoud et al.

Summary: miR-181a was found to be up-regulated in SLE patients, with higher expression in the LN group compared to the non-LN group, while miR-223 was down-regulated in SLE patients, with lower expression in the LN group compared to the non-LN group. The expression levels of miR-181a and miR-223 were associated with the severity of LN and could serve as indicators for evaluating SLE progression and prognosis.

JOURNAL OF GENE MEDICINE (2021)

添加到收藏夹

Article Oncology

miR-101-3p negatively regulates inflammation in systemic lupus erythematosus via MAPK1 targeting and inhibition of the NF-κB pathway

Xiaoying Zhao et al.

Summary: miR-101-3p is downregulated in SLE PBMCs and negatively regulates IL-10 and IFN-γ expression by targeting MAPK1. Overexpression of miR-101-3p attenuates the inflammatory response in SLE PBMCs by inhibiting MAPK1 expression and blocking the NF-κB pathway. These findings reveal a novel regulatory mechanism in SLE inflammation and suggest a new direction for the development of SLE treatments.

MOLECULAR MEDICINE REPORTS (2021)

添加到收藏夹

Article Medicine, Research & Experimental

MicroRNA-98-5p inhibits human mesangial cell proliferation and TNF-α and IL-6 secretion by targeting BTB and CNC homology 1

Yong Du et al.

Summary: The study revealed that miR-98-5p inhibited human mesangial cell proliferation and the secretion of TNF-alpha and IL-6 by targeting BACH1, suggesting that miR-98-5p and BACH1 could be potential therapeutic targets for LN.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2021)

添加到收藏夹

Review Genetics & Heredity

miRNA-148b and its role in various cancers

Najmeh Dorraki et al.

Summary: miR-148b is a tumor suppressor that can regulate various oncogenes, with prognostic and diagnostic potential. It may undergo deregulation in different cancers, making it a potential therapeutic target or biomarker that requires further investigation.

EPIGENOMICS (2021)

添加到收藏夹

Article Immunology

Downregulated Serum Exosomal miR-451a Expression Correlates With Renal Damage and Its Intercellular Communication Role in Systemic Lupus Erythematosus

Lina Tan et al.

Summary: This study showed that downregulated serum exosomal miR-451a expression is correlated with SLE disease activity and renal damage, and revealed its intercellular communication role in SLE, providing potential therapeutic strategies.

FRONTIERS IN IMMUNOLOGY (2021)

添加到收藏夹

Article Health Care Sciences & Services

Macrophage colony-stimulating factor could evaluate both disease activity and renal involvement in systemic lupus erythematosus

Rong Wang et al.

Summary: Aberrations of monocyte/macrophage-associated cytokines play a crucial role in systemic lupus erythematosus (SLE). Among the studied cytokines, IL-6, IFN-gamma, and TNF-alpha were significant predictors of SLE activity, while M-CSF emerged as a promising marker for both disease activity and renal involvement in SLE patients. The higher expression of M-CSF mRNA in monocytes from SLE patients suggests a potential role of monocytes in the elevated levels of M-CSF.

ANNALS OF PALLIATIVE MEDICINE (2021)

添加到收藏夹

Article Health Care Sciences & Services

MiR-301a-3p Advances IRAK1-Mediated Differentiation of Th17 Cells to Promote the Progression of Systemic Lupus Erythematosus via Targeting PELI1

Shuaihantian Luo et al.

Summary: In this study, the researchers found that miR-301a-3p was significantly upregulated in PBMCs of SLE patients, and it may be involved in the progression of SLE by promoting the expression of inflammatory factors and the differentiation of Th17 cells. PELI1 was identified as a target of miR-301a-3p, and its upregulation could reverse the effects of miR-301a-3p on PBMCs. Furthermore, miR-301a-3p was also found to promote the expression of IRAK1 and contribute to the progression of SLE by targeting PELI1.

JOURNAL OF HEALTHCARE ENGINEERING (2021)

添加到收藏夹

Review Medicine, Research & Experimental

The role of non-coding RNAs in chemotherapy for gastrointestinal cancers

Fatemeh Dashti et al.

Summary: Chemoresistance is a major challenge in treating advanced GI cancers, with non-coding RNAs playing a critical role in inducing resistance by affecting multiple signaling pathways and gene expression regulation.

MOLECULAR THERAPY-NUCLEIC ACIDS (2021)

添加到收藏夹

Review Oncology

Non-coding RNAs related to angiogenesis in gynecological cancer

Neda Rahimian et al.

Summary: Gynecological cancer is influenced by non-coding RNAs, particularly microRNAs, which regulate angiogenesis. Understanding the molecular mechanisms of microRNAs in regulating angiogenesis may offer new treatment options for gynecological cancer.

GYNECOLOGIC ONCOLOGY (2021)

添加到收藏夹

Article Cell Biology

Association of LncRNA-GAS5 gene polymorphisms and PBMC LncRNA-GAS5 level with risk of systemic lupus erythematosus in Chinese population

Chun-Hong Liu et al.

Summary: This study focused on the association of LncRNA-GAS5 polymorphism with SLE risk and explored its involvement in the disease's occurrence. The rs145204276 ID/DD genotypes were found to be associated with a decreased risk of SLE and a reduced incidence of renal disorders. Additionally, the LncRNA-GAS5/miR-21/PTEN signaling pathway was identified to play a role in SLE development, where LncRNA-GAS5 acted as an miR-21 target regulating PTEN expression.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

添加到收藏夹

Review Cell Biology

Roles of Non-coding RNAs and Angiogenesis in Glioblastoma

Ebrahim Balandeh et al.

Summary: Non-coding RNAs play a crucial role in regulating angiogenesis in glioblastoma, affecting gene transcription and the expression of angiogenesis-inducing molecules through various mechanisms.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

添加到收藏夹

Article Medicine, General & Internal

Diagnostic significance of circulating miR-485-5p in patients with lupus nephritis and its predictive value evaluation for the clinical outcomes

Qinghua Wu et al.

Summary: MiR-485-5p is highly expressed in SLE and LN patients, serving as a potential biomarker for early diagnosis of LN and predicting the risk of ESRD in LN patients.

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION (2021)

添加到收藏夹

Article Rheumatology

Association of microRNA-125a with the clinical features, disease activity and inflammatory cytokines of juvenile-onset lupus patients

Eman Eissa et al.

Summary: The study found that the expression levels of miR-125a were significantly reduced in jSLE patients and associated with disease activity and clinical manifestations. The plasma levels of IL-17 and IFN-gamma in jSLE patients were significantly higher. The findings suggest that miR-125a could be a potential therapeutic target for inflammation regulation in jSLE patients.

LUPUS (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Lupus Vasculitis: An Overview

Patrizia Leone et al.

Summary: Lupus vasculitis is a common complication occurring in approximately 50% of patients with systemic lupus erythematosus, involving different organ systems and presenting with various clinical manifestations. A poor prognosis is often associated with lupus vasculitis, requiring prompt diagnosis for a better outcome. Treatment strategies depend on the organs involved and the severity of the vasculitis.

BIOMEDICINES (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

HIF-1α and miR-210 differential and lineage-specific expression in systemic lupus erythematosus

Barry Garchow et al.

Summary: Differential expression of HIF-1 alpha and miR-210 in systemic lupus erythematosus patients contributes to SLE immune pathology and may represent a novel and important regulatory axis in SLE.

MOLECULAR IMMUNOLOGY (2021)

添加到收藏夹

Article Rheumatology

Estrogen-Induced hsa-miR-10b-5p Is Elevated in T Cells From Patients With Systemic Lupus Erythematosus and Down-Regulates Serine/Arginine-Rich Splicing Factor 1

Suruchi A. Ramanujan et al.

Summary: This study revealed a previously unknown molecular link between estrogen and gene regulation in immune cells through miRNA-mediated regulation of SRSF1 in T cells. Elevated levels of miRNA were found in T cells from healthy women and SLE patients, suggesting potential implications for systemic autoimmune diseases.

ARTHRITIS & RHEUMATOLOGY (2021)

添加到收藏夹

Article Medicine, Research & Experimental

New epigenetic players in stroke pathogenesis: From non-coding RNAs to exosomal non-coding RNAs

Maryam Mahjoubin-Tehran et al.

Summary: Non-coding RNAs, especially microRNAs and lncRNAs, play critical roles in angiogenesis and neuroprotection following ischemic stroke. Exosomes, serving as nanocarriers, are capable of transferring various ncRNAs and have significant inter-cellular roles in the mediation of neuro-restorative events after stroke. This review summarizes the pathogenic role of ncRNAs and exosomal ncRNAs in stroke.

BIOMEDICINE & PHARMACOTHERAPY (2021)

添加到收藏夹

Article Urology & Nephrology

miR-1968-5p is involved in the pathogenesis of lupus nephritis of NZBWF1 mice by targeting csf1

Shipeng Li et al.

Summary: The study used microarray technology to investigate the mRNA and miRNA expression profiles of NZBWF1 mice with lupus nephritis. Results showed significant changes in miR-1968-5p and csf1 mRNA expression in lupus nephritis mice. Experimental and bioinformatics analysis confirmed that miR-1968-5p may be involved in the pathogenesis of lupus nephritis through targeting csf1.

CLINICAL AND EXPERIMENTAL NEPHROLOGY (2021)

添加到收藏夹

Article Cell Biology

CircELK4 Contributes to Lupus Nephritis by Acting as a miR-27b-3p Sponge to Regulate STING/IRF3/IFN-I Signaling

Zhi-Quan Xu et al.

Summary: By investigating the function of the circELK4/miR-27b-3p axis in LN, it was revealed that circELK4 promotes inflammation and cell apoptosis by modulating STING/IRF3/IFN-I signaling, contributing to renal injury in LN patients.

INFLAMMATION (2021)

添加到收藏夹

Article Immunology

Acute and post-acute phase of COVID-19: Analyzing expression patterns of miRNA-29a-3p, 146a-3p, 155-5p, and let-7b-3p in PBMC

Tahereh Donyavi et al.

Summary: This study aimed to identify specific miRNA profiles that can be used as biomarkers to differentiate acute COVID-19 cases, healthy individuals, and those in the post-acute phase. The results showed that miR-29a-3p, miR-146a-3p, and let-7b-3p were significantly elevated in COVID-19 patients compared to healthy individuals, with potential for high sensitivity and specificity in COVID-19 diagnosis and monitoring. MiR-29a-3p and miR-146a-3p also showed promise as biomarkers for distinguishing acute from post-acute phases of COVID-19.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

添加到收藏夹

Article Rheumatology

The high expression of miR-564 in patients with systemic lupus erythematosus promotes differentiation and maturation of DC cells by negatively regulating TP53 expression in vitro

Ziyue Teng et al.

Summary: The highly expressed miR-564 promotes the maturation and proliferation of Mo-DC cells by negatively regulating TP53 expression. Transfection with miR-564 antagomir significantly inhibits the differentiation, maturation, and proliferation of Mo-DC cells. Co-transfection of miR-564 antagomir and TP53 si-RNA restores the proliferation and migration of DC cells in rescue experiments.

LUPUS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circular RNA-0007059 protects cell viability and reduces inflammation in a nephritis cell model by inhibiting microRNA-1278/SHP-1/STAT3 signaling

Peng-Wei Guo et al.

Summary: The study shows that circ_0007059 protects RMCs against apoptosis and inflammation during nephritis by attenuating miR-1278/SHP-1/STAT3 signaling.

MOLECULAR MEDICINE (2021)

添加到收藏夹

Review Medicine, Research & Experimental

Cell death pathways and viruses: Role of microRNAs

Javid Sadri Nahand et al.

Summary: Viral infections can alter cell death pathways and affect the life and death of cells.

MOLECULAR THERAPY-NUCLEIC ACIDS (2021)

添加到收藏夹

Review Oncology

Angiogenesis-related non-coding RNAs and gastrointestinal cancer

Zahra Sadat Razavi et al.

Summary: Angiogenesis plays a crucial role in the growth and metastasis of GI cancers, with ncRNAs being key regulators of this process. Despite incomplete understanding of the mechanisms involved, research indicates that ncRNAs could be potential targets for future therapeutic interventions.

MOLECULAR THERAPY-ONCOLYTICS (2021)

添加到收藏夹

Article Immunology

Hsa_circ_0010957 knockdown attenuates lipopolysaccharide-induced HK2 cell injury by regulating the miR-1224-5p/IRAK1 axis

Jiaojiao Pan et al.

Summary: In this study, the function and mechanism of circRNA hsa_circ_0010957 in lupus nephritis were investigated using a LPS-induced cellular model. The results showed that hsa_circ_0010957 regulates LPS-induced cell damage through the miR-1224-5p/IRAK1 axis.

CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY (2021)

添加到收藏夹

Article Rheumatology

Hsa_circ_0123190 acts as a competitive endogenous RNA to regulate APLNR expression by sponging hsa-miR-483-3p in lupus nephritis

Chunyi Zhang et al.

Summary: This study identified 159 dysregulated circRNAs in LN patients, including hsa_circ_0123190 with significantly decreased expression. Hsa_circ_0123190 was found to regulate APLNR expression by sponging hsa-miR-483-3p, which in turn influenced the fibrotic-related protein TGF-beta 1, suggesting a potential mechanism of circRNA involvement in LN pathogenesis.

ARTHRITIS RESEARCH & THERAPY (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Human umbilical cord-derived mesenchymal stem cell therapy ameliorates lupus through increasing CD4+T cell senescence via MiR-199a-5p/Sirt1/p53 axis

Tao Cheng et al.

Summary: The study demonstrated that hUC-MSCs transplantation alleviated lupus symptoms and increased splenic CD4+ T cell senescence through the Sirt1/p53 pathway via miR-199a-5p in the MRL/lpr lupus mouse model, indicating a potential therapeutic mechanism for lupus disease.

THERANOSTICS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Diacerein Downregulates NLRP3/Caspase-1/IL-1β and IL-6/STAT3 Pathways of Inflammation and Apoptosis in a Rat Model of Cadmium Testicular Toxicity

Amr A. Fouad et al.

BIOLOGICAL TRACE ELEMENT RESEARCH (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Role of microRNAs in Chronic Lymphocytic Leukemia Pathogenesis

Ehsan Javandoost et al.

CURRENT MEDICINAL CHEMISTRY (2020)

添加到收藏夹

Review Medicine, Research & Experimental

The Role of MicroRNAs in Lung Cancer: Implications for Diagnosis and Therapy

Parisa Naeli et al.

CURRENT MOLECULAR MEDICINE (2020)

添加到收藏夹

Article Cell Biology

DRD3 (dopamine receptor D3) but not DRD2 activates autophagy through MTORC1 inhibition preserving protein synthesis

Pedro Barroso-Chinea et al.

AUTOPHAGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Chaperone-mediated autophagy regulates apoptosis and the proliferation of colon carcinoma cells

Jie-qiong Peng et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

添加到收藏夹

Article Infectious Diseases

MicroRNAs and exosomes: key players in HIV pathogenesis

J. Sadri Nahand et al.

HIV MEDICINE (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Exosomes and cancer: From oncogenic roles to therapeutic applications

Soheila Mohammadi et al.

IUBMB LIFE (2020)

添加到收藏夹

Review Oncology

Circular RNAs and gastrointestinal cancers: Epigenetic regulators with a prognostic and therapeutic role

Parisa Naeli et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2020)

添加到收藏夹

Review Medicine, Research & Experimental

Circular RNA and Diabetes: Epigenetic Regulator with Diagnostic Role

Kazem Abbaszadeh-Goudarzi et al.

CURRENT MOLECULAR MEDICINE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity

Lingyan Chen et al.

HUMAN MOLECULAR GENETICS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

The Urinary Exosomal miRNA Expression Profile is Predictive of Clinical Response in Lupus Nephritis

Eloi Garcia-Vives et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

The role of miR-146a in viral infection

Javid Sadri Nahand et al.

IUBMB LIFE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Downregulation of microRNA-101-3p participates in systemic lupus erythematosus progression via negatively regulating HDAC9

Huanxia Sun et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2020)

添加到收藏夹

Review Genetics & Heredity

Exosomal miRNAs: novel players in viral infection

Javid Sadri Nahand et al.

EPIGENOMICS (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Apoptotic functions of microRNAs in pathogenesis, diagnosis, and treatment of endometriosis

Mona Taghavipour et al.

CELL AND BIOSCIENCE (2020)

添加到收藏夹

Article Immunology

MiR-153-3p induces immune dysregulation by inhibiting PELI1 expression in umbilical cord-derived mesenchymal stem cells in patients with systemic lupus erythematosus

Dan Li et al.

AUTOIMMUNITY (2020)

添加到收藏夹

Article Medicine, Research & Experimental

Circular RNAs: new genetic tools in melanoma

Jamal Hallajzadeh et al.

BIOMARKERS IN MEDICINE (2020)

添加到收藏夹

Article Rheumatology

Association of the Polymorphism rs13259960 in SLEAR With Predisposition to Systemic Lupus Erythematosus

Zhen Fan et al.

ARTHRITIS & RHEUMATOLOGY (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Autophagy regulation by microRNAs: Novel insights into osteosarcoma therapy

Zeinab Jamali et al.

IUBMB LIFE (2020)

添加到收藏夹

Article Immunology

Antagonizing miR-7 suppresses B cell hyperresponsiveness and inhibits lupus development

Min Wang et al.

JOURNAL OF AUTOIMMUNITY (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Interaction of miR-181b and IFNA1 Polymorphisms on the Risk of Systemic Lupus Erythematosus

Yong-Ling He et al.

BIOMED RESEARCH INTERNATIONAL (2020)

添加到收藏夹

Article Rheumatology

MicroRNAs in Systemic Lupus Erythematosus: a Perspective on the Path from Biological Discoveries to Clinical Practice

Soon-Min Hong et al.

CURRENT RHEUMATOLOGY REPORTS (2020)

添加到收藏夹

Article Rheumatology

Hsa_circ_0012919 regulates expression of MDA5 by miR-125a-3p in CD4+T cells of systemic lupus erythematous

Chengzhong Zhang et al.

LUPUS (2020)

添加到收藏夹

Review Medicine, Research & Experimental

Non-coding RNAs and Exosomes: Their Role in the Pathogenesis of Sepsis

Seyed MohammadReza Hashemian et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

添加到收藏夹

Article Oncology

Downregulated miR-29a promotes B cell overactivation by upregulating Crk-like protein in systemic lupus erythematosus

Xinyu Shi et al.

MOLECULAR MEDICINE REPORTS (2020)

添加到收藏夹

Article Pathology

miR-133 inhibits proliferation and promotes apoptosis by targeting LASP1 in lupus nephritis

Zhimin Huang et al.

EXPERIMENTAL AND MOLECULAR PATHOLOGY (2020)

添加到收藏夹

Article Cell Biology

LncRNA NEAT1 accelerates renal mesangial cell injury via modulating the miR-146b/TRAF6/NF-κB axis in lupus nephritis

Li-Hua Zhang et al.

CELL AND TISSUE RESEARCH (2020)

添加到收藏夹

Review Cell Biology

Autophagy in cancers including brain tumors: role of MicroRNAs

Mohammad Hossein Pourhanifeh et al.

CELL COMMUNICATION AND SIGNALING (2020)

添加到收藏夹

Article Immunology

LncRNA GAS5 suppresses CD4+ T cell activation by upregulating E4BP4 via inhibiting miR-92a-3p in systemic lupus erythematosus

Qian Liu et al.

IMMUNOLOGY LETTERS (2020)

添加到收藏夹

Review Microbiology

Circular RNAs: New Epigenetic Signatures in Viral Infections

Javid Sadri Nahand et al.

FRONTIERS IN MICROBIOLOGY (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Nanomaterials for Autophagy-Related miRNA-34a Delivery in Cancer Treatment

Priyanka Sharma et al.

FRONTIERS IN PHARMACOLOGY (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Role of microRNAs in Staphylococcus aureus infection: Potential biomarkers and mechanism

Rasoul Mirzaei et al.

IUBMB LIFE (2020)

添加到收藏夹

Review Medicine, Research & Experimental

Circular RNA as a potential diagnostic and/or therapeutic target for endometriosis

Parisa M. Dana et al.

BIOMARKERS IN MEDICINE (2020)

添加到收藏夹

Review Cell Biology

Role of exosomes in malignant glioma: microRNAs and proteins in pathogenesis and diagnosis

Amir B. Ghaemmaghami et al.

CELL COMMUNICATION AND SIGNALING (2020)

添加到收藏夹

Review Cell Biology

Exosomal microRNAs derived from mesenchymal stem cells: cell-to-cell messages

Kasra Asgarpour et al.

CELL COMMUNICATION AND SIGNALING (2020)

添加到收藏夹

Review Cell Biology

The effect of miRNA and autophagy on colorectal cancer

Jiali Long et al.

CELL PROLIFERATION (2020)

添加到收藏夹

Article Medicine, Research & Experimental

Myeloid-derived suppressor cells shift Th17/Treg ratio and promote systemic lupus erythematosus progression through arginase-1/miR-322-5p/TGF-β pathway

Bo Pang et al.

CLINICAL SCIENCE (2020)

添加到收藏夹

Review Oncology

Autophagy-related MicroRNAs in chronic lung diseases and lung cancer

Samaneh Rezaei et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2020)

添加到收藏夹

Article Oncology

MicroRNA-183 exerts a protective role in lupus nephritis through blunting the activation of TGF-β/Smad/TLR3 pathway via reducing Tgfbr1

Huimeng Qi et al.

EXPERIMENTAL CELL RESEARCH (2020)

添加到收藏夹

Article Immunology

The assessment of selected MiRNAs profile in HIV, HBV, HCV, HIV/HCV, HIV/HBV Co-infection and elite controllers for determination of biomarker

Sepehr Yousefpouran et al.

MICROBIAL PATHOGENESIS (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Sensing the scent of death: Modulation of microRNAs by Curcumin in gastrointestinal cancers

Milad Ashrafizadeh et al.

PHARMACOLOGICAL RESEARCH (2020)

添加到收藏夹

Review Genetics & Heredity

Exosomal microRNAs: novel players in cervical cancer

Javid Sadri Nahand et al.

EPIGENOMICS (2020)

添加到收藏夹

Review Oncology

Regulation of Glycolysis by Non-coding RNAs in Cancer: Switching on the Warburg Effect

Hamed Mirzaei et al.

MOLECULAR THERAPY-ONCOLYTICS (2020)

添加到收藏夹

Article Immunology

MicroRNA-16 directly binds to DEC2 and inactivates the TLR4 signaling pathway to inhibit lupus nephritis-induced kidney tissue hyperplasia and mesangial cell proliferation

Huimeng Qi et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Autophagy-related microRNAs: Possible regulatory roles and therapeutic potential in and gastrointestinal cancers

Mohammad Hossein Pourhanifeh et al.

PHARMACOLOGICAL RESEARCH (2020)

添加到收藏夹

Article Oncology

Serum exosomal miR-122 as a potential diagnostic and prognostic biomarker of colorectal cancer with liver metastasis

Li Sun et al.

JOURNAL OF CANCER (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Isoalantolactone suppresses LPS-induced inflammation by inhibiting TRAF6 ubiquitination and alleviates acute lung injury

Yun-he Ding et al.

ACTA PHARMACOLOGICA SINICA (2019)

添加到收藏夹

Article Immunology

MicroRNA-663 induces immune dysregulation by inhibiting TGF-β1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus

Linyu Geng et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2019)

添加到收藏夹

Article Medical Laboratory Technology

Association between miRNA-146a and Polymorphisms of its Target Gene, IRAK1, Regarding Susceptibility to and Clinical Features of Systemic Lupus Erythematous and Multiple Sclerosis

Dalia A. Labib et al.

LABORATORY MEDICINE (2019)

添加到收藏夹

Article Rheumatology

Associations of circulating cell-free microRNA with vasculopathy and vascular events in systemic lupus erythematosus patients

S. D. Kay et al.

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2019)

添加到收藏夹

Article Medical Laboratory Technology

Association between miRNA-146a and Polymorphisms of its Target Gene, IRAK1, Regarding Susceptibility to and Clinical Features of Systemic Lupus Erythematous and Multiple Sclerosis

Dalia A. Labib et al.

LABORATORY MEDICINE (2019)

添加到收藏夹

Article Cell Biology

MicroRNA-155 Suppresses Mesangial Cell Proliferation and TGF-1 Production via Inhibiting CXCR5-ERK Signaling Pathway in Lupus Nephritis

Jie Kong et al.

INFLAMMATION (2019)

添加到收藏夹

Article Cell Biology

MyD88 hypermethylation mediated by DNMT1 is associated with LTA-induced inflammatory response in human odontoblast-like cells

Runsha Meng et al.

CELL AND TISSUE RESEARCH (2019)

添加到收藏夹

Article Rheumatology

Downregulation of miR-633 activated AKT/mTOR pathway by targeting AKT1 in lupus CD4+ T cells

S. Chen et al.

LUPUS (2019)

添加到收藏夹

Article Cell Biology

Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex

Livia W. Brier et al.

MOLECULAR BIOLOGY OF THE CELL (2019)

添加到收藏夹

Editorial Material Medicine, Research & Experimental

Circular RNAS: novel biomarkers of disease activity in systemic lupus erythematosus?

Raquel Cortes et al.

CLINICAL SCIENCE (2019)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Identification of circular RNA Hsa_circ_0001879 and Hsa_circ_0004104 as novel biomarkers for coronary artery disease

Laiyuan Wang et al.

ATHEROSCLEROSIS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

MiR-199-3p promotes ERK-mediated IL-10 production by targeting poly (ADP-ribose) Polymerase-1 in patients with systemic lupus erythematosus

Xiaoping Su et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2019)

添加到收藏夹

Review Medicine, General & Internal

Novel paradigms in systemic lupus erythematosus

Thomas Doerner et al.

LANCET (2019)

添加到收藏夹

Article Immunology

MiR-183 delivery attenuates murine lupus nephritis-related injuries via targeting mTOR

Xiuzhen Li et al.

SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Circulating Exosomes Derived-miR-146a from Systemic Lupus Erythematosus Patients Regulates Senescence of Mesenchymal Stem Cells

Chen Dong et al.

BIOMED RESEARCH INTERNATIONAL (2019)

添加到收藏夹

Article Immunology

Excessive miR-152-3p Results in Increased BAFF Expression in SLE B-Cells by Inhibiting the KLF5 Expression

Shuangyan Luo et al.

FRONTIERS IN IMMUNOLOGY (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Differential Plasma Expression Profiles of Long Non-Coding RNAs Reveal Potential Biomarkers for Systemic Lupus Erythematosus

Guo-Cui Wu et al.

BIOMOLECULES (2019)

添加到收藏夹

Article Hematology

circMYBL2, a circRNA from MYBL2, regulates FLT3 translation by recruiting PTBP1 to promote FLT3-ITD AML progression

Yu-Meng Sun et al.

BLOOD (2019)

添加到收藏夹

Review Pharmacology & Pharmacy

Long Non-Coding RNAs as Epigenetic Regulators in Cancer

Asma Vafadar et al.

CURRENT PHARMACEUTICAL DESIGN (2019)

添加到收藏夹

Review Genetics & Heredity

The biogenesis, biology and characterization of circular RNAs

Lasse S. Kristensen et al.

NATURE REVIEWS GENETICS (2019)

添加到收藏夹

Article Immunology

MiRNA Regulation of MIF in SLE and Attenuation of Murine Lupus Nephritis With miR-654

Yang Tu et al.

FRONTIERS IN IMMUNOLOGY (2019)

添加到收藏夹

Article Fisheries

Myeloid differentiation factor 88 (Myd88) is involved in the innate immunity of black carp (Mylopharyngodon piceus) defense against pathogen infection

Xueshu Zhang et al.

FISH & SHELLFISH IMMUNOLOGY (2019)

添加到收藏夹

Review Genetics & Heredity

miRNAs derived from cancer-associated fibroblasts in colorectal cancer

Amir Savardashtaki et al.

EPIGENOMICS (2019)

添加到收藏夹

Review Reproductive Biology

Circular RNAs in cancer: new insights into functions and implications in ovarian cancer

Zahra Shabaninejad et al.

JOURNAL OF OVARIAN RESEARCH (2019)

添加到收藏夹

Review Cell & Tissue Engineering

Mesenchymal stem cell-derived exosomes: a new therapeutic approach to osteoarthritis?

Elaheh Mianehsaz et al.

STEM CELL RESEARCH & THERAPY (2019)

添加到收藏夹

Article Immunology

miR-98 Modulates Cytokine Production from Human PBMCs in Systemic Lupus Erythematosus by Targeting IL-6 mRNA

Shiwen Yuan et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2019)

添加到收藏夹

Article Genetics & Heredity

Association between changes in gene signatures expression and disease activity among patients with systemic lupus erythematosus

Michelle Petri et al.

BMC MEDICAL GENOMICS (2019)

添加到收藏夹

Article Rheumatology

Elevated expression of miR-21 and miR-155 in peripheral blood mononuclear cells as potential biomarkers for lupus nephritis

Majid Khoshmirsafa et al.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES (2019)

添加到收藏夹

Review Cell Biology

Molecular aspects of pancreatic β-cell dysfunction: Oxidative stress, microRNA, and long noncoding RNA

Mohammad Javad Saeedi Borujeni et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Genetic and epigenetic contribution to astrocytic gliomas pathogenesis

Pouria Khani et al.

JOURNAL OF NEUROCHEMISTRY (2019)

添加到收藏夹

Article Medicine, Research & Experimental

TRAF6 neddylation drives inflammatory arthritis by increasing NF-κB activation

Kewei Liu et al.

LABORATORY INVESTIGATION (2019)

添加到收藏夹

Editorial Material Rheumatology

Selective Janus kinase inhibitors come of age

John J. O'Shea et al.

NATURE REVIEWS RHEUMATOLOGY (2019)

添加到收藏夹

Article Immunology

miR-152 Attenuates the Severity of Lupus Nephritis Through the Downregulation of Macrophage Migration Inhibitory Factor (MIF)-Induced Expression of COL1A1

Jiayi Zheng et al.

FRONTIERS IN IMMUNOLOGY (2019)

添加到收藏夹

Article Physiology

MicroRNA-145 Involves in the Pathogenesis of Renal Vascular Lesions and May Become a Potential Therapeutic Target in Patients with Juvenile Lupus Nephritis

Zhaomin Cai et al.

KIDNEY & BLOOD PRESSURE RESEARCH (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases

Shruti Mishra et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2019)

添加到收藏夹

Article Rheumatology

LNA-anti-miR-150 ameliorated kidney injury of lupus nephritis by inhibiting renal fibrosis and macrophage infiltration

Junjun Luan et al.

ARTHRITIS RESEARCH & THERAPY (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Highlighted STAT3 as a potential drug target for cancer therapy

Haeri Lee et al.

BMB REPORTS (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

MicroRNAs as Diagnostic, Prognostic, and Therapeutic Biomarkers in Prostate Cancer

Arad Mobasher Aghdam et al.

CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION (2019)

添加到收藏夹

Article Medicine, General & Internal

miR-210 expression in PBMCs from patients with systemic lupus erythematosus and rheumatoid arthritis

Q. Huang et al.

IRISH JOURNAL OF MEDICAL SCIENCE (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Oral tumors in children: Diagnosis and management

Razieh Khanmohammadi et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

MiR-21: A key player in glioblastoma pathogenesis

Mohammad Sadegh Masoudi et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Molecular aspects of diabetes mellitus: Resistin, microRNA, and exosome

Mohammad Javad Saeedi Borujeni et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

添加到收藏夹

Review Cell Biology

Apelin/APJ system: A novel potential therapy target for kidney disease

Zhen Huang et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

添加到收藏夹

Article Rheumatology

EZH2 Modulates the DNA Methylome and Controls T Cell Adhesion Through Junctional Adhesion Molecule A in Lupus Patients

Pei-Suen Tsou et al.

ARTHRITIS & RHEUMATOLOGY (2018)

添加到收藏夹

Article Rheumatology

DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

Juliana Imgenberg-Kreuz et al.

ANNALS OF THE RHEUMATIC DISEASES (2018)

添加到收藏夹

Article Medicine, Research & Experimental

miR-125b is downregulated in systemic lupus erythematosus patients and inhibits autophagy by targeting UVRAG

Wenting Cao et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

添加到收藏夹

Review Oncology

The emerging functions and roles of circular RNAs in cancer

Shibin Qu et al.

CANCER LETTERS (2018)

添加到收藏夹

Article Oncology

SHP-1 Acts as a Tumor Suppressor in Hepatocarcinogenesis and HCC Progression

Liang-Zhi Wen et al.

CANCER RESEARCH (2018)

添加到收藏夹

Review Medical Laboratory Technology

Review: Apelin in disease

Hanna Antushevich et al.

CLINICA CHIMICA ACTA (2018)

添加到收藏夹

Review Rheumatology

Epidemiology of systemic lupus erythematosus: an update

George Stojan et al.

CURRENT OPINION IN RHEUMATOLOGY (2018)

添加到收藏夹

Review Oncology

Inhibition of miR-135b by SP-1 promotes hypoxia-induced vascular endothelial cell injury via HIF-1α

Songbai Yang et al.

EXPERIMENTAL CELL RESEARCH (2018)

添加到收藏夹

Review Cell Biology

Circulating microRNAs as diagnostic and therapeutic biomarkers in gastric and esophageal cancers

Leila Jamali et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

添加到收藏夹

Article Rheumatology

Role of MiR-98 and Its Underlying Mechanisms in Systemic Lupus Erythematosus

Lin Xie et al.

JOURNAL OF RHEUMATOLOGY (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer

Ying Zhang et al.

MOLECULAR CANCER (2018)

添加到收藏夹

Article Rheumatology

microRNA downregulation in plasmacytoid dendritic cells in interferon-positive systemic lupus erythematosus and antiphospholipid syndrome

Lucas L. van den Hoogen et al.

RHEUMATOLOGY (2018)

添加到收藏夹

Article Medicine, Research & Experimental

circHLA-C Plays an Important Role in Lupus Nephritis by Sponging miR-150

Junjun Luan et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2018)

添加到收藏夹

Article Medicine, Research & Experimental

MicroRNA-326 Upregulates B Cell Activity and Autoantibody Production in Lupus Disease of MRL/lpr Mice

Yuan Xia et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

The expression levels of long noncoding RNAs lnc0640 and lnc5150 and its gene single-nucleotide polymorphisms in rheumatoid arthritis patients

Tian-Ping Zhang et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

添加到收藏夹

Article Immunology

Serum miRNA-371b-5p and miRNA-5100 act as biomarkers for systemic lupus erythematosus

Li Zeng et al.

CLINICAL IMMUNOLOGY (2018)

添加到收藏夹

Article Oncology

Inhibition of microRNA-182-5p contributes to attenuation of lupus nephritis via Foxo1 signaling

Xiaoyang Wang et al.

EXPERIMENTAL CELL RESEARCH (2018)

添加到收藏夹

Article Rheumatology

Increased CD4(+)CD25(-)Foxp3(+) T cells in Chinese systemic lupus erythematosus: correlate with disease activity and organ involvement

Z-J Yin et al.

LUPUS (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

microRNA-199a may be involved in the pathogenesis of lupus nephritis via modulating the activation of NF-kappa B by targeting Klotho

Hong Ye et al.

MOLECULAR IMMUNOLOGY (2018)

添加到收藏夹

Letter Oncology

Circulating miR-21 as novel biomarker in gastric cancer: Diagnostic and prognostic biomarker

Miganoosh Simonian et al.

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS (2018)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

IL-1R and MyD88 signalling in CD4(+) T cells promote Th17 immunity and atherosclerosis

Daniel Engelbertsen et al.

CARDIOVASCULAR RESEARCH (2018)

添加到收藏夹

Article Rheumatology

A polymorphism upstream MIR1279 gene is associated with pericarditis development in Systemic Lupus Erythematosus and contributes to definition of a genetic risk profile for this complication

C. Ciccacci et al.

LUPUS (2017)

添加到收藏夹

Review Neurosciences

Circular RNAs: the Emerging Class of Non-coding RNAs and Their Potential Role in Human Neurodegenerative Diseases

Lalit Kumar et al.

MOLECULAR NEUROBIOLOGY (2017)

添加到收藏夹

Review Immunology

Epidemiology of systemic lupus erythematosus

Guillermo J. Pons-Estel et al.

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2017)

添加到收藏夹

Article Cell Biology

Reduction of CD19 autoimmunity marker on B cells of paediatric SLE patients through repressing PU.1/TNF-α/BAFF axis pathway by miR-155

H. R. Aboelenein et al.

GROWTH FACTORS (2017)

添加到收藏夹

Article Cell Biology

miRNA-451a Targets IFN Regulatory Factor 8 for the Progression of Systemic Lupus Erythematosus

Jia Cheng et al.

INFLAMMATION (2017)

添加到收藏夹

Article Rheumatology

Unraveling the expression of microRNA-27a*& NKG2D in peripheral blood mononuclear cells and natural killer cells of pediatric systemic lupus erythematosus patients

Shady K. Sourour et al.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES (2017)

添加到收藏夹

Article Immunology

MicroRNA-302d targets IRF9 to regulate the IFN-induced gene expression in SLE

Siobhan Smith et al.

JOURNAL OF AUTOIMMUNITY (2017)

添加到收藏夹

Article Immunology

Expression of long non-coding RNAs in autoimmunity and linkage to enhancer function and autoimmune disease risk genetic variants

T. M. Aune et al.

JOURNAL OF AUTOIMMUNITY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Stroke in Women: Risk Factors and Clinical Biomarkers

Hamed Mirzaei

JOURNAL OF CELLULAR BIOCHEMISTRY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

MicroRNAs-Based Imaging Techniques in Cancer Diagnosis and Therapy

Maryam Keshavarzi et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Molecular Imaging and Oral Cancer Diagnosis and Therapy

Maryam Keshavarzi et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2017)

添加到收藏夹

Article Dermatology

Ultraviolet B inhibition of DNMT1 activity via AhR activation dependent SIRT1 suppression in CD4+T cells from systemic lupus erythematosus patients

Zhouwei Wu et al.

JOURNAL OF DERMATOLOGICAL SCIENCE (2017)

添加到收藏夹

Article Immunology

Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells

Eri Katsuyama et al.

JOURNAL OF IMMUNOLOGY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

Ivano Legnini et al.

MOLECULAR CELL (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Enhanced expression of TREM-1 in splenic cDCs in lupus prone mice and it was modulated by miRNA-150

Sheng Gao et al.

MOLECULAR IMMUNOLOGY (2017)

添加到收藏夹

Article Oncology

MicroRNA-198 contributes to lupus nephritis progression by inhibition of phosphatase and tensin homology deleted on chromosome ten expression

Danyu Cui et al.

MOLECULAR MEDICINE REPORTS (2017)

添加到收藏夹

Article Pharmacology & Pharmacy

Dysregulation of miRNA-146a contributes to the development of lupus nephritis via targeting of TRAF6

Shupeng Wu et al.

PERSONALIZED MEDICINE (2017)

添加到收藏夹

Article Multidisciplinary Sciences

miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression

Nathaniel Magilnick et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

添加到收藏夹

Review Rheumatology

The worldwide incidence and prevalence of systemic lupus erythematosus: a systematic review of epidemiological studies

Frances Rees et al.

RHEUMATOLOGY (2017)

添加到收藏夹

Article Rheumatology

Epigenetic Variability in Systemic Lupus Erythematosus: What We Learned from Genome-Wide DNA Methylation Studies

Maria Teruel et al.

CURRENT RHEUMATOLOGY REPORTS (2017)

添加到收藏夹

Article Medicine, Research & Experimental

Regulation of MiR-146a and TRAF6 in the Diagnose of Lupus Nephritis

Yunfeng Zhu et al.

MEDICAL SCIENCE MONITOR (2017)

添加到收藏夹

Article Immunology

Dysregulation of miR-155-5p and miR-200-3p and the Anti-Non-Bilayer Phospholipid Arrangement Antibodies Favor the Development of Lupus in Three Novel Murine Lupus Models

Luz Angela Zarate-Neira et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2017)

添加到收藏夹

Article Multidisciplinary Sciences

MicroRNA 155-deficiency leads to decreased autoantibody levels and reduced severity of nephritis and pneumonitis in pristaneinduced lupus

Harald Leiss et al.

PLOS ONE (2017)

添加到收藏夹

Article Cell Biology

Microarray Expression Profile of Circular RNAs in Peripheral Blood Mononuclear Cells from Rheumatoid Arthritis Patients

Qingqing Ouyang et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

添加到收藏夹

Article Medicine, General & Internal

46-Year Trends in Systemic Lupus Erythematosus Mortality in the United States, 1968 to 2013 A Nationwide Population-Based Study

Eric Y. Yen et al.

ANNALS OF INTERNAL MEDICINE (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Elevated expression of microRNA-873 facilitates Th17 differentiation by targeting forkhead box O1 (Foxo1) in the pathogenesis of systemic lupus erythematosus

Lining Liu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)

添加到收藏夹

Article Medical Laboratory Technology

Identification, Confirmation, and Replication of Novel Urinary MicroRNA Biomarkers in Lupus Nephritis and Diabetic Nephropathy

Mariana Cardenas-Gonzalez et al.

CLINICAL CHEMISTRY (2017)

添加到收藏夹

Review Rheumatology

Genetic advances in systemic lupus erythematosus: an update

Lingyan Chen et al.

CURRENT OPINION IN RHEUMATOLOGY (2017)

添加到收藏夹

Article Immunology

Activation of TLR7 increases CCND3 expression via the downregulation of miR-15b in B cells of systemic lupus erythematosus

Deshan Ren et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2016)

添加到收藏夹

Article Transplantation

Micro-RNA analysis of renal biopsies in human lupus nephritis demonstrates up-regulated miR-422a driving reduction of kallikrein-related peptidase 4

Eleni Krasoudaki et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2016)

添加到收藏夹

Article Cell Biology

miR-148a-3p overexpression contributes to glomerular cell proliferation by targeting PTEN in lupus nephritis

Liu Qingjuan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)

添加到收藏夹

Article Rheumatology

IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus

Ming Zhao et al.

ANNALS OF THE RHEUMATIC DISEASES (2016)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Integrated analysis of mRNA, microRNA and protein in systemic lupus erythematosus-specific induced pluripotent stem cells from urine

Donge Tang et al.

BMC GENOMICS (2016)

添加到收藏夹

Article Cell Biology

MiR-410 Down-Regulates the Expression of Interleukin-10 by Targeting STAT3 in the Pathogenesis of Systemic Lupus Erythematosus

Dongmei Liu et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2016)

添加到收藏夹

Review Medical Laboratory Technology

The apelin-APJ axis: A novel potential therapeutic target for organ fibrosis

Shifang Huang et al.

CLINICA CHIMICA ACTA (2016)

添加到收藏夹

Article Rheumatology

Overall and cause-specific mortality in systemic lupus erythematosus: an updated meta-analysis

Y. H. Lee et al.

LUPUS (2016)

添加到收藏夹

Article Oncology

Hsa-miR-371-5p inhibits human mesangial cell proliferation and promotes apoptosis in lupus nephritis by directly targeting hypoxia-inducible factor 1α

Feifei Yao et al.

MOLECULAR MEDICINE REPORTS (2016)

添加到收藏夹

Review Rheumatology

New insights into the immunopathogenesis of systemic lupus erythematosus

George C. Tsokos et al.

NATURE REVIEWS RHEUMATOLOGY (2016)

添加到收藏夹

Article Rheumatology

The role of microRNA-31 and microRNA-21 as regulatory biomarkers in the activation of T lymphocytes of Egyptian lupus patients

Khalda Sayed Amr et al.

RHEUMATOLOGY INTERNATIONAL (2016)

添加到收藏夹

Article Rheumatology

Epigenetic Reprogramming in Naive CD4+T Cells Favoring T Cell Activation and Non-Th1 Effector T Cell Immune Response as an Early Event in Lupus Flares

Patrick Coit et al.

ARTHRITIS & RHEUMATOLOGY (2016)

添加到收藏夹

Review Neurosciences

Roles of Circular RNAs in Neurologic Disease

Yiye Shao et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2016)

添加到收藏夹

Article Genetics & Heredity

Mini Review: Circular RNAs as Potential Clinical Biomarkers for Disorders in the Central Nervous System

Dan Lu et al.

Frontiers in Genetics (2016)

添加到收藏夹

Article Cell Biology

Circulating hsa-miR-30e-5p, hsa-miR-92a-3p, and hsa-miR-223-3p may be novel biomarkers in systemic lupus erythematosus

B. -S. Kim et al.

HLA (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Urinary Exosomal miRNA Signature in Type II Diabetic Nephropathy Patients

Denis Delic et al.

PLOS ONE (2016)

添加到收藏夹

Review Oncology

Circular RNA: A new star of noncoding RNAs

Shibin Qu et al.

CANCER LETTERS (2015)

添加到收藏夹

Article Medicine, General & Internal

Circulating and urinary microRNA profile in focal segmental glomerulosclerosis: a pilot study

Ali Ramezani et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2015)

添加到收藏夹

Review Immunology

Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system

Matthew C. Walsh et al.

IMMUNOLOGICAL REVIEWS (2015)

添加到收藏夹

Review Biochemistry & Molecular Biology

Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus

Kongyang Ma et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

添加到收藏夹

Article Immunology

miR-155 Deficiency Ameliorates Autoimmune Inflammation of Systemic Lupus Erythematosus by Targeting S1pr1 in Faslprlpr Mice

Qian Xin et al.

JOURNAL OF IMMUNOLOGY (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Increased Urinary Exosomal MicroRNAs in Patients with Systemic Lupus Erythematosus

Javier Perez-Hernandez et al.

PLOS ONE (2015)

添加到收藏夹

Article Oncology

The role of microRNA-1246 in the regulation of B cell activation and the pathogenesis of systemic lupus erythematosus

Shuangyan Luo et al.

CLINICAL EPIGENETICS (2015)

添加到收藏夹

Article Rheumatology

The Role of MicroRNAs and Human Epidermal Growth Factor Receptor 2 in Proliferative Lupus Nephritis

Patricia Costa-Reis et al.

ARTHRITIS & RHEUMATOLOGY (2015)

添加到收藏夹

Article Rheumatology

Type I Interferon Inhibition of MicroRNA-146a Maturation Through Up-Regulation of Monocyte Chemotactic Protein-Induced Protein 1 in Systemic Lupus Erythematosus

Bo Qu et al.

ARTHRITIS & RHEUMATOLOGY (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Let-7 miRNAs Modulate the Activation of NF-κB by Targeting TNFAIP3 and Are Involved in the Pathogenesis of Lupus Nephritis

Jun Liu et al.

PLOS ONE (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Up-regulation of Serum MiR-130b-3p Level is Associated with Renal Damage in Early Lupus Nephritis

Wanpeng Wang et al.

SCIENTIFIC REPORTS (2015)

添加到收藏夹

Article Urology & Nephrology

Hypoxia Inducible Factor-1 Alpha Promotes Mesangial Cell Proliferation in Lupus Nephritis

Wei Deng et al.

AMERICAN JOURNAL OF NEPHROLOGY (2014)

添加到收藏夹

Article Medical Laboratory Technology

Comparison of serum exosome isolation methods for microRNA profiling

Kadri Rekker et al.

CLINICAL BIOCHEMISTRY (2014)

添加到收藏夹

Article Rheumatology

High expression levels of microRNA-629, microRNA-525-5p and microRNA-516a-3p in paediatric systemic lupus erythematosus

Jia Zhu et al.

CLINICAL RHEUMATOLOGY (2014)

添加到收藏夹

Review Pharmacology & Pharmacy

Exosomes as Immunotheranostic Nanoparticles

G. Natasha et al.

CLINICAL THERAPEUTICS (2014)

添加到收藏夹

Article Gastroenterology & Hepatology

Discovery of Novel Src Homology Region 2 Domain-Containing Phosphatase 1 Agonists From Sorafenib for the Treatment of Hepatocellular Carcinoma

Wei-Tien Tai et al.

HEPATOLOGY (2014)

添加到收藏夹

Review Immunology

HIF Transcription Factors, Inflammation, and Immunity

Asis Palazon et al.

IMMUNITY (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

miRNA in Plasma Exosome is Stable under Different Storage Conditions

Qinyu Ge et al.

MOLECULES (2014)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Detecting and characterizing circular RNAs

William R. Jeck et al.

NATURE BIOTECHNOLOGY (2014)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification

Jeffrey J. Quinn et al.

NATURE BIOTECHNOLOGY (2014)

添加到收藏夹

Article Cell Biology

Defective PTEN regulation contributes to B cell hyperresponsiveness in systemic lupus erythematosus

Xiang-ni Wu et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

添加到收藏夹

Article Rheumatology

MicroRNA-146a in autoimmunity and innate immune responses

Edward K. L. Chan et al.

ANNALS OF THE RHEUMATIC DISEASES (2013)

添加到收藏夹

Article Immunology

Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesis

M-C. Lu et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2013)

添加到收藏夹

Article Immunology

Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function

Eoin N. McNamee et al.

IMMUNOLOGIC RESEARCH (2013)

添加到收藏夹

Article Immunology

E4BP4 overexpression: A protective mechanism in CD4(+) T cells from SLE patients

Ming Zhao et al.

JOURNAL OF AUTOIMMUNITY (2013)

添加到收藏夹

Article Dermatology

MicroRNA-29b contributes to DNA hypomethylation of CD4+T cells in systemic lupus erythematosus by indirectly targeting DNA methyltransferase 1

Haihong Qin et al.

JOURNAL OF DERMATOLOGICAL SCIENCE (2013)

添加到收藏夹

Article Urology & Nephrology

miR-150 Promotes Renal Fibrosis in Lupus Nephritis by Downregulating SOCS1

Hua Zhou et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Natural RNA circles function as efficient microRNA sponges

Thomas B. Hansen et al.

NATURE (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Circular RNAs are a large class of animal RNAs with regulatory potency

Sebastian Memczak et al.

NATURE (2013)

添加到收藏夹

Editorial Material Biochemistry & Molecular Biology

From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition

Riccardo Taulli et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)

添加到收藏夹

Article Medicine, General & Internal

Genetic Associations with Valvular Calcification and Aortic Stenosis

George Thanassoulis et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

添加到收藏夹

Article Rheumatology

Dual downregulation of microRNA 17-5p and E2F1 transcriptional factor in pediatric systemic lupus erythematosus patients

Heba Ragaee Abdelhakam Aboelenein et al.

RHEUMATOLOGY INTERNATIONAL (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

Carolina Villarroya-Beltri et al.

NATURE COMMUNICATIONS (2013)

添加到收藏夹

Article Rheumatology

Identification of microRNA-31 as a novel regulator contributing to impaired interleukin-2 production in T cells from patients with systemic lupus erythematosus

Wei Fan et al.

ARTHRITIS AND RHEUMATISM (2012)

添加到收藏夹

Article Oncology

A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation

Kuen-Feng Chen et al.

CANCER LETTERS (2012)

添加到收藏夹

Article Chemistry, Medicinal

Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity

Kuen-Feng Chen et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)

添加到收藏夹

Article Medical Laboratory Technology

microRNA146a Expression in Lupus Patients With and Without Renal Complications

D. Hashad et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2012)

添加到收藏夹

Article Urology & Nephrology

Altered expression of microRNA miR-146a correlates with the development of chronic renal inflammation

Osamu Ichii et al.

KIDNEY INTERNATIONAL (2012)

添加到收藏夹

Article Medical Laboratory Technology

Circulating microRNAs as candidate biomarkers in patients with systemic lupus erythematosus

Honglei Wang et al.

TRANSLATIONAL RESEARCH (2012)

添加到收藏夹

Review Immunology

E4BP4: an unexpected player in the immune response

Victoria Male et al.

TRENDS IN IMMUNOLOGY (2012)

添加到收藏夹

Article Rheumatology

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression

Elias Stagakis et al.

ANNALS OF THE RHEUMATIC DISEASES (2011)

添加到收藏夹

Article Rheumatology

MicroRNA-126 Regulates DNA Methylation in CD4+T Cells and Contributes to Systemic Lupus Erythematosus by Targeting DNA Methyltransferase 1

Sha Zhao et al.

ARTHRITIS AND RHEUMATISM (2011)

添加到收藏夹

Article Biochemistry & Molecular Biology

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

Eric V. Dang et al.

CELL (2011)

添加到收藏夹

Article Medicine, Research & Experimental

Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice

Barry G. Garchow et al.

EMBO MOLECULAR MEDICINE (2011)

添加到收藏夹

Article Immunology

HIF1α-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

Lewis Z. Shi et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2011)

添加到收藏夹

Article Immunology

miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice

Mark P. Boldin et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2011)

添加到收藏夹

Article Immunology

Dicer Insufficiency and MicroRNA-155 Overexpression in Lupus Regulatory T Cells: An Apparent Paradox in the Setting of an Inflammatory Milieu

Anagha A. Divekar et al.

JOURNAL OF IMMUNOLOGY (2011)

添加到收藏夹

Article Medicine, Research & Experimental

Body fluid derived exosomes as a novel template for clinical diagnostics

Sascha Keller et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2011)

添加到收藏夹

Article Rheumatology

Serum and urinary free microRNA level in patients with systemic lupus erythematosus

G. Wang et al.

LUPUS (2011)

添加到收藏夹

Review Urology & Nephrology

Cellular and molecular mechanisms of renal fibrosis

Youhua Liu

NATURE REVIEWS NEPHROLOGY (2011)

添加到收藏夹

Review Medicine, General & Internal

MECHANISMS OF DISEASE Systemic Lupus Erythematosus

George C. Tsokos

NEW ENGLAND JOURNAL OF MEDICINE (2011)

添加到收藏夹

Review Rheumatology

MicroRNAs in systemic rheumatic diseases

Angela Ceribelli et al.

ARTHRITIS RESEARCH & THERAPY (2011)

添加到收藏夹

Review Immunology

Monocyte and Macrophage Abnormalities in Systemic Lupus Erythematosus

Yi Li et al.

ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2010)

添加到收藏夹

Article Rheumatology

MicroRNA-125a Contributes to Elevated Inflammatory Chemokine RANTES Levels via Targeting KLF13 in Systemic Lupus Erythematosus

Xia Zhao et al.

ARTHRITIS AND RHEUMATISM (2010)

添加到收藏夹

Article Immunology

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

Wen Pan et al.

JOURNAL OF IMMUNOLOGY (2010)

添加到收藏夹

Article Multidisciplinary Sciences

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

Munekazu Yamakuchi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

添加到收藏夹

Article Rheumatology

Lack of association between the interferon-α signature and longitudinal changes in disease activity in systemic lupus erythematosus

C. Landolt-Marticorena et al.

ANNALS OF THE RHEUMATIC DISEASES (2009)

添加到收藏夹

Article Rheumatology

MicroRNA-146a Contributes to Abnormal Activation of the Type I Interferon Pathway in Human Lupus by Targeting the Key Signaling Proteins

Yuanjia Tang et al.

ARTHRITIS AND RHEUMATISM (2009)

添加到收藏夹

Article Immunology

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

Shintaro Kamizono et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2009)

添加到收藏夹

Article Immunology

The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development

Duncan M. Gascoyne et al.

NATURE IMMUNOLOGY (2009)

添加到收藏夹

Review Physiology

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

Gregg L. Semenza

PHYSIOLOGY (2009)

添加到收藏夹

Article Cell Biology

MiR-126 regulates angiogenic signaling and vascular integrity

Jason E. Fish et al.

DEVELOPMENTAL CELL (2008)

添加到收藏夹

Article Multidisciplinary Sciences

Gene-specific control of inflammation by TLR-induced chromatin modifications

Simmie L. Foster et al.

NATURE (2007)

添加到收藏夹

Article Rheumatology

An assessment of renal failure in an SLE cohort with special reference to ethnicity, over a 25-year period

M. Adler et al.

RHEUMATOLOGY (2006)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.