4.8 Article

Scalable Synthesis of Silacyclohexanones and Ready Access to Silicon Building Blocks

期刊

ORGANIC LETTERS
卷 -, 期 -, 页码 -

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.3c02561

关键词

-

向作者/读者索取更多资源

A simple and efficient two-step method for the synthesis of silacyclohexanones using TosMIC is presented. The prepared silacyclohexanones were transformed into various heterocycles with silicon incorporation. Additionally, the method was successfully applied to the synthesis of a sila analogue of the HDAC6 inhibitor tubastatin A.
A simple and efficient two-step method for the synthesis of silacyclohexanones starting from bis(bromoethylsilanes) using TosMIC is presented. The prepared silacyclohexanones were transformed to nine different heterocycles with silicon incorporation. In addition, the developed methodology was used for the synthesis of a sila analogue of the HDAC6 inhibitor tubastatin A.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据