期刊
ORGANIC LETTERS
卷 25, 期 31, 页码 5916-5921出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.3c02293
关键词
-
A copper-catalyzed trifluoromethylthio-arylsulfonylation reaction is presented, which allows for the introduction of sulfone, SCF3, and allene moieties into one molecule simultaneously. This strategy offers mild reaction conditions, good substrate compatibility, and excellent regioselectivity. The resulting products have the potential for further conversion into valuable compounds. Initial investigations suggest a radical pathway for the reaction mechanism, and the SOgen used in this transformation is proven to be an uniquely effective SO2 surrogate.
A copper-catalyzed trifluoromethylthio-arylsulfonylationbetween1,3-enynes, AgSCF3, aryldiazonium tetrafluoroborates, andSO(2) (from SOgen) is presented, which could introduce sulfone,SCF3, and allene moieties into one molecule simultaneously.This strategy features mild reaction conditions, good substrate compatibility,and excellent regioselectivity. The products obtained have the potentialfor further conversion into other valuable compounds. Initial investigationsinto the reaction mechanism suggest that it may proceed via a radicalpathway. Notably, SOgen was proven as a uniquely effective SO2 surrogate in this transformation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据