Scientific evidence of foods that improve the lifespan and healthspan of different organisms

Age is a risk factor for numerous diseases. Although the development of modern medicine has greatly extended the human lifespan, the duration of relatively healthy old age, or 'healthspan', has not increased. Targeting the detrimental processes that can occur before the onset of age-related diseases can greatly improve health and lifespan. Healthspan is significantly affected by what, when and how much one eats. Dietary restriction, including calorie restriction, fasting or fasting-mimicking diets, to extend both lifespan and healthspan has recently attracted much attention. However, direct scientific evidence that consuming specific foods extends the lifespan and healthspan seems lacking. Here, we synthesized the results of recent studies on the lifespan and healthspan extension properties of foods and their phytochemicals in various organisms to confirm how far the scientific research on the effect of food on the lifespan has reached.

Automated summary

Age is a risk factor for diseases, and prolonging healthspan is important. Dietary restriction, such as calorie restriction and fasting, has received attention for its potential to extend lifespan and healthspan. However, scientific evidence on specific foods' effects on lifespan and healthspan is lacking. This study aims to synthesize recent research on the effects of foods and phytochemicals on lifespan and healthspan.