Reflecting the causes of variability of EEG responses elicited by cerebellar TMS

Recently, Fong et al. published EEG responses in cerebral cortex elicited by cerebellar TMS (cbTMS) (Fong et al., 2023), which differ from our recently identified cbTMS-EEG responses (Gassmann et al., 2022). Fong et al. argued that this discrepancy is due to coil placement unsuitable for eliciting cerebellar brain inhibition (CBI) in our study. However, we reliably elicited CBI in our subjects. Consequently, this leads to a compelling discussion on possible reasons for the observed discrepancies in cbTMS-evoked EEG responses. Reliably measuring cbTMSevoked EEG responses could become an important neurophysiological tool to test effective cerebellum-to-cortex connectivity.

Automated summary

Recently, discrepancies were found in EEG responses in the cerebral cortex elicited by cerebellar TMS. The authors discussed possible reasons for the observed differences and highlighted the significance of reliably measuring cbTMS-evoked EEG responses in testing cerebellum-to-cortex connectivity.