Burst Suppression as a Treatment Goal in Refractory Status Epilepticus

Article Clinical Neurology

Association Between Induced Burst Suppression and Clinical Outcomes in Patients With Refractory Status Epilepticus A 9-Year Cohort Study

Urs Fisch et al.

Summary: This study aimed to investigate the frequency of induced EEG burst suppression pattern during continuous IV anesthesia (IVAD) and its associated outcomes in adult patients treated for refractory status epilepticus (RSE). It was found that incomplete burst suppression occurred in 14% of patients without cerebral anoxia, while complete burst suppression occurred in 21% of patients. No association was found between burst suppression and outcomes in patients without cerebral anoxia, but in patients with cerebral anoxia, induced burst suppression was associated with persistent seizure termination and higher survival rate.

NEUROLOGY (2023)

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Editorial Material Critical Care Medicine

The Origin of the Burst-Suppression Paradigm in Treatment of Status Epilepticus

Maximiliano A. Hawkes et al.

Summary: Burst-suppression pattern (BSP) is a distinctive EEG pattern associated with coma, epileptic encephalopathies, and induced by general anesthesia and hypothermia. Research has explored the correlation between depth of EEG suppression and improved seizure control and clinical outcomes. From a historical perspective, the evidence for suppressing the brain to a BSP when treating status epilepticus is inconclusive.

NEUROCRITICAL CARE (2023)

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Article Critical Care Medicine

Teaching Important Basic EEG Patterns of Bedside Electroencephalography to Critical Care Staffs: A Prospective Multicenter Study

Stephane Legriel et al.

Summary: A training program consisting of face-to-face EEG courses and e-learning was effective in helping critical care staff accurately recognize important basic EEG patterns. The majority of participants achieved a success rate of at least 80% correct answers at day 90, showing a significant increase in knowledge and skills over time. Challenges still exist in correctly identifying some specific EEG patterns, indicating areas for potential improvement in training strategies.

NEUROCRITICAL CARE (2021)

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Article Clinical Neurology