4.5 Review

Scientific Landscape of Oxidative Stress in Stroke: From a Bibliometric Analysis to an in-Depth Review

期刊

NEUROCHEMICAL RESEARCH
卷 48, 期 11, 页码 3327-3348

出版社

SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s11064-023-03999-5

关键词

Stroke; Oxidative stress; Reactive Oxygen Species; Bibliometric; NLRP3 inflammasome; Ferroptosis

向作者/读者索取更多资源

Stroke is an acute cerebrovascular disease caused by blood vessel obstruction or rupture in the brain. Oxidative stress (OS), defined as a state where cellular oxidative capacities overpower antioxidative defenses, plays a role in stroke pathophysiology. This bibliometric analysis and in-depth review depict the research trend of OS in stroke. China and the United States are prominent in this field, as shown by their high publication counts and collaborations. Current key research areas include neuroinflammation, interaction among cell death mechanisms, and the association between air pollution and stroke.
Stroke is an acute cerebrovascular disease resulting from either obstruction or rupture of a blood vessel in the brain. Oxidative stress (OS), referred to a status where cellular oxidative capacities overwhelm antioxidative defenses, is involved in the pathophysiology of stroke. The bibliometric analysis and in-depth review aim to depict the research trend of OS in stroke. Relevant scientific publications were acquired from the Web of Science Core Collection database. Scientific landscape of OS in stroke was illustrated by general quantitative trend, impactful journals, and co-authorship of various academic units (i.e., countries/regions, organizations, and authors). Furthermore, theme analysis predicting the hot research issues and frontiers was performed. 15,826 documents regarding OS in stroke were obtained over a time span of more than 20 years from 1992 to 2021. The overall tendency of publication counts was continuously on the rise. Bibliometric analysis indicated China and the United States were predominant in this study field, as reflected by their high publication counts and intensive collaboration with other countries. Current key research areas of OS in stroke may lie in the investigation of neuroinflammation, and interaction among multiple cell death mechanisms including apoptosis, autophagy, and ferroptosis to search for effective treatments. Moreover, another hot topic could be the association between air pollution and stroke, and its underlying mechanisms. As the exploration of OS in stroke is speculated to be a continuous hot spot in the future, this article may be helpful for researchers to conduct future studies with the understanding of influential academic forces and research highlights.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据