4.6 Article

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

p70 S6 Kinase and Tau in Alzheimer's Disease

Jin-Jing Pei et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Article Geriatrics & Gerontology

How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story

Arlan Richardson et al.

EXPERIMENTAL GERONTOLOGY (2015)

Review Multidisciplinary Sciences

The role of protein clearance mechanisms in organismal ageing and age-related diseases

David Vilchez et al.

NATURE COMMUNICATIONS (2014)

Article Biochemistry & Molecular Biology

Over-expression of PRAS40 enhances insulin sensitivity in skeletal muscle

Claudia Wiza et al.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2014)

Review Multidisciplinary Sciences

mTOR is a key modulator of ageing and age-related disease

Simon C. Johnson et al.

NATURE (2013)

Article Multidisciplinary Sciences

Use of an Eight-arm Radial Water Maze to Assess Working and Reference Memory Following Neonatal Brain Injury

Stephanie C. Penley et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2013)

Article Neurosciences

Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s disease

Sharon C Yates et al.

Acta Neuropathologica Communications (2013)

Article Transplantation

Everolimus-induced Lymphedema in a Renal Transplant Recipient: A Case Report

Alparslan Ersoy et al.

EXPERIMENTAL AND CLINICAL TRANSPLANTATION (2012)

Article Medicine, Research & Experimental

Lymphedema of the Breast as a Symptom of Internal Diseases or Side Effect of mTor Inhibitors

U. Hille et al.

LYMPHATIC RESEARCH AND BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Activation of a non-genomic Pim-1/Bad-Pser75 module is required for an efficient pro-survival effect of Bcl-xL induced by androgen in LNCaP cells

Jaspal Kaur Kumar et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Naturally Secreted Amyloid-β Increases Mammalian Target of Rapamycin (mTOR) Activity via a PRAS40-mediated Mechanism

Antonella Caccamo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau EFFECTS ON COGNITIVE IMPAIRMENTS

Antonella Caccamo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Medicine, General & Internal

MECHANISMS OF DISEASE Alzheimer's Disease

Henry W. Querfurth et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Oncology

PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells

Fengxue Zhang et al.

CANCER BIOLOGY & THERAPY (2009)

Review Cell Biology

The ubiquitin-proteasome system in Alzheimer's disease

Salvatore Oddo

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)

Article Geriatrics & Gerontology

Aβ inhibits the proteasome and enhances amyloid and tau accumulation

Bertrand P. Tseng et al.

NEUROBIOLOGY OF AGING (2008)

Article Biochemistry & Molecular Biology

PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding

Lifu Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

Yasemin Sancak et al.

MOLECULAR CELL (2007)

Article Cell Biology

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

Emilie Vander Haar et al.

NATURE CELL BIOLOGY (2007)

Review Biochemistry & Molecular Biology

TOR signaling in growth and metabolism

S Wullschleger et al.

Review Biochemistry & Molecular Biology

TOR signaling in growth and metabolism

Stephan Wullschleger et al.

Article Biochemistry & Molecular Biology

Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002

MD Jacobs et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Alzheimer's disease:: Aβ, tau and synaptic dysfunction

FM LaFerla et al.

TRENDS IN MOLECULAR MEDICINE (2005)

Review Biochemistry & Molecular Biology

Methods for monitoring autophagy

N Mizushima

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Impaired proteasome function in Alzheimer's disease

JN Keller et al.

JOURNAL OF NEUROCHEMISTRY (2000)