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Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro
Chloe K. Nobuhara et al.
AMERICAN JOURNAL OF PATHOLOGY (2017)
Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model
Rebecca M. Nisbet et al.
BRAIN (2017)
Nociceptive neuronal Fc-gamma receptor I is involved in IgG immune complex induced pain in the rat
Haowu Jiang et al.
BRAIN BEHAVIOR AND IMMUNITY (2017)
Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer's Disease
Lisa Kirouac et al.
ENEURO (2017)
Internalization of tau antibody and pathological tau protein detected with a flow cytometry multiplexing approach
Dov B. Shamir et al.
ALZHEIMERS & DEMENTIA (2016)
FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease
Waltraud Mair et al.
ANALYTICAL CHEMISTRY (2016)
Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease
Rik Ossenkoppele et al.
BRAIN (2016)
Early and protective microglial activation in Alzheimer's disease: a prospective study using 18F-DPA-714 PET imaging
Lorraine Hamelin et al.
BRAIN (2016)
Potential mechanisms and implications for the formation of tau oligomeric strains
Julia E. Gerson et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)
Sweeping antibody as a novel therapeutic antibody modality capable of eliminating soluble antigens from circulation
Tomoyuki Igawa et al.
IMMUNOLOGICAL REVIEWS (2016)
Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer's Disease, Progressive Supranuclear Palsy, and Dementia with Lewy Bodies
Nicolas R. Barthelemy et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
A Phase IIa Randomized Control Trial of VEL015 ( Sodium Selenate) in Mild-Moderate Alzheimer's Disease
Charles B. Malpas et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets
Tengfei Li et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity
Nicolas R. Barthelemy et al.
JOURNAL OF PROTEOME RESEARCH (2016)
Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial
Serge Gauthier et al.
LANCET (2016)
CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis
Bob Olsson et al.
LANCET NEUROLOGY (2016)
Charge heterogeneity: Basic antibody charge variants with increased binding to Fc receptors
Beate Hintersteiner et al.
MABS (2016)
Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy
Erin E. Congdon et al.
MOLECULAR NEURODEGENERATION (2016)
Detecting tau in serum of transgenic animal models after tau immunotherapy treatment
Cristina d'Abramo et al.
NEUROBIOLOGY OF AGING (2016)
Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo
Sarah K. Kaufman et al.
NEURON (2016)
Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement
Seung-Hye Lee et al.
CELL REPORTS (2016)
Loss of Bin1 Promotes the Propagation of Tau Pathology
Sara Calafate et al.
CELL REPORTS (2016)
Lipid peroxidation causes endosomal antigen release for cross-presentation
Ilse Dingjan et al.
SCIENTIFIC REPORTS (2016)
Specific Knockdown of Endogenous Tau Protein by Peptide-Directed Ubiquitin-Proteasome Degradation
Ting-Ting Chu et al.
CELL CHEMICAL BIOLOGY (2016)
The Translocon Protein Sec61 Mediates Antigen Transport from Endosomes in the Cytosol for Cross-Presentation to CD8+ T Cells
Matthias Zehner et al.
IMMUNITY (2015)
Distinct Therapeutic Mechanisms of Tau Antibodies PROMOTING MICROGLIAL CLEARANCE VERSUS BLOCKING NEURONAL UPTAKE
Kristen E. Funk et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics
Amita Datta-Mannan et al.
MABS (2015)
Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy
Asami Kondo et al.
NATURE (2015)
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
Sang-Won Min et al.
NATURE MEDICINE (2015)
Human secreted tau increases amyloid-beta production
Jessica Bright et al.
NEUROBIOLOGY OF AGING (2015)
Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics
Angela Schoch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Posttranslational modifications of α-tubulin in alzheimer disease
Fan Zhang et al.
TRANSLATIONAL NEURODEGENERATION (2015)
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
Katja Hochgraefe et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy
Dana Wagshal et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2015)
Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice
Tomohiro Umeda et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2015)
The Role of Tau Oligomers in the Onset of Alzheimer's Disease Neuropathology
Maria del Carmen Cardenas-Aguayo et al.
ACS CHEMICAL NEUROSCIENCE (2014)
Ceria Nanoparticles Stabilized by Organic Surface Coatings Activate the Lysosome-Autophagy System and Enhance Autophagic Clearance
Wensi Song et al.
ACS NANO (2014)
Primary age-related tauopathy (PART): a common pathology associated with human aging
John F. Crary et al.
ACTA NEUROPATHOLOGICA (2014)
Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease
Ludovic Collin et al.
BRAIN (2014)
Structure and Mechanism of Action of Tau Aggregation Inhibitors
Katryna Cisek et al.
CURRENT ALZHEIMER RESEARCH (2014)
Estimation of polyclonal IgG4 hybrids in normal human serum
Elizabeth Young et al.
IMMUNOLOGY (2014)
Neuronal uptake of anti-Hu antibody, but not anti-Ri antibody, leads to cell death in brain slice cultures
John E. Greenlee et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Antibody-Derived In Vivo Imaging of Tau Pathology
Senthilkumar Krishnaswamy et al.
JOURNAL OF NEUROSCIENCE (2014)
Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles
Diana L. Castillo-Carranza et al.
JOURNAL OF NEUROSCIENCE (2014)
Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge
Bing Li et al.
MABS (2014)
Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
David W. Sanders et al.
NEURON (2014)
First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model
Eva Kontsekova et al.
ALZHEIMERS RESEARCH & THERAPY (2014)
Protein phosphatase 2A dysfunction in Alzheimer's disease
Jean-Marie Sontag et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Repeated immunization of mice with phosphorylated-tau peptides causes neuroinflammation
Lea Rozenstein-Tsalkovich et al.
EXPERIMENTAL NEUROLOGY (2013)
Curcumin Suppresses Soluble Tau Dimers and Corrects Molecular Chaperone, Synaptic, and Behavioral Deficits in Aged Human Tau Transgenic Mice
Qiu-Lan Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Antibody Uptake into Neurons Occurs Primarily via Clathrin-dependent Fcγ Receptor Endocytosis and Is a Prerequisite for Acute Tau Protein Clearance
Erin E. Congdon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Two Novel Tau Antibodies Targeting the 396/404 Region Are Primarily Taken Up by Neurons and Reduce Tau Protein Pathology
Jiaping Gu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The constant region affects antigen binding of antibodies to DNA by altering secondary structure
Yumin Xia et al.
MOLECULAR IMMUNOLOGY (2013)
Alzheimer disease therapy-moving from amyloid-β to tau
Ezio Giacobini et al.
NATURE REVIEWS NEUROLOGY (2013)
Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo
Kiran Yanamandra et al.
NEURON (2013)
Microtubule-stabilizing peptides and small molecules protecting axonal transport and brain function: Focus on davunetide (NAP)
Iddo Magen et al.
NEUROPEPTIDES (2013)
Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity
Cristina d'Abramo et al.
PLOS ONE (2013)
Brain homogenates from human tauopathies induce tau inclusions in mouse brain
Florence Clavaguera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
IgG Subclass and Heavy Chain Domains Contribute to Binding and Protection by mAbs to the Poly γ-D-glutamic Acid Capsular Antigen of Bacillus anthracis
Maria Hovenden et al.
PLOS PATHOGENS (2013)
The importance of tau phosphorylation for neurodegenerative diseases
Wendy Noble et al.
FRONTIERS IN NEUROLOGY (2013)
Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders
Sara Hall et al.
ARCHIVES OF NEUROLOGY (2012)
Interaction of Tau Protein with Model Lipid Membranes Induces Tau Structural Compaction and Membrane Disruption
Emmalee M. Jones et al.
BIOCHEMISTRY (2012)
Proline Isomer-Specific Antibodies Reveal the Early Pathogenic Tau Conformation in Alzheimer's Disease
Kazuhiro Nakamura et al.
CELL (2012)
The constant region contributes to the antigenic specificity and renal pathogenicity of murine anti-DNA antibodies
Yumin Xia et al.
JOURNAL OF AUTOIMMUNITY (2012)
Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
Peter T. Nelson et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2012)
TPI-287, a New Taxane Family Member, Reduces the Brain Metastatic Colonization of Breast Cancer Cells
Daniel P. Fitzgerald et al.
MOLECULAR CANCER THERAPEUTICS (2012)
The non-fluent/agrammatic variant of primary progressive aphasia
Murray Grossman
LANCET NEUROLOGY (2012)
Hyperphosphorylation and Cleavage at D421 Enhance Tau Secretion
Vanessa Plouffe et al.
PLOS ONE (2012)
Methylene Blue Reduced Abnormal Tau Accumulation in P301L Tau Transgenic Mice
Masato Hosokawa et al.
PLOS ONE (2012)
Isotype modulates epitope specificity, affinity, and antiviral activities of anti-HIV-1 human broadly neutralizing 2F5 antibody
Daniela Tudor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease
Alberto Serrano-Pozo et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Neuronal Fc-gamma receptor I mediated excitatory effects of IgG immune complex on rat dorsal root ganglion neurons
Lintao Qu et al.
BRAIN BEHAVIOR AND IMMUNITY (2011)
Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models REDUCTION OF TAU PATHOLOGY AND DELAY OF DISEASE PROGRESSION
Xiyun Chai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Sequence-independent Control of Peptide Conformation in Liposomal Vaccines for Targeting Protein Misfolding Diseases
David T. Hickman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
Allal Boutajangout et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Intraneuronal Amyloid β Oligomers Cause Cell Death Via Endoplasmic Reticulum Stress, Endosomal/Lysosomal Leakage, and Mitochondrial Dysfunction In Vivo
Tomohiro Umeda et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2011)
Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles
K. E. Funk et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2011)
Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease
Eliezer Masliah et al.
PLOS ONE (2011)
Biomarkers in frontotemporal lobar degenerations-Progress and challenges
William T. Hu et al.
PROGRESS IN NEUROBIOLOGY (2011)
Mechanistic Studies of Antibody-Mediated Clearance of Tau Aggregates Using an ex vivo Brain Slice Model
Pavan K. Krishnamurthy et al.
Frontiers in Psychiatry (2011)
Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
Ju-Hyun Lee et al.
CELL (2010)
Evidence for neuronal expression of functional Fc (epsilon and gamma) receptors
Hanneke van der Kleij et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)
LiCl Attenuates Thapsigargin-Induced Tau Hyperphosphorylation by Inhibiting GSK-3 beta In Vivo and In Vitro
Zheng-Qi Fu et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer's disease model
Niall M. Corcoran et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2010)
Purkinje Cell Death After Uptake of Anti-Yo Antibodies in Cerebellar Slice Cultures
John E. Greenlee et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2010)
Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model
Allal Boutajangout et al.
JOURNAL OF NEUROSCIENCE (2010)
Circular Dichroism reveals evidence of coupling between immunoglobulin constant and variable region secondary structure
Alena Janda et al.
MOLECULAR IMMUNOLOGY (2010)
Fcγ RECEPTORS CONTRIBUTE TO PYRAMIDAL CELL DEATH IN THE MOUSE HIPPOCAMPUS FOLLOWING LOCAL KAINIC ACID INJECTION
S. Suemitsu et al.
NEUROSCIENCE (2010)
Immunopositivity for ESCRT-III subunit CHMP2B in granulovacuolar degeneration of neurons in the Alzheimer's disease hippocampus
Yuu Yamazaki et al.
NEUROSCIENCE LETTERS (2010)
Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models
Janet van Eersel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis
R. Blake Pepinsky et al.
PROTEIN SCIENCE (2010)
Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease
Wendy Noble et al.
FASEB JOURNAL (2009)
Tau Phosphorylation by cdk5 and Fyn in Response to Amyloid Peptide A beta(25-35): Involvement of Lipid Rafts
Paula Hernandez et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Tau - an inhibitor of deacetylase HDAC6 function
Mar Perez et al.
JOURNAL OF NEUROCHEMISTRY (2009)
β-Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin
Qiu-Lan Ma et al.
JOURNAL OF NEUROSCIENCE (2009)
Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo
Aran F. Labrijn et al.
NATURE BIOTECHNOLOGY (2009)
Amyloid activates GSK-3β to aggravate neuronal tauopathy in bigenic mice
Dick Terwel et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Curcumin as Curecumin:: From kitchen to clinic
Ajay Goel et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Isothermal Titration Calorimetry Reveals Differential Binding Thermodynamics of Variable Region-identical Antibodies Differing in Constant Region for a Univalent Ligand
Tarun K. Dam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Cathepsin D expression is decreased in Alzheimer's disease fibroblasts
Lorena Urbanelli et al.
NEUROBIOLOGY OF AGING (2008)
Protective effects of NSAIDs on the development of Alzheimer disease
Steven C. Vlad et al.
NEUROLOGY (2008)
CSF biomarkers in frontotemporal lobar degeneration with known pathology
H. Bian et al.
NEUROLOGY (2008)
Exchanging Murine and Human Immunoglobulin Constant Chains Affects the Kinetics and Thermodynamics of Antigen Binding and Chimeric Antibody Autoreactivity
Marcela Torres et al.
PLOS ONE (2007)
Protein S-guanylation by the biological signal 8-nitroguanosine 3′,5′-cyclic monophosphate
Tomohiro Sawa et al.
NATURE CHEMICAL BIOLOGY (2007)
Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements
Ayodeji A. Asuni et al.
JOURNAL OF NEUROSCIENCE (2007)
CD3 and immunoglobulin G Fc receptor regulate cerebellar functions
Kazuhiro Nakamura et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
The immunoglobulin heavy chain constant region affects kinetic and thermodynamic parameters of antibody variable region interactions with antigen
Marcela Torres et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Increased level of active GSK-3β in Alzheimer's disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration
K. Leroy et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2007)
beta-amyloid peptide toxicity in organotypic hippocampal slice culture involves Akt/PKB, GSK-3 beta, and PTEN
Melissa Nassif et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
Mannose 6-phosphate receptor targeting and its applications in human diseases
M. Gary-Bobo et al.
CURRENT MEDICINAL CHEMISTRY (2007)
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
Heiko Braak et al.
ACTA NEUROPATHOLOGICA (2006)
Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein
Hanna Rosenmann et al.
ARCHIVES OF NEUROLOGY (2006)
Ultrastructural characteristics of tau filaments in tauopathies: Immuno-electron microscopic demonstration of tau filaments in tauopathies
Kunimasa Arima
NEUROPATHOLOGY (2006)
Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine
Muhammad Omar Chohan et al.
FEBS LETTERS (2006)
Effects of α-synuclein immunization in a mouse model of Parkinson's disease
E Masliah et al.
NEURON (2005)
Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease
M Grossman et al.
ANNALS OF NEUROLOGY (2005)
Variable-region-ldentical antibodies differing in isotype demonstrate differences in fine specificity and idiotype
M Torres et al.
JOURNAL OF IMMUNOLOGY (2005)
Meta-analysis of nonsteroidal antiinflammatory drug use and risk of dementia
AJM de Craen et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2005)
Expression of Fc epsilon receptor I on primary sensory neurons in mice
T Andoh et al.
NEUROREPORT (2004)
O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
F Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed α-synuclein
C Zhou et al.
MOLECULAR THERAPY (2004)
Direct action of immunoglobulin G on primary sensory neurons through Fc gamma receptor I
T Andoh et al.
FASEB JOURNAL (2004)
Insulin-like growth factor-II/mannose-6-phosphate receptor: Widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype
C Hawkes et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Mannose 6-phosphate receptors: New twists in the tale
P Ghosh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
EM Mandelkow et al.
NEUROBIOLOGY OF AGING (2003)
p35/Cdk5 pathway mediates soluble amyloid-β peptide-induced tau phosphorylation in vitro
T Town et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Isotype can affect the fine specificity of an antibody for a polysaccharide antigen
GR McLean et al.
JOURNAL OF IMMUNOLOGY (2002)
A survey of Cdk5 activator p35 and p25 levels in Alzheimer's disease brains
HC Tseng et al.
FEBS LETTERS (2002)
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
JC Augustinack et al.
ACTA NEUROPATHOLOGICA (2002)
Impaired proteasome function in Alzheimer's disease
JN Keller et al.
JOURNAL OF NEUROCHEMISTRY (2000)