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Viruses use RNA decoys to thwart CRISPR defences

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NATURE
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NATURE PORTFOLIO
DOI: 10.1038/d41586-023-03133-z

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Non-coding RNAs; Microbiology

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Bacteria and archaea use RNA-guided defences to destroy viruses, but the viruses can produce RNA mimics to counteract these defences.
Bacteria and archaea are microorganisms that often use RNA-guided defences called CRISPR to destroy the genomes of viruses that infect them. It now emerges that viruses make RNAs that act as mimics to divert such defences.

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