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Essential oils from Plumbago europaea L. aerial parts (leaves, flowers): GC-MS analyses and literature biological properties

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NATURAL PRODUCT RESEARCH
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TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2023.2265537

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Plumbago europaea L; GC-MS; plumbagin; phtalic acid esters; essential oils; biological activity

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Plumbago europaea L., a plant with medicinal value, has been widely used in folk medicine in Syria for treating skin diseases. This study determined the chemical composition of essential oils extracted from the aerial parts of P. europaea L. and identified several bioactive compounds.
Plumbago europaea L. belongs to the family Plumbaginaceae, which has many medicinal and nutritional applications. It is among the significant medicinal herbs used widely in folk medicine in Syria to treat skin diseases such as eczema and psoriasis. There are no previous studies of the aerial parts' essential oils of this plant. So, herein we report on determining the chemical composition of essential oils extracted from the aerial parts of P. europaea L., which were collected from a mountainous area in Latakia Province, Syria, by utilising the GC-MS technique. The major compounds identified in the flower's essential oils were: plumbagin (32.4%), hexadecanoic acid (13.79%), heneicosane (9.03%) and 2,6-di-tert-butyl-4-ethylphenol (8.40%). While in the leaves' essential oils were phytol (17.97%), dibutyl phthalate (15.45%), heneicosane (6.91%) and hexahydrofarnesyl acetone (6.72%). In addition, according to the published literature, most of the identified compounds have been reported to exhibit significant biological activities. [GRAPHICS] .

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