4.6 Article

The Content and Principle of the Rare Ginsenosides Produced from Gynostemma pentaphyllum after Heat Treatment

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Immunology

Ginsenoside Rg5 alleviates Ang II-induced cardiac inflammation and remodeling by inhibiting the JNK/AP-1 pathway

Tianxiang Yu et al.

Summary: This study evaluated the effects of ginsenoside Rg5 on Ang II-induced cardiac remodeling and heart failure. It was found that Rg5 inhibited cardiac inflammation, myocardial fibrosis, and hypertrophy, and prevented cardiac malfunction in mice challenged with Ang II, through the JNK/AP-1 signaling pathway.

INTERNATIONAL IMMUNOPHARMACOLOGY (2023)

Article Plant Sciences

Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway

Jingyu Ni et al.

Summary: This study confirms the protective effect of ginsenoside Rg3 on heart function in TAC-induced heart failure mice and reveals the molecular mechanisms involved in regulating glucose metabolism and improving insulin resistance.

JOURNAL OF GINSENG RESEARCH (2022)

Article Biochemistry & Molecular Biology

Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway

Haoping Lu et al.

Summary: Hepatocellular carcinoma (HCC), one of the deadliest cancers worldwide, can be effectively inhibited through the suppression of glutamine metabolism using ginsenoside Rk1. Rk1 not only inhibits HCC proliferation by inducing cell cycle arrest and apoptosis, but also regulates the ERK/c-Myc signaling pathway to suppress glutamine metabolism. This study suggests that Rk1 could be a promising candidate for clinical HCC treatment.

FOOD & FUNCTION (2022)

Article Plant Sciences

Stem-leaves of Panax as a rich and sustainable source of less-polar ginsenosides: comparison of ginsenosides from Panax ginseng, American ginseng and Panax notoginseng prepared by heating and acid treatment

Fengxiang Zhang et al.

Summary: The study found that Panax notoginseng had the highest content of ginsenosides, with polar ginsenosides decreasing and less-polar compounds increasing after transformation. The contents of saponins in the stem-leaves were higher than those in the roots. Notoginseng showed higher conversion rate and lower loss ratio.

JOURNAL OF GINSENG RESEARCH (2021)

Article Plant Sciences

Influence of the plant growth promoting Rhizobium panacihumi on aluminum resistance in Panax ginseng

Jong-Pyo Kang et al.

Summary: The study identified Rhizobium panacihumi DCY116(T) as a potential plant growth-promoting rhizobacteria for ginseng cultivation. Ginseng seedlings treated with this strain showed increased biomass, proline, total phenolic, and total soluble sugar contents, as well as elevated gene expressions compared to non-bacterized seedlings under aluminum stress.

JOURNAL OF GINSENG RESEARCH (2021)

Article Chemistry, Medicinal

Treatment for liver cancer: From sorafenib to natural products

Shuli Man et al.

Summary: This article discusses the formation process and therapeutic targets of liver cancer, as well as the current development of natural products in anti-liver cancer treatment. It points out the potential advantages of natural products in intervening in the formation and development of liver cancer.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)

Article Chemistry, Physical

Biocatalysis for Rare Ginsenoside Rh2 Production in High Level with Co-Immobilized UDP-Glycosyltransferase Bs-YjiC Mutant and Sucrose Synthase AtSuSy

Jianlin Chu et al.

Summary: The study established a green and sustainable method for the production of ginsenoside Rh2 at a high titer using a dual enzyme co-immobilization approach, which significantly improved enzyme binding stability and substrate concentration, leading to a high yield.

CATALYSTS (2021)

Article Plant Sciences

Ginsenoside Rg3 ameliorates allergic airway inflammation and oxidative stress in mice

Wen-Chung Huang et al.

Summary: The study showed that ginsenoside Rg3 significantly reduced airway inflammation, oxidative stress, and airway hyperresponsiveness in asthmatic mice, as well as decreased eosinophil infiltration. In tracheal epithelial cells, ginsenoside Rg3 also reduced inflammatory responses and oxidative stress.

JOURNAL OF GINSENG RESEARCH (2021)

Article Agriculture, Multidisciplinary

Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice

Yanyan Zhu et al.

Summary: The research discovered that Rg5 can enhance liver mitochondrial biogenesis and insulin sensitivity in db/db mice by activating specific signaling pathways, indicating its potential as a natural product for T2DM interventions.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Article Plant Sciences

Ginsenoside Rk1 suppresses platelet mediated thrombus formation by downregulation of granule release and αIIbβ3 activation

Jung-Hae Shin et al.

Summary: The study showed that G-Rk1 has an inhibitory effect on human platelet aggregation, particularly more effective on collagen-stimulated platelet aggregation. It can also suppress the activity of various platelet signaling molecules, thus blocking platelet formation of thrombosis.

JOURNAL OF GINSENG RESEARCH (2021)

Article Biochemistry & Molecular Biology

Changes of Ginsenoside Composition in the Creation of Black Ginseng Leaf

Wei Chen et al.

MOLECULES (2020)

Article Biotechnology & Applied Microbiology

Pulmonary Protective Functions of Rare Ginsenoside Rg4 on Particulate Matter-induced Inflammatory Responses

Wonhwa Lee et al.

BIOTECHNOLOGY AND BIOPROCESS ENGINEERING (2019)

Article Agriculture, Multidisciplinary

Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum)

Jun Wang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

Article Biochemistry & Molecular Biology

Generation of ginsenosides Rg3 and Rh2 from North American ginseng

DG Popovich et al.

PHYTOCHEMISTRY (2004)