期刊
MOLECULAR ECOLOGY
卷 26, 期 1, 页码 77-91出版社
WILEY
DOI: 10.1111/mec.13699
关键词
bilateral asymmetry; Perissodus microlepis; PoolSeq; quantitative trait; RADseq; scale-eating cichlid fish
资金
- International Max Planck Research School (IMPRS) for Organismal Biology
- DAAD [2015/16 57130104]
- Marie Curie IEF Fellowship [327875 - PlasticitySpeciation]
- German Research Foundation (DFG) [DFG15957314]
- University of Konstanz
- DFG [ME1725-18]
How polymorphisms consisting in left-right asymmetries are produced and maintained in natural populations is a tantalizing question, which remains largely unanswered. The scale-eating cichlid fish Perissodus microlepis is a remarkable example of extreme ecological specialization achieved by morphological and behavioural laterality. Its asymmetric mouth is accompanied by a pronounced lateralized foraging behaviour, where a left-bending morph preferentially feeds on the scales of the right side of its prey, while the opposite is true for the right morph. This striking asymmetry made this fish a textbook example of the astounding degree of ecological specialization and negative frequency-dependent selection. Yet, the genetic basis underlying this spectacular laterality remains unknown. We addressed this question through analyses of wild-caught fish using high-throughput DNA sequencing data. A novel array of SNP markers was developed by ddRAD sequencing (ddRADseq) and the use of pooled DNA samples (PoolSeq). We obtained more than 155 000 SNPs using ddRADseq and 3 900 000 SNPs with PoolSeq. Among these, we identified one (ddRAD) SNP, and 38 or 378 (PoolSeq) windows that are differentiated between the left and right morphs accounting for spurious associations due to geographic structuring. This allowed us to uncover candidate genomic regions that potentially contain genes for this trait. Then, this interesting trait has a genetic basis that is likely to be influenced by multiple loci. This result contributes to a greater understanding of the genetic bases of left-right asymmetry and, ultimately, the evolutionary processes governing the maintenance of this striking case of laterality.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据