Hydrogels for the Treatment of Myocardial Infarction: Design and Therapeutic Strategies

Cardiovascular diseases (CVDs) have become the leading global burden of diseases in recent years and are the primary cause of human mortality and loss of healthy life expectancy. Myocardial infarction (MI) is the top cause of CVDs-related deaths, and its incidence is increasing worldwide every year. Recently, hydrogels have garnered great interest from researchers as a promising therapeutic option for cardiac tissue repair after MI. This is due to their excellent properties, including biocompatibility, mechanical properties, injectable properties, anti-inflammatory properties, antioxidant properties, angiogenic properties, and conductive properties. This review discusses the advantages of hydrogels as a novel treatment for cardiac tissue repair after MI. The design strategies of various hydrogels in MI treatment are then summarized, and the latest research progress in the field is classified. Finally, the future perspectives of this booming field are also discussed at the end of this review. Myocardial infarction (MI) is the top cause of cardiovascular disease-related deaths. Hydrogels have garnered great interest from researchers as a promising therapeutic option for cardiac tissue repair after MI. This review discusses the design and therapeutic strategies of hydrogels as a novel treatment for cardiac tissue repair after MI.image

Automated summary

Cardiovascular diseases have become a major global burden, causing deaths and loss of healthy life expectancy. Myocardial infarction is the leading cause of cardiovascular disease-related deaths, and researchers have shown great interest in hydrogels as a potential therapy for cardiac tissue repair after myocardial infarction. This review summarizes the advantages of hydrogels as a novel treatment, discusses the design strategies and therapeutic strategies of different hydrogels, and provides an overview of the latest research progress and future perspectives in this field.