Bioderived Mesoporous Carbon@Tungsten Oxide Nanocomposite as a Drug Carrier Vehicle of Doxorubicin for Potent Cancer Therapy

Scientistshave investigated the possibility of employing nanomaterialsas drug carriers. These nanomaterials can preserve their content andtransport it to the target region in the body. In this investigation,we proposed a simple method for developing distinctive, bioderivednanostructures with mesoporous carbon nanoparticles impregnated withtungsten oxide (WO3). Prior to characterizing and encapsulatingWO(3) with bioderived mesoporous carbon, the anticancer drugdoxorubicin (DOX) was added to the nanoparticles and examined loadingand release study. The approaches for both nanoparticle productionand characterization are discussed in detail. Colloidal qualitiesof the nanomaterial can be effectively preserved while also allowingtransdermal transportation of nanoparticles into the body by formingthem into green, reusable, and porous nanostructures. Although thetheories of nanoparticles and bioderived carbon each have been studiedseparately, the combination presents a new route to applications connectedto nanomedicine. Furthermore, this sample was used to study exoticbiomedical applications, such as antioxidant, antimicrobial, and anticanceractivities. The W-3 sample had lower antioxidant activity (44.01%)than the C@W sample (56.34%), which was the most potent. A high DOXentrapment effectiveness of 97% was eventually achieved by the C@Wsample, compared to a pure WO3 entrapment efficiency of91%. It was observed that the Carbon/WO3 composite (C@W)sample showed more efficacy because the mesoporous carbon compositionwith WO3 increases the average surface area and surface-activelocations.

Automated summary

Scientists investigated the use of nanomaterials as drug carriers, developing a method to create bioderived nanostructures with mesoporous carbon nanoparticles and tungsten oxide (WO3). The nanoparticles were loaded with the anticancer drug doxorubicin (DOX), and their production and characterization processes were discussed. The combination of nanoparticles and bioderived carbon offers a new route for nanomedicine applications. The Carbon/WO3 composite (C@W) showed higher effectiveness due to increased surface area and active locations.