4.8 Editorial Material

Interventions to prevent dementia should target those at high risk

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Article Public, Environmental & Occupational Health

Effects of eligibility criteria on patient selection and treatment implications from 10 multidomain dementia prevention trials: a population-based study

Silvan Licher et al.

Summary: Multidomain dementia prevention trials fail to prioritize high-risk dementia patients, and mostly include individuals who already meet cardiovascular prevention guidelines. Better targeting of recruitment for individuals whose trial results can improve clinical decision making is needed.

NEUROEPIDEMIOLOGY (2023)

Review Clinical Neurology

Association of Hearing Aids and Cochlear Implants With Cognitive Decline and Dementia A Systematic Review and Meta-analysis

Brian Sheng Yep Yeo et al.

Summary: Hearing loss is linked to cognitive decline, but the effect of hearing restorative devices on cognition is unclear. This study evaluated the associations between hearing aids and cochlear implants with cognitive decline and dementia. The findings suggest that the use of hearing restorative devices is associated with a 19% decrease in the risk of long-term cognitive decline and a 3% improvement in short-term cognitive test scores.

JAMA NEUROLOGY (2023)

Editorial Material Public, Environmental & Occupational Health

Preventing dementiathrough correcting hearing: huge progress but more to do

Gill Livingston et al.

LANCET PUBLIC HEALTH (2023)

Article Public, Environmental & Occupational Health

Association between hearing aid use and all-cause and cause-specific dementia: an analysis of the UK Biobank cohort

Fan Jiang et al.

Summary: The use of hearing aids is associated with a similar risk of dementia in people with hearing loss as compared to those without. Hearing loss accounts for 29.6% of the attributable risk of dementia, and the association between hearing aid use and dementia is partially mediated by reducing social isolation, loneliness, and depressed mood.

LANCET PUBLIC HEALTH (2023)

Article Medicine, General & Internal

Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial

Frank R. Lin et al.

Summary: This study aimed to investigate the impact of a hearing intervention on cognitive decline in older adults. The results showed that the hearing intervention did not reduce cognitive decline over 3 years in the total sample. However, a sensitivity analysis indicated that the hearing intervention might reduce cognitive change in populations at increased risk for cognitive decline.

LANCET (2023)

Article Cell Biology

Social participation and risk of developing dementia

Andrew Sommerlad et al.

Summary: The increasing number of people with dementia globally highlights the urgent need to reduce its scale and impact. Lifetime social participation may play a crucial role in reducing dementia risk and could have implications for individual behavior and public health policy. However, more research is needed to fully understand the causal relationship.

NATURE AGING (2023)

Article Sport Sciences

Effects of 5 Years Aerobic Exercise on Cognition in Older Adults: The Generation 100 Study: A Randomized Controlled Trialy

Ekaterina Zotcheva et al.

Summary: The study aimed to investigate the association between a 5-year exercise intervention and change in peak oxygen uptake with cognitive function in older adults. Overall, exercise was not significantly associated with cognition among older adults. However, maintaining or increasing VO2peak appeared to benefit cognition.

SPORTS MEDICINE (2022)

Review Medicine, General & Internal

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

Gill Livingston et al.

LANCET (2020)

Review Medicine, General & Internal

Dementia prevention, intervention, and care

Gill Livingston et al.

LANCET (2017)