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Review
Microbiology
Hannah E. Davis et al.
Summary: Long COVID is a common and debilitating illness that affects at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, with a wide range of symptoms and impacts on multiple organ systems. There are an estimated 65 million individuals worldwide with long COVID, and the number of cases is increasing daily. Current diagnostic and treatment options are insufficient, and there is a need for clinical trials to address leading hypotheses. Future research should account for biases and testing issues, build on viral-onset research, include marginalized populations, and meaningfully engage patients.
NATURE REVIEWS MICROBIOLOGY
(2023)
Article
Infectious Diseases
Waasila Jassat et al.
Summary: The study aimed to describe the prevalence of and risk factors for post-COVID-19 condition (PCC). A total of 46.7% of hospitalized and 18.5% of nonhospitalized participants experienced >= 1 symptoms at 6 months. Risk factors for PCC included older age, female sex, non-Black race, presence of a comorbidity, greater number of acute COVID-19 symptoms, hospitalization/COVID-19 severity, and wave period.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Review
Infectious Diseases
Joan B. Soriano et al.
Summary: People with COVID-19 might experience long-term symptoms known as long COVID or long-haul COVID. The lack of a standardized definition hinders the understanding and treatment of this condition. In a WHO-led Delphi process, a consensus definition was developed, stating that post-COVID-19 condition occurs in individuals with a history of SARS-CoV-2 infection, with symptoms lasting for at least 2 months and impacting everyday functioning. This common framework provides a foundation for future studies and therapy.
LANCET INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Ann Danaiya Usher
Editorial Material
Medicine, General & Internal
Evelyne de Leeuw et al.
Summary: This statement implies that the pandemic will persist, and emphasizes the importance of addressing the inequities it has caused.
MEDICAL JOURNAL OF AUSTRALIA
(2022)
Review
Infectious Diseases
Felicia Ceban et al.
Summary: This scoping review explores ongoing clinical trials testing candidate treatments for long COVID, indicating a need for stricter and more consistent characterization and inclusion/exclusion criteria. The majority of proposed interventions are non-pharmacological, targeting multiple long COVID symptoms or respiratory/pulmonary sequelae.
INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Debbie Bradshaw et al.
Lancet Global Health
(2022)
Article
Medicine, General & Internal
Louise Sigfrid et al.
Summary: Very little is currently known about the possible clinical sequelae that may persist after resolution of acute COVID-19. A recent longitudinal cohort study from Italy reported that 87% of patients had at least one ongoing symptom at 60-day follow-up after hospitalisation with COVID-19, suggesting that COVID-19 patients may require more psychological support than typical ICU patients. This study aims to characterize physical and psychosocial sequelae in patients post-COVID-19 hospital discharge and provide insights for long-term consequences prevention and clinical management.
Editorial Material
Medicine, General & Internal
Manoj Sivan et al.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Review
Public, Environmental & Occupational Health
Melina Michelen et al.
Summary: Long COVID is a complex condition with prolonged and heterogeneous symptoms, including weakness, general malaise, fatigue, concentration impairment, and breathlessness. Approximately 37% of patients reported reduced quality of life, and 26% of studies presented evidence of reduced pulmonary function. There is an urgent need for further studies to explore the etiology, risk factors, and biomarkers of long COVID in different populations and settings.