相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic Amines
Cheyenne Chaplain et al.
ACS MEDICINAL CHEMISTRY LETTERS (2023)
Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity
Annemarie Laumaea et al.
CELL REPORTS (2023)
HIV-1 remission and possible cure in a woman after haplo-cord blood transplant
Jingmei Hsu et al.
CELL (2023)
Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity
Christopher J. Fritschi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2023)
Temsavir Modulates HIV-1 Envelope Conformation by Decreasing Its Proteolytic Cleavage
Marianne Boutin et al.
VIRUSES-BASEL (2023)
Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC
Shilei Ding et al.
VIRUSES-BASEL (2023)
Identification of Anti-gp41 Monoclonal Antibodies That Effectively Target Cytotoxic Immunoconjugates to Cells Infected with Human Immunodeficiency Virus, Type 1
Grant Klug et al.
VACCINES (2023)
Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120
Jonathan Richard et al.
CELL CHEMICAL BIOLOGY (2023)
Antibody-drug conjugates: in search of partners of choice
Jesus Fuentes-Antras et al.
TRENDS IN CANCER (2023)
In Vivo Dynamics of the Latent Reservoir for HIV-1: New Insights and Implications for Cure
Janet D. Siliciano et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2022)
HIV envelope antibodies and TLR7 agonist partially prevent viral rebound in chronically SHIV-infected monkeys
Brian Moldt et al.
PLoS Pathogens (2022)
Insights Into Persistent HIV-1 Infection and Functional Cure: Novel Capabilities and Strategies
Tram M. Ta et al.
FRONTIERS IN MICROBIOLOGY (2022)
TLR7 agonist, N6-LS and PGT121 delayed viral rebound in SHIV-infected macaques after antiretroviral therapy interruption
Denise C. Hsu et al.
PLOS PATHOGENS (2021)
Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics
Christopher J. Fritschi et al.
ACS MEDICINAL CHEMISTRY LETTERS (2021)
SMAC Mimetics as Therapeutic Agents in HIV Infection
Bengisu Molyer et al.
FRONTIERS IN IMMUNOLOGY (2021)
Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation
Claudia A. Jette et al.
NATURE COMMUNICATIONS (2021)
Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir
Jyothi K. Rajashekar et al.
CELL HOST & MICROBE (2021)
New Latency Reversing Agents for HIV-1 Cure: Insights from Nonhuman Primate Models
Katherine M. Bricker et al.
VIRUSES-BASEL (2021)
Bispecific Anti-HIV Immunoadhesins That Bind Gp120 and Gp41 Have Broad and Potent HIV-Neutralizing Activity
Seth H. Pincus et al.
VACCINES (2021)
Curing HIV: Seeking to Target and Clear Persistent Infection
David M. Margolis et al.
CELL (2020)
Broadly neutralizing antibodies combined with latency-reversing agents or immune modulators as strategy for HIV-1 remission
Jesper Damsgaard Gunst et al.
CURRENT OPINION IN HIV AND AIDS (2020)
SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIVCCH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques
Amir Dashti et al.
JOURNAL OF VIROLOGY (2020)
Opening the HIV envelope: potential of CD4 mimics as multifunctional HIV entry inhibitors
Annemarie Laumaea et al.
CURRENT OPINION IN HIV AND AIDS (2020)
Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation
Katherine M. Bricker et al.
PLOS PATHOGENS (2020)
A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity
Shilei Ding et al.
JOURNAL OF VIROLOGY (2019)
Development of an Effective Scalable Enantioselective Synthesis of the HIV-1 Entry Inhibitor BNM-III-170 as the Bis-trifluoroacetate Salt
Junhua Chen et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2019)
Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir
Nicholas A. Meanwell et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
eCD4-Ig Variants That More Potently Neutralize HIV-1
Ina Fetzer et al.
JOURNAL OF VIROLOGY (2018)
Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys (vol 563, pg 360, 2018)
Erica N. Borducchi et al.
NATURE (2018)
Design and In Vivo Characterization of Immunoconjugates Targeting HIV gp160
Seth H. Pincus et al.
JOURNAL OF VIROLOGY (2017)
Identification of Human Anti-HIV gp160 Monoclonal Antibodies That Make Effective Immunotoxins
Seth H. Pincus et al.
JOURNAL OF VIROLOGY (2017)
Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4+ T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity
Jonathan Richard et al.
EBIOMEDICINE (2016)
CD4 mimetics sensitize HIV-1-infected cells to ADCC
Jonathan Richard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Effect of the cytoplasmic domain on antigenic characteristics of HIV-1 envelope glycoprotein
Jia Chen et al.
SCIENCE (2015)
Exceptionally Potent and Broadly Cross-Reactive, Bispecific Multivalent HIV-1 Inhibitors Based on Single Human CD4 and Antibody Domains
Weizao Chen et al.
JOURNAL OF VIROLOGY (2014)
Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy
Julian H. Elliott et al.
PLOS PATHOGENS (2014)
Targeted Cytotoxic Therapy Kills Persisting HIV Infected Cells During ART
Paul W. Denton et al.
PLOS PATHOGENS (2014)
Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing
Datsen George Wei et al.
PLOS PATHOGENS (2014)
Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer
Jean-Philippe Julien et al.
SCIENCE (2013)
Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
Dmitry Lyumkis et al.
SCIENCE (2013)
Pre-Clinical Evaluation of a 213Bi-Labeled 2556 Antibody to HIV-1 gp41 Glycoprotein in HIV-1 Mouse Models as a Reagent for HIV Eradication
Ekaterina Dadachova et al.
PLOS ONE (2012)
Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation
Kristina Allers et al.
BLOOD (2011)
An HIV-1 gp120 Envelope Human Monoclonal Antibody That Recognizes a C1 Conformational Epitope Mediates Potent Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity and Defines a Common ADCC Epitope in Human HIV-1 Serum
Guido Ferrari et al.
JOURNAL OF VIROLOGY (2011)
Broad neutralization coverage of HIV by multiple highly potent antibodies
Laura M. Walker et al.
NATURE (2011)
Immunotoxin Complementation of HAART to Deplete Persisting HIV-Infected Cell Reservoirs
Edward A. Berger et al.
PLOS PATHOGENS (2010)
Targeted killing of virally infected cells by radiolabeled antibodies to viral proteins
Ekaterina Dadachova et al.
PLOS MEDICINE (2006)
Molecular characterization, reactivation, and depletion of latent HIV
DG Brooks et al.
IMMUNITY (2003)
In vivo efficacy of anti-glycoprotein 41, but not anti-glycoprotein 120, immunotoxins in a mouse model of HIV infection
SH Pincus et al.
JOURNAL OF IMMUNOLOGY (2003)
Increased affinity and stability of an anti-HIV-1 envelope immunotoxin by structure-based mutagenesis
L McHugh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Recombinant CD4-IgG2 in human immunodeficiency virus type 1-infected children: Phase 1/2 study
WT Shearer et al.
JOURNAL OF INFECTIOUS DISEASES (2000)
Chimeric toxins targeted to the human immunodeficiency virus type 1 envelope glycoprotein augment the in vivo activity of combination antiretroviral therapy in thy/liv-SCID-Hu mice
H Goldstein et al.
JOURNAL OF INFECTIOUS DISEASES (2000)