相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cancer Statistics, 2016
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2016)
Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity
Gagan Deep et al.
SCIENTIFIC REPORTS (2016)
Hypoxia and Prostate Cancer Aggressiveness: A Tale With Many Endings
Avelino Fraga et al.
CLINICAL GENITOURINARY CANCER (2015)
Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[18F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts
Isabel R. Schlaepfer et al.
MOLECULAR IMAGING AND BIOLOGY (2015)
HIF-1 alpha Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase
Jayasri Nanduri et al.
PLOS ONE (2015)
Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation
Isabel R. Schlaepfer et al.
ONCOTARGET (2015)
The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer
H. B. Ragnum et al.
BRITISH JOURNAL OF CANCER (2015)
Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules
Anand Ramteke et al.
MOLECULAR CARCINOGENESIS (2015)
Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia
Rakesh K. Jain
CANCER CELL (2014)
ADC mapping and T1-weighted signal changes on post-injury MRI predict seizure susceptibility after experimental traumatic brain injury
Lauren Frey et al.
NEUROLOGICAL RESEARCH (2014)
Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1
Dhanya K. Nambiar et al.
ONCOTARGET (2014)
The effects of nonspecific HIF1α inhibitors on development of castrate resistance and metastases in prostate cancer
Weranja K. B. Ranasinghe et al.
CANCER MEDICINE (2014)
The fat side of prostate cancer
Giorgia Zadra et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)
Inositol Hexaphosphate Inhibits Tumor Growth, Vascularity, and Metabolism in TRAMP Mice: A Multiparametric Magnetic Resonance Study
Komal Raina et al.
CANCER PREVENTION RESEARCH (2013)
The Role of Hypoxia-Inducible Factor 1α in Determining the Properties of Castrate-Resistant Prostate Cancers
Weranja K. B. Ranasinghe et al.
PLOS ONE (2013)
Tumor Hypoxia Predicts Biochemical Failure following Radiotherapy for Clinically Localized Prostate Cancer
Michael Milosevic et al.
CLINICAL CANCER RESEARCH (2012)
Angiopreventive Efficacy of Pure Flavonolignans from Milk Thistle Extract against Prostate Cancer: Targeting VEGF-VEGFR Signaling
Gagan Deep et al.
PLOS ONE (2012)
Anti-Cancer Drugs Targeting Fatty Acid Synthase (FAS)
Puspa R. Pandey et al.
Recent Patents on Anti-Cancer Drug Discovery (2012)
Lipids and prostate cancer
Janel Suburu et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2012)
Role of E-cadherin in Antimigratory and Antiinvasive Efficacy of Silibinin in Prostate Cancer Cells
Gagan Deep et al.
CANCER PREVENTION RESEARCH (2011)
Hypoxia-Inducible Factor 1 Mediates Increased Expression of NADPH Oxidase-2 in Response to Intermittent Hypoxia
Guoxiang Yuan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2011)
Metabolic alterations and targeted therapies in prostate cancer
Richard Flavin et al.
JOURNAL OF PATHOLOGY (2011)
Hypoxia enhances transcriptional activity of androgen receptor through hypoxia-inducible factor-1 alpha in a low androgen environment
Takakazu Mitani et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2011)
Diffusion MR Imaging for Monitoring of Treatment Response
Anwar R. Padhani et al.
MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA (2011)
A Novel Two-Stage, Transdisciplinary Study Identifies Digoxin as a Possible Drug for Prostate Cancer Treatment
Elizabeth A. Platz et al.
CANCER DISCOVERY (2011)
The relevance of a hypoxic tumour microenvironment in prostate cancer
Grant D. Stewart et al.
BJU INTERNATIONAL (2010)
Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer
Gagan Deep et al.
CANCER AND METASTASIS REVIEWS (2010)
De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
Evelien Rysman et al.
CANCER RESEARCH (2010)
Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis
Xin Lu et al.
CLINICAL CANCER RESEARCH (2010)
The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1
Isabel Diebold et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment
Eui Jung Moon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Silibinin inhibits expression of HIF-1α through suppression of protein translation in prostate cancer cells
Hui-Jung Jung et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Silibinin Suppresses Growth of Human Prostate Carcinoma PC-3 Orthotopic Xenograft via Activation of Extracellular Signal-Regulated Kinase 1/2 and Inhibition of Signal Transducers and Activators of Transcription Signaling
Rana R. Singh et al.
CLINICAL CANCER RESEARCH (2009)
Silibinin inhibits hypoxia-inducible factor-1α and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy
P. Garcia-Maceira et al.
ONCOGENE (2009)
Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model
Komal Raina et al.
CANCER RESEARCH (2008)
Silibinin Inhibits Established Prostate Tumor Growth, Progression, Invasion, and Metastasis and Suppresses Tumor Angiogenesis and Epithelial-Mesenchymal Transition in Transgenic Adenocarcinoma of the Mouse Prostate Model Mice
Rana P. Singh et al.
CLINICAL CANCER RESEARCH (2008)
Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study
Roy Vergis et al.
LANCET ONCOLOGY (2008)
Hypoxia: A key regulator of angiogenesis in cancer
Debbie Liao et al.
CANCER AND METASTASIS REVIEWS (2007)
NAD(P)H Oxidases regulate HIF-2α protein expression
Karen Block et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Androgen-insensitive prostate cancer cells transiently respond to castration treatment when growing in an androgen-dependent prostate environment
Sofia Halin et al.
PROSTATE (2007)
A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients
Thomas W. Flaig et al.
INVESTIGATIONAL NEW DRUGS (2007)
Pilot study of oral silibinin, a putative chemopreventive agent, in colorectal cancer patients: Silibinin levels in plasma, colorectum, and liver and their pharmacodynamic consequences
C Hoh et al.
CLINICAL CANCER RESEARCH (2006)
Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin
G Deep et al.
ONCOGENE (2006)
Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-κB:: implications for angioprevention and antiangiogenic therapy
RP Singh et al.
ONCOGENE (2005)
Up-regulation of hypoxia-inducible factor 1 alpha is an early event in prostate carcinogenesis
H Zhong et al.
CANCER DETECTION AND PREVENTION (2004)
Hypoxia - A key regulatory factor in tumour growth
AL Harris
NATURE REVIEWS CANCER (2002)