期刊
JOURNAL OF ULTRASOUND IN MEDICINE
卷 -, 期 -, 页码 -出版社
WILEY
DOI: 10.1002/jum.16341
关键词
adverse events; children; contrast-enhanced ultrasound; sickle cell disease; sickle cell trait; ultrasound contrast agents
There has been an increase in pain-related adverse events with the use of UCA Definity in adults. No studies have investigated the incidence of similar adverse events with UCA Lumason or Optison yet. Our experience suggests that the use of Lumason and Optison for contrast-enhanced ultrasound exams in children with sickle cell disease is safe.
Ultrasound contrast agent (UCA) use is increasing. Recent isolated reports observed a rise in pain-related adverse events with the intravenous administration of the UCA Definity in adults with sickle cell disease. To date, no studies have investigated the incidence of similar adverse events with UCA Lumason or Optison. We describe our experience regarding the safety of Lumason and Optison in children with sickle cell disease and trait who underwent contrast-enhanced ultrasound exams in our department with intravenous, intravesical, and other intracavitary routes. No pain-related or other adverse events were observed in this pediatric population with any route of UCA administration.
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