Thin polysaccharide films as carriers for local anesthetic drugs

Article Pharmacology & Pharmacy

Comparative Preclinical Study of Lidocaine and Mepivacaine in Resilient Hyaluronic Acid Fillers

Romain Brusini et al.

Summary: This study compared the influence of lidocaine and mepivacaine on fillers and found that they had similar effects, making both suitable as anesthetics for soft-tissue fillers.

PHARMACEUTICS (2022)

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Article Polymer Science

Preliminary Study of κ-Carrageenan Based Membranes for Anti-Inflammatory Drug Delivery

Dorinel Okolisan et al.

Summary: This study proposes a simple and effective method to obtain ultra-thin membranes based on kappa-carrageenan. By introducing various drugs, successful incorporation of active substances was achieved, and the membranes showed high thermal stability. The findings indicate that these membranes can be used for transdermal administration of anti-inflammatory substances.

POLYMERS (2022)

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Review Nutrition & Dietetics

Recent advances in carrageenan-based films for food packaging applications

Cheng Cheng et al.

Summary: Carrageenan-based films have gained attention in food packaging applications due to their low cost, biodegradability, compatibility, and film-forming property. This article provides a comprehensive review of recent developments in carrageenan-based films, including fabrication strategies, physical and chemical properties, and novel food packaging applications. The films can be enhanced by incorporating other compounds, making them suitable for extending the shelf life of food and monitoring freshness.

FRONTIERS IN NUTRITION (2022)

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Review Food Science & Technology

Sulfated polysaccharides and its commercial applications in food industries-A review

Janani Muthukumar et al.

Summary: This article explores the potential value of polysaccharides from marine seaweeds in food applications, focusing on their types and biological properties.

JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE (2021)

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Review Dentistry, Oral Surgery & Medicine

Tramadol as a local anaesthetic agent in dentistry: A systematic review of local and systemic adverse effects

Robert Jonathon Mane et al.

Summary: Tramadol is an effective local anaesthetic in dentistry with a low prevalence of adverse effects. Nausea and dizziness were the most commonly reported adverse effects, and the use of tramadol as a sole local anaesthetic showed lower incidence of adverse effects compared to when used as an adjunct.

SAUDI DENTAL JOURNAL (2021)

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Review Engineering, Environmental

Polysaccharides; Classification, Chemical Properties, and Future Perspective Applications in Fields of Pharmacology and Biological Medicine (A Review of Current Applications and Upcoming Potentialities)

Aiman Saleh A. Mohammed et al.

Summary: Polysaccharides, essential macromolecules with important biological functions, have drawn increasing attention due to their wide range of biological and pharmacological activities. They can be obtained from various sources and modified to enhance their properties, making them promising candidates in biomedical and pharmaceutical fields. Challenges and limitations in their pharmaceutical utilities are also discussed.

JOURNAL OF POLYMERS AND THE ENVIRONMENT (2021)

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Review Chemistry, Multidisciplinary

Polysaccharide Chemistry in Drug Delivery, Endocrinology, and Vaccines

Aimen Khalid et al.

Summary: The article highlights the importance of polysaccharides in drug delivery, particularly in the advantages of the transdermal route and the applications of various polysaccharides in the synthesis of membranes/films. It discusses the functionalization of polysaccharides and the prospects in therapeutic agent delivery.

CHEMISTRY-A EUROPEAN JOURNAL (2021)

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Article Chemistry, Physical

Current-status and applications of polysaccharides in drug delivery systems

Parteek Prasher et al.

Summary: Polysaccharide-based advanced drug delivery systems are biocompatible, able to encapsulate and control release of drug molecules, evade drug resistance, maintain optimal drug concentration at target sites, and minimize side effects. These systems have revolutionized tissue engineering, multi drug delivery, and cell culturing technologies.

COLLOID AND INTERFACE SCIENCE COMMUNICATIONS (2021)

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Article Food Science & Technology

Improved extraction of carrageenan from red seaweed (Chondracantus canaliculatus) using ultrasound-assisted methods and evaluation of the yield, physicochemical properties and functional groups

Angelina Martin-del-Campo et al.

Summary: The red seaweed Chondracanthus canaliculatus is an underexploited algae species that can be used as a potential source for obtaining carrageenan. Treatment of seaweed under alkaline conditions using ultrasound alone or combined with heat significantly increases the yield extraction and improves color and properties of carrageenan, making it more similar to commercial standards.

FOOD SCIENCE AND BIOTECHNOLOGY (2021)

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Review Medicine, General & Internal

Lidocaine: A Local Anesthetic, Its Adverse Effects and Management

Entaz Bahar et al.

Summary: Local anesthetics, especially lidocaine, are commonly used in dentistry with low risk of adverse allergic responses, but the reactions can range from moderate to life-threatening, requiring prompt diagnosis and treatment. This article reviews information on local anesthetics, their adverse reactions, causes, and management.

MEDICINA-LITHUANIA (2021)

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Review Plant Sciences