期刊
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
卷 -, 期 -, 页码 -出版社
WILEY
DOI: 10.1111/jgs.18568
关键词
dementia care; embedded pragmatic controlled trials; health equity; nonpharmacological interventions; underrepresented groups
Inequities in brain health, economic costs, and evidence base for dementia care persist. Achieving health equity in dementia care involves ensuring affected populations' full participation in and benefit from clinical research. Embedding proven interventions in real-world conditions and healthcare systems can enhance dementia care, resource utilization, and exam effectiveness. Developing ePCT research designs for non-pharmacological dementia care interventions requires careful considerations and frameworks for health equity readiness.
Inequities with regard to brain health, economic costs, and the evidence base for dementia care continue. Achieving health equity in dementia care requires rigorous efforts that ensure disproportionately affected populations participate fully in-and benefit from-clinical research. Embedding-proven interventions under real-world conditions and within existing healthcare systems have the potential to examine the effectiveness of an intervention, improve dementia care, and leverage the use of existing resources. Developing embedded pragmatic controlled trials (ePCT) research designs for nonpharmacological dementia care interventions involves a plethora of a priori assumptions and decisions. Although frameworks exist to determine whether interventions are ready for ePCT, there is no heuristic to assess health equity-readiness. We discuss health equity considerations, case examples, and research strategies across ePCT study domains of evidence, risk, and alignment. Future discussions regarding health equity considerations across other domains are needed.
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