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Kenji Kawai et al.
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George M. Burslem et al.
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Chao Zhang et al.
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Woondong Jeong et al.
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Brooke Bullock Lao et al.
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Haiquan Lu et al.
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Weirong Fang et al.
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Swati Kushal et al.
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Laura K. Henchey et al.
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M. Christiane Brahimi-Horn et al.
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Hyunju Cho et al.
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Shalini Patiar et al.
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Sheran H. W. Law et al.
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JHW Distler et al.
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JT Ernst et al.
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SA Dames et al.
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SJ Freedman et al.
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BP Orner et al.
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AL Kung et al.
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