☆ 4.5 Article

Proton Release Reactions in the Inward H+ Pump NsXeR

JOURNAL OF PHYSICAL CHEMISTRY B (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemistry & Molecular Biology

Mechanisms of inward transmembrane proton translocation

Kirill Kovalev et al.

Summary: By studying a bacterial inward proton-pumping rhodopsin, researchers have uncovered its molecular mechanism and revealed how proton wires mediate ion selectivity and proton transport through cell membrane. Proton transport is essential for cell life and understanding the mechanisms behind it is a challenge. The study presents a comprehensive function-structure analysis of a light-driven bacterial inward proton pump, providing insights into proton translocation and the use of synchrotron source for rhodopsin studies. The results also have implications for optogenetics.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Light-driven proton transfers and proton transport by microbial rhodopsins-A biophysical perspective

Leonid S. Brown

Summary: In the past twenty years, there have been significant breakthroughs in understanding the rules and mechanisms of proton transport in microbial rhodopsins, transitioning from atomic-level understanding to a confounding variety of new homologs. This review summarizes and discusses experimental data obtained on new microbial rhodopsin variants, with a focus on the vectoriality of proton transport and their structural determinants.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2022)

添加到收藏夹

Article Chemistry, Physical

Protein conformational changes and protonation dynamics probed by a single shot using quantum-cascade-laser-based IR spectroscopy

Luiz Schubert et al.

Summary: Mid-IR spectroscopy is used to investigate protein reactions. In this study, quantum-cascade-laser-based dual-comb spectroscopy is used to probe protein conformational changes and protonation events by a single-shot experiment. The feasibility of QCL-based infrared spectroscopy in monitoring irreversible reactions is demonstrated.

JOURNAL OF CHEMICAL PHYSICS (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

The Photoreaction of the Proton-Pumping Rhodopsin 1 From the Maize Pathogenic Basidiomycete Ustilago maydis

Mariafrancesca La Greca et al.

Summary: This study reports the spectroscopic characterization of a light-driven proton pump rhodopsin (UmRh1) from the smut pathogen Ustilago maydis. The impact of the auxin hormone indole-3-acetic acid on UmRh1 pump activity was also investigated. An easy pumping activity test was established to probe the ability of UmRh1 to pump protons out of living yeast cells.

FRONTIERS IN MOLECULAR BIOSCIENCES (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Membrane Protein Activity Induces Specific Molecular Changes in Nanodiscs Monitored by FTIR Difference Spectroscopy

Federico Baserga et al.

Summary: This study investigates the interaction between membrane proteins and the lipid bilayer by analyzing changes in lipid vibrational bands. The results show that the activation of membrane proteins leads to structural changes and perturbs the lipidic environment. Isotopologue analysis also reveals changes in the collective state of lipids.

FRONTIERS IN MOLECULAR BIOSCIENCES (2022)

添加到收藏夹

Article Chemistry, Physical

Contact-Mediated Retinal-Opsin Coupling Enables Proton Pumping in Gloeobacter Rhodopsin

Tomomi Shionoya et al.

Summary: Nonbonded atomic contacts between the chromophore and protein moiety play an essential role in driving functionally important structural changes following photoisomerization.

JOURNAL OF PHYSICAL CHEMISTRY B (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

The Voltage Dependent Sidedness of the Reprotonation of the Retinal Schiff Base Determines the Unique Inward Pumping of Xenorhodopsin

Juliane Weissbecker et al.

Summary: The new class of microbial rhodopsins, xenorhodopsins (XeRs), extends the versatility of this family by serving as inward H+ pumps, offering an alternative optogenetic tool that can activate electrically excitable cells independently of surrounding physiological conditions. Functional and spectroscopic characterization of NsXeR reveals insights into the photodynamic behavior, pH-dependent kinetics, and potential-dependent vectoriality of photocurrent transients. Mutational studies on the putative intracellular H+ acceptor D220 provide further understanding of the kinetically independent switching mechanism.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Chemistry, Medicinal

Interactive Interface for Graph-Based Analyses of Dynamic H-Bond Networks: Application to Spike Protein S

Malte Siemers et al.

Summary: Dynamic hydrogen-bond networks play a crucial role in protein conformational dynamics, especially in macromolecular protein complexes. Efficient algorithms are needed to analyze these interactions, as demonstrated in the analysis of the ectodomain dynamics of the SARS-CoV-2 protein S. The interface provided in this study allows for comprehensive analysis of protein dynamics and hydrophobic interactions.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Membrane matters: The impact of a nanodisc-bilayer or a detergent microenvironment on the properties of two eubacterial rhodopsins

Srividya Ganapathy et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Infrared Difference Spectroscopy of Proteins: From Bands to Bonds

Victor A. Lorenz-Fonfria

CHEMICAL REVIEWS (2020)

添加到收藏夹

Article Chemistry, Physical

Mechanism of Inward Proton Transport in an Antarctic Microbial Rhodopsin

Andrew Harris et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2020)

添加到收藏夹

Article Chemistry, Physical

Scalable molecular dynamics on CPU and GPU architectures with NAMD

James C. Phillips et al.

JOURNAL OF CHEMICAL PHYSICS (2020)

添加到收藏夹

Article Chemistry, Physical

Spectroscopic Study of Proton-Transfer Mechanism of Inward Proton-Pump Rhodopsin, Parvularcula oceani Xenorhodopsin

Keiichi Inoue et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2018)

添加到收藏夹

Article Chemistry, Physical

Spectroscopic characteristics of Rubricoccus marinus xenorhodopsin (RmXeR) and a putative model for its inward H+ transport mechanism

Saki Inoue et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2018)

添加到收藏夹

Article Spectroscopy

Protein dynamics observed by tunable mid-IR quantum cascade lasers across the time range from 10 ns to 1 s

Bernd-Joachim Schultz et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2018)

添加到收藏夹

Article Multidisciplinary Sciences

Orientation of non-spherical protonated water clusters revealed by infrared absorption dichroism

Jan O. Daldrop et al.

NATURE COMMUNICATIONS (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

FTIR Analysis of a Light-driven Inward Proton-pumping Rhodopsin at 77 K

Shota Ito et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Energetics and dynamics of a light-driven sodium-pumping rhodopsin

Carl-Mikael Suomivuori et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Inward H+ pump xenorhodopsin: Mechanism and alternative optogenetic approach

Vitaly Shevchenko et al.

SCIENCE ADVANCES (2017)

添加到收藏夹

Article Multidisciplinary Sciences

A natural light-driven inward proton pump

Keiichi Inoue et al.

NATURE COMMUNICATIONS (2016)

添加到收藏夹

Article Biophysics

Kinetic and Vibrational Isotope Effects of Proton Transfer Reactions in Channelrhodopsin-2

Tom Resler et al.

BIOPHYSICAL JOURNAL (2015)

添加到收藏夹

Review Chemistry, Multidisciplinary

Microbial and Animal Rhodopsins: Structures, Functions, and Molecular Mechanisms

Oliver P. Ernst et al.

CHEMICAL REVIEWS (2014)

添加到收藏夹

Article Multidisciplinary Sciences

Functional characterization of flavobacteria rhodopsins reveals a unique class of light-driven chloride pump in bacteria

Susumu Yoshizawa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

添加到收藏夹

Article Multidisciplinary Sciences

A light-driven sodium ion pump in marine bacteria

Keiichi Inoue et al.

NATURE COMMUNICATIONS (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Software News and Updates MDAnalysis: A Toolkit for the Analysis of Molecular Dynamics Simulations

Naveen Michaud-Agrawal et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)

添加到收藏夹

Article Multidisciplinary Sciences

Proton transfer via a transient linear water-molecule chain in a membrane protein

Erik Freier et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

添加到收藏夹

Article Chemistry, Multidisciplinary

Engineering an Inward Proton Transport from a Bacterial Sensor Rhodopsin

Akira Kawanabe et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

添加到收藏夹

Article Biochemistry & Molecular Biology

Time-resolved methods in biophysics. 10. Time-resolved FT-IR difference spectroscopy and the application to membrane proteins

Ionela Radu et al.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2009)

添加到收藏夹

Article Multidisciplinary Sciences

Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins

Nathan HyunJoong Joh et al.

NATURE (2008)

添加到收藏夹

Review Biochemistry & Molecular Biology

Infrared spectroscopy of proteins

Andreas Barth

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2007)

添加到收藏夹

Article Biophysics

A local area network of protonated water molecules

J Heberle

BIOPHYSICAL JOURNAL (2004)

添加到收藏夹

Article Biophysics

The assignment of the different infrared continuum absorbance changes observed in the 3000-1800-cm-1 region during the bacteriorhodopsin photocycle

F Garczarek et al.

BIOPHYSICAL JOURNAL (2004)

添加到收藏夹

Review Biochemistry & Molecular Biology

The influence of a transmembrane pH gradient on protonation probabilities of bacteriorhodopsin: The structural basis of the back-pressure effect

N Calimet et al.

JOURNAL OF MOLECULAR BIOLOGY (2004)

添加到收藏夹

Article Biochemistry & Molecular Biology

Proteorhodopsin is a light-driven proton pump with variable vectoriality

T Friedrich et al.

JOURNAL OF MOLECULAR BIOLOGY (2002)

添加到收藏夹

Article Biochemistry & Molecular Biology

Time-resolved FT-IR spectroscopic investigation of the pH-dependent proton transfer reactions in the E194Q mutant of bacteriorhodopsin

C Zscherp et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)

添加到收藏夹

Article Multidisciplinary Sciences

Bacterial rhodopsin:: Evidence for a new type of phototrophy in the sea

O Béjà et al.

SCIENCE (2000)

添加到收藏夹

Article Biochemistry & Molecular Biology

Origins of deuterium kinetic isotope effects on the proton transfers of the bacteriorhodopsin photocycle

LS Brown et al.

BIOCHEMISTRY (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.