期刊
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
卷 208, 期 1, 页码 33-40出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.molbiopara.2016.06.003
关键词
Parasite communications
资金
- Biotechnology and Biological Sciences Research Council [1276234] Funding Source: researchfish
Helminths are metazoan organisms many of which have evolved parasitic life styles dependent on sophisticated manipulation of the host environment. Most notably, they down-regulate host immune responses to ensure their own survival, by exporting a range of immuno-modulatory mediators that interact with host cells and tissues. While a number of secreted immunoregulatory parasite proteins have been defined, new work also points to the release of extracellular vesicles, or exosomes, that interact with and manipulate host gene expression. These recent results are discussed in the overall context of how helminths communicate effectively with the host organism. (C) 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license
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