相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structural insights into the activity regulation of full-length non-structural protein 1 from SARS-CoV-2
Ying Wang et al.
STRUCTURE (2023)
All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein
Ilya Frolov et al.
JOURNAL OF VIROLOGY (2023)
SARS-CoV-2 Nsp1 mediated mRNA degradation requires mRNA interaction with the ribosome
Soraya I. Shehata et al.
RNA BIOLOGY (2023)
Targeting stem-loop 1 of the SARS-CoV-2 5' UTR to suppress viral translation and Nsp1 evasion
Setu M. Vora et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
Mitoxantrone dihydrochloride, an FDA approved drug, binds with SARS-CoV-2 NSP1 C-terminal
Prateek Kumar et al.
RSC ADVANCES (2022)
MERS-CoV nsp1 impairs the cellular metabolic processes by selectively downregulating mRNAs in a novel granules
Zhaoyi Pan et al.
VIRULENCE (2022)
Site-specific recognition of SARS-CoV-2 nsp1 protein with a tailored titanium dioxide nanoparticle - elucidation of the complex structure using NMR data and theoretical calculation
Peter Agback et al.
NANOSCALE ADVANCES (2022)
Nonstructural Protein 1 of SARS Coronavirus Interacts with Stress Granule Protein G3BP1 and Accumulates in the Stress Granule
Anita Nag et al.
FASEB JOURNAL (2022)
Correlated sequence signatures are present within the genomic 5′UTR RNA and NSP1 protein in coronaviruses
Piotr Sosnowski et al.
RNA (2022)
The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression
Lucija Bujanic et al.
RNA (2022)
Parsing the role of NSP1 in SARS-CoV-2 infection
Tal Fisher et al.
CELL REPORTS (2022)
Drug targeting Nsp1-ribosomal complex shows antiviral activity against SARS-CoV-2
Mohammad Afsar et al.
ELIFE (2022)
Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography
Alberto Borsatto et al.
ELIFE (2022)
Cap-independent translation and a precisely located RNA sequence enable SARS-CoV-2 to control host translation and escape anti-viral response
Boris Slobodin et al.
NUCLEIC ACIDS RESEARCH (2022)
Synergistic interactions of repurposed drugs that inhibit Nsp1, a major virulence factor for COVID-19
Hung-Teh Kao et al.
SCIENTIFIC REPORTS (2022)
Two Ligand-Binding Sites on SARS-CoV-2 Non-Structural Protein 1 Revealed by Fragment-Based X-ray Screening
Shumeng Ma et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Structure of Nonstructural Protein 1 from SARS-CoV-2
Lauren K. Clark et al.
JOURNAL OF VIROLOGY (2021)
Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation
Christopher P. Lapointe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translation
Antonin Tidu et al.
RNA (2021)
Structural characterization of nonstructural protein 1 from SARS-CoV-2
Cameron Semper et al.
ISCIENCE (2021)
Mechanisms of Coronavirus Nsp1-Mediated Control of Host and Viral Gene Expression
Keisuke Nakagawa et al.
CELLS (2021)
1H, 13C, and 15N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein)
Ying Wang et al.
BIOMOLECULAR NMR ASSIGNMENTS (2021)
SARS-CoV-2 uses a multipronged strategy to impede host protein synthesis
Yaara Finkel et al.
NATURE (2021)
SARS-CoV-2 infection triggers widespread host mRNA decay leading to an mRNA export block
James M. Burke et al.
RNA (2021)
SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses
Abhik K. Banerjee et al.
CELL (2020)
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2
Matthias Thoms et al.
SCIENCE (2020)
FARFAR2: Improved De Novo Rosetta Prediction of Complex Global RNA Folds
Andrew Martin Watkins et al.
STRUCTURE (2020)
Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion
Zhou Shen et al.
VIRUSES-BASEL (2020)
SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation
Katharina Schubert et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)
Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA
Shuai Yuan et al.
MOLECULAR CELL (2020)
SARS coronavirus protein nsp1 disrupts localization of Nup93 from the nuclear pore complex
Garret N. Gomez et al.
BIOCHEMISTRY AND CELL BIOLOGY (2019)
A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence
Zhou Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Structural Basis for the Inhibition of Host Gene Expression by Porcine Epidemic Diarrhea Virus nsp1
Zhou Shen et al.
JOURNAL OF VIROLOGY (2018)
The Endonucleolytic RNA Cleavage Function of nsp1 of Middle East Respiratory Syndrome Coronavirus Promotes the Production of Infectious Virus Particles in Specific Human Cell Lines
Keisuke Nakagawa et al.
JOURNAL OF VIROLOGY (2018)
Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies
Andrea Bazzoli et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2017)
MERS coronavirus nsp1 participates in an efficient propagation through a specific interaction with viral RNA
Yutaka Terada et al.
VIROLOGY (2017)
Simultaneous Optimization of Biomolecular Energy Functions on Features from Small Molecules and Macromolecules
Hahnbeom Park et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2016)
Suppression of type I interferon production by porcine epidemic diarrhea virus and degradation of CREB-binding protein by nsp1
Qingzhan Zhang et al.
VIROLOGY (2016)
Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin
Kumari G. Lokugamage et al.
JOURNAL OF VIROLOGY (2015)
Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine
Jose M. Jimenez-Guardeno et al.
PLOS PATHOGENS (2015)
Continuous and Discontinuous RNA Synthesis in Coronaviruses
Isabel Sola et al.
ANNUAL REVIEW OF VIROLOGY, VOL 2 (2015)
Structure of Alphacoronavirus Transmissible Gastroenteritis Virus nsp1 Has Implications for Coronavirus nsp1 Function and Evolution
Anna M. Jansson
JOURNAL OF VIROLOGY (2013)
A Pareto-Optimal Refinement Method for Protein Design Scaffolds
Lucas Gregorio Nivon et al.
PLOS ONE (2013)
High-Resolution Comparative Modeling with RosettaCM
Yifan Song et al.
STRUCTURE (2013)
Severe Acute Respiratory Syndrome Coronavirus Protein nsp1 Is a Novel Eukaryotic Translation Inhibitor That Represses Multiple Steps of Translation Initiation
Kumari G. Lokugamage et al.
JOURNAL OF VIROLOGY (2012)
Severe Acute Respiratory Syndrome Coronavirus nsp1 Facilitates Efficient Propagation in Cells through a Specific Translational Shutoff of Host mRNA
Tomohisa Tanaka et al.
JOURNAL OF VIROLOGY (2012)
Alphacoronavirus Transmissible Gastroenteritis Virus nsp1 Protein Suppresses Protein Translation in Mammalian Cells and in Cell-Free HeLa Cell Extracts but Not in Rabbit Reticulocyte Lysate
Cheng Huang et al.
JOURNAL OF VIROLOGY (2011)
Viral subversion of the host protein synthesis machinery
Derek Walsh et al.
NATURE REVIEWS MICROBIOLOGY (2011)
RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite
Sarel J. Fleishman et al.
PLOS ONE (2011)
SARS Coronavirus nsp1 Protein Induces Template-Dependent Endonucleolytic Cleavage of mRNAs: Viral mRNAs Are Resistant to nsp1-Induced RNA Cleavage
Cheng Huang et al.
PLOS PATHOGENS (2011)
Nsp1 proteins of group I and SARS coronaviruses share structural and functional similarities
Yongjin Wang et al.
INFECTION GENETICS AND EVOLUTION (2010)
Suppression of Host Gene Expression by nsp1 Proteins of Group 2 Bat Coronaviruses
Yukinobu Tohya et al.
JOURNAL OF VIROLOGY (2009)
A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein
Wataru Kamitani et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells
Krishna Narayananj et al.
JOURNAL OF VIROLOGY (2008)
Severe acute respiratory syndrome coronavirus evades antiviral signaling: Role of nsp1 and rational design of an attenuated strain
Marc G. Wathelet et al.
JOURNAL OF VIROLOGY (2007)
Novel beta-barrel fold in the nuclear magnetic resonance structure of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus
Marcius S. Almeida et al.
JOURNAL OF VIROLOGY (2007)
Putative cis-acting stem-loops in the 5′ untranslated region of the severe acute respiratory syndrome coronavirus can substitute for their mouse hepatitis virus counterparts
Hyojeung Kang et al.
JOURNAL OF VIROLOGY (2006)
Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation
Wataru Kamitani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)