Acute Biological Changes in Gynecologic Surgeons during Surgery: A Prospective Study

Study Objective: To assess changes in biological measures of acute stress in surgeons during surgery in real-world settingsDesign: A prospective cohort study.Setting: A tertiary teaching hospital.Patients: 8 consultant and 9 training gynecologists. Intervention: A total of, 161 elective gynecologic surgeries of 3 procedures: laparoscopic hysterectomy, laparoscopic excision of endometriosis, or hysteroscopic myomectomy. Measurements and Main Results: Changes in surgeons' biological measures of acute stress while undertaking elective surgery. Salivary cortisol, mean and maximum heart rate (HR), and indices of the HR variability were recorded before and during surgery. From baseline to during surgery over the cohort, salivary cortisol decreased from 4.1 nmol/L to 3.6 nmol/L (p = .03), maximum HR increased from 101.8 beats per min (bpm) to 106.5 bpm (p <.01), root mean square of standard deviation decreased from 51.1 ms to 39.0 ms (p <.01), and standard deviation of beat-to-beat variability decreased from 73.7 to 59.8 ms (p <.01). Analysis of individual changes in stress by participant-surgery event by paired data graphs reveal inconsistent direction of change in all measures of biological stress despite stratification by surgical experience, role in surgery, level of training, or type of surgery performed.Conclusion: This study measured biometric stress changes at both a group and individual level in real-world, live surgical settings. Individual changes have not previously been reported and the variable direction of stress change by participant-surgery episode identified in this study demonstrates a problematic interpretation of mean cohort findings previously reported. Results from this study suggest that either live surgery with tight environment control or surgical simulation studies may identify what, if any, biological measures of stress can predict acute stress reactions during surgery. Journal of Minimally

Automated summary

This study aimed to assess the changes in biological measures of acute stress in surgeons during surgery in real-world settings. The results showed that salivary cortisol decreased, maximum heart rate increased, and heart rate variability decreased at the group level. However, individual changes in stress showed inconsistent directions. These findings demonstrate the problematic interpretation of mean cohort findings previously reported in stress research.