4.7 Article

Distinct retinoic gene signatures discriminate Merkel cell polyomavirus-positive from -negative Merkel cell carcinoma cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Virology

MicroRNA dysregulations in Merkel cell carcinoma: Molecular mechanisms and clinical applications

Chiara Mazziotta et al.

Summary: Merkel cell carcinoma has two distinct etiologies, one caused by Merkel cell polyomavirus and another induced by UV exposure. This review discusses the dysregulation of miRNAs in MCC and their potential clinical application as diagnostic and prognostic biomarkers, aiming to improve MCC options for diagnosis, prognosis, and treatment.

JOURNAL OF MEDICAL VIROLOGY (2023)

Editorial Material Pathology

Evidence of an epithelial origin of Merkel cell carcinoma

Kervarrec Thibault

MODERN PATHOLOGY (2022)

Article Pathology

Genomic evidence suggests that cutaneous neuroendocrine carcinomas can arise from squamous dysplastic precursors

Paul W. Harms et al.

Summary: MCC and SCCIS show significant overlap in gene mutations, with no unique gene mutations found in all cases of MCC. Transcriptome analysis reveals large differences in gene expression between MCC and SCCIS, including epidermal markers and immune genes. Immunohistochemistry studies show increased expression of SOX2 in the MCC component.

MODERN PATHOLOGY (2022)

Review Oncology

The Role of Histone Post-Translational Modifications in Merkel Cell Carcinoma

Chiara Mazziotta et al.

Summary: This article reviews the recent progress in understanding the etiology and treatment of Merkel Cell Carcinoma (MCC), focusing on the role of histone post-translational modifications (PTMs) and their potential as diagnostic and therapeutic markers.

FRONTIERS IN ONCOLOGY (2022)

Review Biochemistry & Molecular Biology

The Use of Retinoids for the Prevention and Treatment of Skin Cancers: An Updated Review

Brandon Ramchatesingh et al.

Summary: Retinoids, natural or synthetic derivatives of vitamin A, are effective for the prevention and treatment of non-melanoma skin cancers. They regulate biological processes in the skin and suppress skin carcinogenesis. Retinoids have been widely used in clinical practice and approved for the management of non-melanoma skin cancers.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Dentistry, Oral Surgery & Medicine

FGF8 induces epithelial-mesenchymal transition and promotes metastasis in oral squamous cell carcinoma

Yilong Hao et al.

Summary: The study reveals that upregulated FGF8 in oral squamous cell carcinoma tissues is associated with various clinicopathologic parameters and enhances the invasive capability and metastasis of cancer cells, indicating an important role of FGF8 in the development of oral squamous cell carcinoma.

INTERNATIONAL JOURNAL OF ORAL SCIENCE (2021)

Article Microbiology

High Human Papillomavirus DNA loads in Inflammatory Middle Ear Diseases

Nicola Malagutti et al.

PATHOGENS (2020)

Review Biochemistry & Molecular Biology

Functional characterization of SOX2 as an anticancer target

Shizhen Zhang et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

Review Dermatology

The Biology and Clinical Features of Cutaneous Polyomaviruses

Khang D. Nguyen et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2019)

Article Multidisciplinary Sciences

Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition

Alexis Harold et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Oncology

Developmental pathways associated with cancer metastasis: Notch, Wnt, and Hedgehog

Armel Herve Nwabo Kamdje et al.

CANCER BIOLOGY & MEDICINE (2017)

Article Oncology

Molecular mechanisms of OLIG2 transcription factor in brain cancer

Igor F. Tsigelny et al.

ONCOTARGET (2016)