Confirmatory biomarker diagnostic studies are not needed when transitioning from NAFLD to MASLD

Article Gastroenterology & Hepatology

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

Mary E. Rinella et al.

HEPATOLOGY (2023)

Article Gastroenterology & Hepatology

Validation of the new 2021 EASL algorithm for the noninvasive diagnosis of advanced fibrosis in NAFLD

Clemence M. Canivet et al.

Summary: This study validates the algorithm proposed by EASL in its latest 2021 guidelines for the diagnosis of advanced fibrosis in NAFLD. The algorithm shows high accuracy in noninvasive tests and effectively reduces the need for liver biopsy.

HEPATOLOGY (2023)

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Article Gastroenterology & Hepatology

Reliability Criteria of Two-Dimensional Shear Wave Elastography: Analysis of 4277 Measurements in 788 Patients

Anita Paisant et al.

Summary: This study aimed to determine the reliability criteria and the number of necessary reliable measurements for 2D-SWE, and found that mean stiffness and coefficient of variation were independent predictors of bridging fibrosis or cirrhosis. According to the new criteria, a 2D-SWE examination should include three reliable measurements.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2022)

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Article Endocrinology & Metabolism

American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD)

Kenneth Cusi et al.

Summary: This article provides evidence-based recommendations for the diagnosis and management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) for endocrinologists, primary care clinicians, and other stakeholders. The guideline includes 34 evidence-based clinical practice recommendations and contains relevant citations.

ENDOCRINE PRACTICE (2022)

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Article Gastroenterology & Hepatology

Transient Versus Two-Dimensional Shear-Wave Elastography in a Multistep Strategy to Detect Advanced Fibrosis in NAFLD

Christophe Cassinotto et al.

Summary: This study found that in patients with NAFLD, 2D-SWE-SSI is as accurate as VCTE for diagnosing advanced liver fibrosis. A three-step strategy in selected patients greatly reduced the need for liver biopsy while maintaining excellent accuracy.

HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis-2021 update

Annalisa Berzigotti et al.

Summary: The article provides the latest update to the EASL Clinical Practice Guidelines on the use of non-invasive tests for assessing liver disease severity and prognosis, with a focus on topics with relevant evidence published in the last 5 years.

JOURNAL OF HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology