期刊
MINI-REVIEWS IN ORGANIC CHEMISTRY
卷 13, 期 5, 页码 377-388出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1570193X13666160826154159
关键词
4-Thiazolidinone; anticancer activity; cytotoxic; diflunisal; etodolac; flurbiprofen; synthesis
4-Thiazolidinones are sulphur analogues of oxazolidines. They are heterocyclic ring systems which have been explored for their antimicrobial, anticancer, anti-HCV, antifungal, anticonvulsant, antituberculosis, and other activities. While some earlier reviews on the biological activities of this ring system have been reported, the present review describes more recent synthetic strategies and medicinal aspects of 4-thiazolidinones as anticancer agents reported during the past few years (2010-2016).
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