4.6 Article

Investigation of the effects of sugar type on the formation of ?-dicarbonyl compounds in jams under in vitro digestive system model

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ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jfca.2023.105301

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Jams; Diabetic; Sugar; ?-Dicarbonyl Compounds; in vitro

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The study aimed to determine the effects of different sugar types on the formation of alpha-dicarbonyl compounds (alpha-DCs) in jams under in vitro digestive system. High Performance Liquid Chromatography was used to analyze glyoxal (GO) and methylglyoxal (MGO) levels in jams before and after in vitro digestion. The results showed that in vitro digestion significantly increased the formation of GO and MGO in jams, particularly in diabetic jams and homemade jams. Jams containing sugar alcohols may have a higher potential for the formation of AGEs precursors after in vitro digestion, posing a problem for diabetic individuals.
The present study aimed to determine the effects of sugar type on the formation of alpha-dicarbonyl compounds (alpha-DCs) in jams under in vitro digestive system. Glyoxal (GO) and methylglyoxal (MGO) levels were analyzed with High Performance Liquid Chromatography in jams before and after in vitro digestion. Initial GO and MGO values in jam samples were ranged between 184.38 and 615.94 mu g/100 g, and 63.71 and 2978.04 mu g/100 g, respectively. After in vitro digestion, the GO and MGO values were increased up to 1616.59 mu g/100 g and 3170.39 mu g/100 g, respectively. At initial, diabetic jams and homemade jams had relatively low alpha-DCs content than other jam samples. In vitro digestion had strongly increased the GO and MGO formation in jams, especially in diabetic jams and homemade jams. Sample containing sugar alcohols may have more potential to form AGEs precursors after in vitro digestion, which could be a problem for diabetic people.

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