Coumarin Based Fluorescent Probe for Detecting Heavy Metal Ions

Heavy metals such as Iron, Copper, and Zinc are micro-essential trace metal and involve animportant biological role, but it quickly turns toxic at exceeding the permissible limit, causing gastrointestinal irritation, liver, bone, and kidney damage, as well as disorders including Wilson's, Parkinson's, and Alzheimer's. It is important to detect the metal ions as well as their concentration quickly and affordable cost using organic probes. Among the organic probes,the coumarin fluorescent probe shows a very prominent candidate with heavy metal ions. Therefore, in the present review, we reviewed the very recent literature the identify the heavy metals using modified coumarin fluorescent probes. Readers will get information quickly about the method of preparation of modified coumarin core and their use as fluorescent probes with heavy metals using absorption and emission spectroscopic methods along with the probable mechanistic pathway of detection.

Automated summary

Heavy metals such as Iron, Copper, and Zinc play important biological roles, but become toxic at high levels, causing various health issues. Detecting metal ions and their concentration using organic probes is crucial. Among them, coumarin fluorescent probes are a promising candidate for heavy metal detection. This review focuses on the recent literature on modified coumarin fluorescent probes for identifying heavy metals. It provides information on preparation methods, spectroscopic detection techniques, and the mechanistic pathway of detection.