☆ 4.6 Article

Salivary metabolomic profile associated with cariogenic risk in children

JOURNAL OF DENTISTRY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Dentistry, Oral Surgery & Medicine

Salivary microbiome and metabolome analysis of severe early childhood caries

Kai Li et al.

BMC Oral Health (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Metabolic Profile of Whole Unstimulated Saliva in Patients with Sjogren's Syndrome

Giacomo Setti et al.

Summary: The aim of this study is to compare the salivary metabolomes of pSS patients with healthy controls using NMR analysis. About 50 metabolites were detected and assigned, and the results indicated that the metabolite composition of saliva can effectively differentiate pSS patients from healthy controls.

METABOLITES (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Identification of a Biomarker Panel for Diagnosis of Early Childhood Caries Using Salivary Metabolic Profile

Seonghye Kim et al.

Summary: Several studies have shown that nuclear magnetic resonance (NMR) metabolic profiles can differentiate patients with caries from healthy individuals. This study aimed to identify a salivary metabolite biomarker panel for early childhood caries (ECC). Saliva samples from children with and without caries were analyzed using NMR spectroscopy, and specific metabolites were identified that could detect ECC. An optimal biomarker panel comprising formate, lactate, proline, and glycine was developed, which showed improved diagnostic performance for ECC compared to a single metabolite.

METABOLITES (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

HMDB 5.0: the Human Metabolome Database for 2022

David S. Wishart et al.

Summary: The Human Metabolome Database (HMDB) has been providing comprehensive information about human metabolites since 2007, and has undergone significant improvements and upgrades in its latest update, HMDB 5.0. These improvements include an increase in the number of metabolite entries, enhancements to metabolite descriptions, new visualization tools, and more accurately predicted spectral data sets. These upgrades are aimed at improving the usability and potential applications of the HMDB in various fields, including human metabolomics, exposomics, lipidomics, nutritional science, biochemistry, and clinical chemistry.

NUCLEIC ACIDS RESEARCH (2022)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Metabolic differences of the oral microbiome related to dental caries - A pilot study

Yinuo Wang et al.

Summary: This study investigated the composition and functions discrepancy of supragingival plaque associated with active deciduous teeth caries in mixed dentitions. The results showed no significant differences in microbiome composition between caries and caries-free groups, but metabolome analysis identified glucose metabolism and oxidative stress as related to dental caries in mixed dentitions.

ARCHIVES OF ORAL BIOLOGY (2022)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Understanding dental caries as a non-communicable and behavioral disease: Management implications

Rodrigo A. Giacaman et al.

Summary: This article reviews the paradigm shift in the conceptualization of caries as a non-communicable disease and discusses its appropriate management. Dental caries has transitioned from being considered as a communicable and infectious disease to an ecological and non-communicable disease, closely related to behavior and lifestyle. Environmental factors, such as the frequent intake of sugars, disrupt the symbiosis of the dental biofilm, leading to the initiation and progression of caries lesions. As an NCD, dental caries shares similarities with other non-communicable diseases such as cardiovascular and chronic respiratory diseases, cancer, and diabetes.

FRONTIERS IN ORAL HEALTH (2022)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Metabolic differences of the oral microbiome related to dental caries - A pilot study

Yinuo Wang et al.

Summary: The study aimed to investigate the composition and functions discrepancy of supragingival plaque associated with active deciduous teeth caries in mixed dentitions. Results showed similar microbiota composition between caries and caries-free groups, but metabolomic analysis revealed biochemical metabolites related to caries status and positively correlated with dominant bacteria.

ARCHIVES OF ORAL BIOLOGY (2022)

添加到收藏夹

Article Immunology

Bacterial Composition and Metabolomics of Dental Plaque From Adolescents

Kristian Havsed et al.

Summary: This study identified specific bacterial species and metabolites in dental plaque samples associated with caries risk, suggesting that caries risk assessment should consider the functional adaptation and metabolic output of bacteria.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

添加到收藏夹

Article Microbiology

The bacterial microbiome and metabolome in caries progression and arrest

Thamirys da Costa Rosa et al.

Summary: This experimental study investigated longitudinal changes in bacterial microbiome and metabolome associated with enamel caries lesion progression and arrest. The results revealed the association of specific microbes and metabolites with caries progression and arrest, providing new insights into the role of biofilm in caries development. These findings offer promising candidate biomarkers for future validation studies.

JOURNAL OF ORAL MICROBIOLOGY (2021)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Terminology of Dental Caries and Dental Caries Management: Consensus Report of a Workshop Organized by ORCA and Cariology Research Group of IADR

Vita Machiulskiene et al.

CARIES RESEARCH (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Targeted metabolomics of pellicle and saliva in children with different caries activity

Annika Schulz et al.

SCIENTIFIC REPORTS (2020)

添加到收藏夹

Article Microbiology

Integrated hypothesis of dental caries and periodontal diseases

Bente Nyvad et al.

JOURNAL OF ORAL MICROBIOLOGY (2020)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Saliva NMR metabolomics: Analytical issues in pediatric oral health research

Joana L. Pereira et al.

ORAL DISEASES (2019)

添加到收藏夹

Article Biochemical Research Methods

NMR metabolomics: A look ahead

David S. Wishart

JOURNAL OF MAGNETIC RESONANCE (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

NMR Spectroscopy for Metabolomics Research

Abdul-Hamid Emwas et al.

METABOLITES (2019)

添加到收藏夹

Article Medicine, Research & Experimental

Metabolomic Status of The Oral Cavity in Chronic Periodontitis

Katarzyna Gawron et al.

IN VIVO (2019)

添加到收藏夹

Article Microbiology

Determining bacterial and host contributions to the human salivary metabolome

Alexander Gardner et al.

JOURNAL OF ORAL MICROBIOLOGY (2019)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Salivary secretion in health and disease

A. M. L. Pedersen et al.

JOURNAL OF ORAL REHABILITATION (2018)

添加到收藏夹

Article Biochemical Research Methods

Developing and Standardizing a Protocol for Quantitative Proton Nuclear Magnetic Resonance (1H NMR) Spectroscopy of Saliva

Alexander Gardner et al.

JOURNAL OF PROTEOME RESEARCH (2018)

添加到收藏夹

Article Multidisciplinary Sciences

Using NMR in saliva to identify possible biomarkers of glioblastoma and chronic periodontitis

Alberto Garcia-Villaescusa et al.

PLOS ONE (2018)

添加到收藏夹

Article Neurosciences

Diagnostic Biomarkers of Alzheimer's Disease as Identified in Saliva using H-1 NMR-Based Metabolomics

Ali Yilmaz et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

添加到收藏夹

Article Multidisciplinary Sciences

The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity

Eric Neyraud et al.

SCIENTIFIC REPORTS (2017)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Oral health-related quality-of-life scores differ by socioeconomic status and caries experience

Benjamin W. Chaffee et al.

COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY (2017)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

The physiology of salivary secretion

Gordon B. Proctor

PERIODONTOLOGY 2000 (2016)

添加到收藏夹

Article Endocrinology & Metabolism

The human saliva metabolome

Zerihun T. Dame et al.

METABOLOMICS (2015)

添加到收藏夹

Article Endocrinology & Metabolism

Longitudinal evaluation of salivary profile from children with dental caries before and after treatment

Tatiana K. S. Fidalgo et al.

METABOLOMICS (2015)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Current metabolomics: Technological advances

Sastia P. Putri et al.

JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Fatty Acid Profile of the Initial Oral Biofilm (Pellicle): an In-Situ Study

Marco Reich et al.

LIPIDS (2013)

添加到收藏夹

Article Endocrinology & Metabolism

Salivary metabolite signatures of children with and without dental caries lesions

Tatiana K. S. Fidalgo et al.

METABOLOMICS (2013)

添加到收藏夹

Review Biochemical Research Methods

Advances in metabolite identification

David S. Wishart

BIOANALYSIS (2011)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Association of free amino acids with caries experience and mutans streptococci levels in whole saliva of children with early childhood caries

Cristiane S. R. Fonteles et al.

ARCHIVES OF ORAL BIOLOGY (2009)

添加到收藏夹

Article Chemistry, Applied

Lipids in Human Parotid Saliva with Regard to Caries Experience

Yumiko Tomita et al.

JOURNAL OF OLEO SCIENCE (2008)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.