Automated and semi-automated packed sorbent solid phase (micro) extraction methods for extraction of organic and inorganic pollutants

In this study, the packed sorbent solid phase (micro) extraction methods from manual to automated modes are reviewed. The automatic methods have several remarkable advantages such as high sample throughput, reproducibility, sensitivity, and extraction efficiency. These methods include solid-phase extraction, pipette tip micro-solid phase extraction, microextraction by packed sorbent, in-tip solid phase microextraction, in-tube solid phase microextraction, lab-on-a-chip, and lab-on-a-valve. The recent application of these methods for the extraction of organic and inorganic compounds are discussed. Also, the combination of novel technologies (3D printing and robotic platforms) with the (semi)automated methods are investigated as the future trend.

Automated summary

This study reviews the packed sorbent solid phase (micro) extraction methods from manual to automated modes. The automated methods offer remarkable advantages such as high sample throughput, reproducibility, sensitivity, and extraction efficiency. Various methods including solid-phase extraction, pipette tip micro-solid phase extraction, microextraction by packed sorbent, in-tip solid phase microextraction, in-tube solid phase microextraction, lab-on-a-chip, and lab-on-a-valve are discussed, along with their recent applications for the extraction of organic and inorganic compounds. The combination of novel technologies like 3D printing and robotic platforms with (semi)automated methods are also investigated as the future trend.