期刊
JOURNAL OF CHROMATOGRAPHY A
卷 1700, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.chroma.2023.464032
关键词
Chiral metal -organic frameworks; CMOFs composites; Chiral separation; Chiral stationary phase; High-performance liquid chromatography
Chiral metal organic frameworks (CMOFs), with customizable combination of metal nodes and organic ligands, have attracted increasing attention due to their highly ordered crystal structure and rich adjustable chiral structure. This review discusses the progress of CMOFs and their different types of composites used as chiral stationary phases (CSPs) in liquid chromatography for enantioseparation. The characteristics of CMOFs and their composites are summarized, aiming to provide new ideas for the development of CMOFs with better performance and further promote the application of CMOFs materials in enantioselective high-performance liquid chromatography (HPLC).
Chiral metal organic frameworks (CMOFs) are a kind of crystal porous framework material that has attracted increasing attention due to the customizable combination of metal nodes and organic ligands. In particular, the highly ordered crystal structure and rich adjustable chiral structure make it a promising material for developing new chiral separation material systems. In this review, the progress of CMOFs and their different types of composites used as chiral stationary phases (CSPs) in liquid chromatography for enantioseparation are discussed. The characteristics of CMOFs and their composites are summarized, aiming to provide new ideas for the development of CMOFs with better performance and further promote the application of CMOFs materials in enantioselective high-performance liquid chromatography (HPLC). (c) 2023 Elsevier B.V. All rights reserved.
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