4.7 Review

The role of GPLD1 in chronic diseases

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Cap-independent translation of GPLD1 enhances markers of brain health in long-lived mutant and drug-treated mice

Xinna Li et al.

Summary: Glycosylphosphatidylinositol-specific phospholipase D1 (GPLD1) may play an important role in maintaining cognitive function in aging mice by increasing levels of hippocampal brain-derived neurotrophic factor (BDNF) and doublecortin (DCX), potentially through cap-independent translation (CIT) regulation.

AGING CELL (2022)

Review Oncology

uPAR, beyond regulating physiological functions, has orchestrated roles in cancer (Review)

Liang Wang et al.

Summary: This review summarizes the function, signaling pathways, and targeted therapeutic strategies of uPAR in cancer, particularly focusing on immunotherapy targeting uPAR. It also objectively evaluates the value of this classic molecular pathway for future study, considering its differential roles in non-cancer and cancer tissues.

INTERNATIONAL JOURNAL OF ONCOLOGY (2022)

Article Endocrinology & Metabolism

Serum glypican4 and glycosylphosphatidylinositol-specific phospholipase D levels are associated with adipose tissue insulin resistance in obese subjects with different glucose metabolism status

K. Zhang et al.

Summary: The study demonstrated that serum levels of GPC4 and GPLD1 in obese subjects are associated with glucose metabolism status and adipose tissue insulin resistance, with GPC4 positively correlated with GPLD1 and independently and positively associated with Adipo-IR.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2021)

Article Endocrinology & Metabolism

Combined proteomic and lipidomic studies in Pompe disease allow a better disease mechanism understanding

Anna Sidorina et al.

Summary: Pompe disease is caused by deficiency of acid alpha-glucosidase, resulting in glycogen accumulation in lysosomes. Proteomic and lipidomic analysis revealed significant differences and involvement of multiple cellular functions in PD, indicating potential abnormal phospholipid metabolism and GPI-anchor system involvement.

JOURNAL OF INHERITED METABOLIC DISEASE (2021)

Review Oncology

Prostaglandin E2 Receptor 4 (EP4) as a Therapeutic Target to Impede Breast Cancer-Associated Angiogenesis and Lymphangiogenesis

Guillermo Antonio De Paz Linares et al.

Summary: The formation of new blood and lymphatic vessels are essential for cancer progression, especially in breast cancer. Inflammation mediated by COX-2 plays a crucial role in promoting angiogenesis and lymphangiogenesis in breast cancer. Targeting the COX-2/EP4 pathway shows promising potential for breast cancer therapy.

CANCERS (2021)

Article Biochemistry & Molecular Biology

Interaction of Full-Length Glycosylphosphatidylinositol-Anchored Proteins with Serum Proteins and Their Translocation to Cells In Vitro Depend on the (Pre-)Diabetic State in Rats and Humans

Gunter A. Mueller et al.

Summary: The release of GPI-APs into the blood in response to metabolic stress and aging is influenced by interaction with serum proteins like GPLD1, affecting cell surface integrity. Upregulation of GPLD1 interaction with GPI-AP complexes is associated with hyperglycemic/hyperinsulinemic conditions. Serum proteins could modulate the translocation and lysis of GPI-APs.

BIOMEDICINES (2021)

Review Endocrinology & Metabolism

New Horizon: Exercise and a Focus on Tissue-Brain Crosstalk

Logan K. Townsend et al.

Summary: Exercise has been shown to improve brain health and cognitive function, with recent research focusing on how peripheral tissues communicate with the brain through circulating factors produced during exercise. This crosstalk plays a crucial role in the adaptations that occur in the brain in response to physical activity.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2021)

Article Endocrinology & Metabolism

Latent Autoimmune Diabetes of Adults (LADA) Is Likely to Represent a Mixed Population of Autoimmune (Type 1) and Nonautoimmune (Type 2) Diabetes

Angus G. Jones et al.

Summary: LADA, diagnosed after age 35, presents clinical features similar to type 2 diabetes but with type 1 diabetes-associated islet autoantibodies. The current definition of LADA identifies a group with features intermediate between typical type 1 and type 2 diabetes, leading to difficulties in classification. Improved approaches are needed to increase test specificity and better understand the detailed pathophysiological components of late-onset autoimmune diabetes.

DIABETES CARE (2021)

Article Endocrinology & Metabolism

Upregulated phospholipase D activity toward glycosylphosphatidylinositol-anchored proteins in micelle-like serum complexes in metabolically deranged rats and humans

Guenter A. Mueller et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2020)

Article Biochemistry & Molecular Biology

Galectin 3?binding protein suppresses amyloid-? production by modulating ?-cleavage of amyloid precursor protein

Tsuneyoshi Seki et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Cell Biology

Age-dependent membrane release and degradation of full-length glycosylphosphatidylinositol-anchored proteins in rats

Guenter A. Mueller et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2020)

Review Biochemistry & Molecular Biology

Pompe Disease: New Developments in an Old Lysosomal Storage Disorder

Naresh K. Meena et al.

BIOMOLECULES (2020)

Review Gastroenterology & Hepatology

Neoadjuvant radiotherapy for rectal cancer management

Gerard Feeney et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2019)

Article Endocrinology & Metabolism

Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity

Shigeki Masuda et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2019)

Article Endocrinology & Metabolism

MASP1, THBS1, GPLD1 and ApoA-IV are novel biomarkers associated with prediabetes: the KORA F4 study

Christine von Toerne et al.

DIABETOLOGIA (2016)

Article Geriatrics & Gerontology

Skeletal muscle ceramide species in men with abdominal obesity

M. P. de la Maza et al.

JOURNAL OF NUTRITION HEALTH & AGING (2015)

Article Biochemical Research Methods

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

Linn Fagerberg et al.

MOLECULAR & CELLULAR PROTEOMICS (2014)

Article Nutrition & Dietetics

Low serum eicosapentaenoic acid/arachidonic acid ratio in male subjects with visceral obesity

Kana Inoue et al.

NUTRITION & METABOLISM (2013)

Article Biochemistry & Molecular Biology

Genetic variation of GPLD1 associates with serum GPI-PLD levels: A preliminary study

Mark A. Deeg et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2012)

Review Biochemistry & Molecular Biology

MYC on the Path to Cancer

Chi V. Dang

Article Biotechnology & Applied Microbiology

Depigmenting Effect of Kojic Acid Esters in Hyperpigmented B16F1 Melanoma Cells

Ahmad Firdaus B. Lajis et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012)

Review Oncology

Carcinoembryonic antigen (CEA) as tumor marker in lung cancer

M. Grunnet et al.

LUNG CANCER (2012)

Article Multidisciplinary Sciences

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

Naoki Kumashiro et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Biochemistry & Molecular Biology

Synthetic Inositol Phosphoglycans Related to GPI Lack Insulin-Mimetic Activity

Marie-Lyn Hecht et al.

ACS CHEMICAL BIOLOGY (2010)

Article Endocrinology & Metabolism

Glycosylphosphatidylinositol-specific phospholipase D improves glucose tolerance

Nandita S. Raikwar et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2010)

Review Biochemistry & Molecular Biology

The opposing effects of n-3 and n-6 fatty acids

Gerd Schmitz et al.

PROGRESS IN LIPID RESEARCH (2008)

Article Medical Laboratory Technology

Statin therapy reduces serum levels of glycosylphosphatidylinositol-specific phospholipase D

Mark A. Deeg et al.

TRANSLATIONAL RESEARCH (2007)

Article Medicine, Research & Experimental

Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease

Varman T. Samuel et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Endocrinology & Metabolism

Glycosylphosphatidylinositol-specific phospholipase D in nonalcoholic fatty liver disease: A preliminary study

Naga Chalasani et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)

Letter Oncology

High expression of CD59 and CD55 on benign and malignant plasma cells

T Alcindor et al.

LEUKEMIA & LYMPHOMA (2006)

Article Endocrinology & Metabolism

Glycosylphosphatidylinositol-specific phospholipase D influences triglyceride-rich lipoprotein metabolism

NS Raikwar et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)

Article Biochemistry & Molecular Biology

Cleavage of carcinoembryonic antigen induces metastatic potential in colorectal carcinoma

Y Yamamoto et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Article Endocrinology & Metabolism

Insulin resistance is associated with increased serum levels of glycosylphosphatidylinositol-specific phospholipase D

TA Kurtz et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2004)

Review Biochemistry & Molecular Biology

The many faces of c-MYC

S Pelengaris et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)

Article Oncology

GPI-specific phospholipase D mRNA expression in tumor cells of different malignancy

XT He et al.

CLINICAL & EXPERIMENTAL METASTASIS (2002)