4.6 Article

MiR-222-3p suppresses C2C12 myoblast proliferation and differentiation via the inhibition of IRS-1/PI3K/Akt pathway

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Endocrinology & Metabolism

Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4

Satoshi Yamaguchi et al.

Summary: MiR-221-3p and miR-222-3p are upregulated in obesity, and overexpression of miR-222-3p may enhance adipogenesis.

FRONTIERS IN ENDOCRINOLOGY (2022)

Article Biochemistry & Molecular Biology

Selenoprotein K protects skeletal muscle from damage and is required for satellite cells-mediated myogenic differentiation

Shengchen Wang et al.

Summary: This study reveals the important role of SelK in skeletal muscle myogenesis. Loss of SelK delays skeletal muscle regeneration and inhibits the development of myoblasts into myotubes. In addition, SelK deficiency leads to increased cellular stress, oxidative stress, autophagy, and apoptosis. Supplementation with specific inhibitors partially restores the differentiation potential and formation of myotubes.

REDOX BIOLOGY (2022)

Article Medicine, Research & Experimental

Upregulation of miR-222-3p alleviates the symptom of aortic dissection through targeting STAT3

Tianci Chai et al.

Summary: This study investigates the differential expression of miRNAs in Aortic dissection (AD) and explores the downstream mechanisms in regulating AD. The upregulation of miR-222-3p attenuates the progression of AD by targeting STAT3, inhibiting stress fiber formation, abnormal migration, proliferation, and apoptosis of HVSMCs induced by PDGF-BB.

LIFE SCIENCES (2022)

Article Oncology

Targeting IRS-1/2 in Uveal Melanoma Inhibits In Vitro Cell Growth, Survival and Migration, and In Vivo Tumor Growth

Chandrani Chattopadhyay et al.

Summary: Researchers found that inhibiting the IGF-1 signaling pathway can reduce cell survival and migration, while promoting apoptosis in UM. In vivo models also showed a decrease in tumor growth with this treatment.

CANCERS (2022)

Review Cell Biology

Sestrin2 and mitochondrial quality control: Potential impact in myogenic differentiation

Luiz F. Piochi et al.

Summary: Mitochondria play a crucial role in myogenesis and their interaction with myogenic differentiation needs further exploration. SESN2 may act as a regulator of mitochondrial quality control under stress conditions induced by ROS, suggesting its potential involvement in myogenic differentiation.

AGEING RESEARCH REVIEWS (2021)

Article Agriculture, Multidisciplinary

The Crosstalk between Autophagy and Apoptosis Is Necessary for Myogenic Differentiation

Aiwen Jiang et al.

Summary: This study found that during myogenic differentiation, the level of autophagy was consistent with apoptosis, with increased apoptosis activating autophagy, which in turn inhibited apoptosis to prevent excessive cell death and maintain cell stability. The interaction between autophagy and apoptosis determines the balance of cell death and survival during skeletal muscle cell differentiation.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Review Cell Biology

RNA-Binding Proteins in the Post-transcriptional Control of Skeletal Muscle Development, Regeneration and Disease

De-Li Shi et al.

Summary: Embryonic myogenesis is a complex process regulated by RNA-binding proteins, which play a crucial role in controlling different steps to ensure the proliferation and differentiation of muscle cells. Dysfunctions of RNA-binding proteins can affect muscle development and homeostasis, leading to defects in motor neurons or the neuromuscular junction, resulting in muscle degeneration and neuromuscular disease.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Biotechnology & Applied Microbiology

Exogenous miR-29a Attenuates Muscle Atrophy and Kidney Fibrosis in Unilateral Ureteral Obstruction Mice

Bin Wang et al.

HUMAN GENE THERAPY (2020)

Review Biochemistry & Molecular Biology

Systems and Synthetic microRNA Biology: From Biogenesis to Disease Pathogenesis

Hironori Matsuyama et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Cell Biology

Mechanisms regulating myoblast fusion: A multilevel interplay

Lilya Lehka et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2020)

Article Medicine, Research & Experimental

miR-324-5p Inhibits C2C12 cell Differentiation and Promotes Intramuscular Lipid Deposition through lncDUM and PM20D1

Yihao Liu et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

Review Biochemical Research Methods

Trends in the development of miRNA bioinformatics tools

Liang Chen et al.

BRIEFINGS IN BIOINFORMATICS (2019)

Editorial Material Biochemistry & Molecular Biology

Toward a Comprehensive View of MicroRNA Biology

Yao Xiao et al.

MOLECULAR CELL (2019)

Article Biochemistry & Molecular Biology

Exosomal miR-21 regulates the TETs/PTENp1/PTEN pathway to promote hepatocellular carcinoma growth

Liang-qi Cao et al.

MOLECULAR CANCER (2019)

Article Biochemistry & Molecular Biology

miR-10b-5p Regulates C2C12 Myoblasts Proliferation and Differentiation

Guihua Ge et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Exogenous miR-26a suppresses muscle wasting and renal fibrosis in obstructive kidney disease

Aiqing Zhang et al.

FASEB JOURNAL (2019)

Article Biotechnology & Applied Microbiology

Exosome-Mediated miR-29 Transfer Reduces Muscle Atrophy and Kidney Fibrosis in Mice

Haidong Wang et al.

MOLECULAR THERAPY (2019)

Article Geriatrics & Gerontology

Systemic and Local Phenotypes of Barium Chloride Induced Skeletal Muscle Injury in Mice

Hee-Won Jung et al.

ANNALS OF GERIATRIC MEDICINE AND RESEARCH (2019)

Article Physiology

Akt1 deficiency diminishes skeletal muscle hypertrophy by reducing satellite cell proliferation

Nobuki Moriya et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2018)

Article Medicine, Research & Experimental

MiR-204-5p regulates C2C12 myoblast differentiation by targeting MEF2C and ERRγ

Xiao Cheng et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Medicine, Research & Experimental

Myogenic regulatory factors: The orchestrators of myogenesis after 30 years of discovery

Hasan A. Asfour et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2018)

Article Cell Biology

miR-152 regulates the proliferation and differentiation of C2C12 myoblasts by targeting E2F3

Mailin Gan et al.

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2018)

Article Allergy

MicroRNA

Thomas X. Lu et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

Article Clinical Neurology

Update on muscle disease

J. Witherick et al.

JOURNAL OF NEUROLOGY (2018)

Article Multidisciplinary Sciences

Identification of microRNA that represses IRS-1 expression in liver

Kaoru Ono et al.

PLOS ONE (2018)

Review Biochemistry & Molecular Biology

The Role of AMPK in the Regulation of Skeletal Muscle Size, Hypertrophy, and Regeneration

David M. Thomson

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Multidisciplinary Sciences

miR-29b contributes to multiple types of muscle atrophy

Jin Li et al.

NATURE COMMUNICATIONS (2017)

Correction Medicine, Research & Experimental

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism (Retracion of vol 115, pg 718, 2005)

Cullen M. Taniguchi et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Multidisciplinary Sciences

Comparative Study of Injury Models for Studying Muscle Regeneration in Mice

David Hardy et al.

PLOS ONE (2016)

Article Biochemistry & Molecular Biology

Selective control of skeletal muscle differentiation by Akt1

Elizabeth M. Wilson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)