Association of serum uric acid levels with bone mineral density and the presence of osteoporosis in Chinese patients with Parkinson's disease: a cross-sectional study

Article Endocrinology & Metabolism

Association between serum uric acid level and bone mineral density at multiple skeletal sites in middle-aged and elderly men: a cross-sectional study of a healthy population in Taiwan

Zih-Cen Lin et al.

Summary: This study found no association between serum uric acid (sUA) levels and bone mineral density (BMD) at different skeletal sites in middle-aged and elderly men, but a positive association was only found in the normal weight group.

ARCHIVES OF OSTEOPOROSIS (2022)

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Article Immunology

The New 2021 CKD-EPI Equation Without Race in a European Cohort of Renal Transplanted Patients

Pierre Delanaye et al.

Summary: This study compared the predictive performance of the new CKD-EPI equation, classical CKD-EPI equation, and EKFC equation in a French cohort of KTRs. The results showed that the new CKD-EPI equation was less accurate compared to the classical CKD-EPI and EKFC equations. Further validation of the EKFC equation in KTRs with diverse ethnic backgrounds is needed.

TRANSPLANTATION (2022)

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Review Clinical Neurology

Uric Acid in Parkinson's Disease: What Is the Connection?

Fatemeh Seifar et al.

Summary: Numerous studies have found an association between low levels of uric acid (UA) and Parkinson's disease (PD), suggesting that low UA may contribute to oxidative stress and the degeneration of dopamine neurons, leading to the onset and progression of PD symptoms. However, recent research has raised questions about this explanation, proposing that low UA may be a biomarker rather than a causative factor for PD.

MOVEMENT DISORDERS (2022)

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Article Emergency Medicine

Fractures in Parkinson's Disease: injury patterns, hospitalization, and therapeutic aspects

Nils Muehlenfeld et al.

Summary: Fall-related fractures were found to be common and significant complications in PD patients, leading to increased immobility, frequent hospitalization, and immediate surgical care. Fractures of the lower extremities and trunk were the most common in the cohort for this study.

EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY (2021)

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Article Clinical Neurology

Association between freezing of gait and bone mineral density in patients with Parkinson's disease

Seong-Min Choi et al.

Summary: The study found that FOG in PD patients is significantly associated with BMD in the femoral neck area, suggesting that PD patients with FOG should be screened for osteoporosis.

NEUROLOGICAL SCIENCES (2021)

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Article Endocrinology & Metabolism

Serum Uric Acid Level Is Positively Associated With Higher Bone Mineral Density at Multiple Skeletal Sites Among Healthy Qataris

Wisam Nabeel Ibrahim et al.

Summary: The study found a significant association between high uric acid levels and increased bone density among healthy Qatari adults, even after adjusting for multiple confounding factors. However, the association was attenuated with further adjustments, but still remained significant for individuals with high uric acid levels. Additionally, the association between uric acid and bone mineral density was not significant in non-obese, females, young adults, and smokers.

FRONTIERS IN ENDOCRINOLOGY (2021)

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Review Orthopedics

Oxidative Stress and Osteoporosis

Jeff S. Kimball et al.

Summary: Oxidative stress has been implicated as a potential cause of osteoporosis, and a diet rich in antioxidant-containing plant foods along with lifestyle changes may help improve bone density and reduce fracture risk. More research is needed to determine the exact role of antioxidants in preventing and treating osteoporosis.

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2021)

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Article Multidisciplinary Sciences

No association between serum uric acid and lumbar spine bone mineral density in US adult males: a cross sectional study

Xiaoli Li et al.

Summary: The study did not find any association between serum uric acid and lumbar spine bone mineral density in US adult males. More prospective studies are needed to explore the causal relationship between them.

SCIENTIFIC REPORTS (2021)

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Article Neurosciences

Serum Uric Acid Levels and Non-Motor Symptoms in Parkinson's Disease

Daniel J. van Wamelen et al.

JOURNAL OF PARKINSONS DISEASE (2020)

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Review Cell Biology

Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress

Annika Hoehn et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)

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Article Endocrinology & Metabolism

Association between Uric Acid and Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes Mellitus in China: A Cross-Sectional Inpatient Study

Xin Zhao et al.

JOURNAL OF DIABETES RESEARCH (2020)

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Article Medicine, General & Internal

Association of Serum Uric Acid Status With Bone Mineral Density in Adolescents Aged 12-19 Years

Kaiyu Pan et al.

FRONTIERS IN MEDICINE (2020)

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Article Endocrinology & Metabolism

Relationships between serum uric acid concentrations, uric acid lowering medications, and vertebral fracture in community-dwelling elderly Japanese men: Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Cohort Study

Masayuki Iki et al.

BONE (2020)

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Review Urology & Nephrology

The role of uric acid in mineral bone disorders in chronic kidney disease

Baris Afsar et al.

JOURNAL OF NEPHROLOGY (2019)

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Review Clinical Neurology

Parkinson's disease in the Western Pacific Region

Shen-Yang Lim et al.

LANCET NEUROLOGY (2019)

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Article Endocrinology & Metabolism

Association between serum uric acid and bone health in adolescents

F. Karimi et al.

OSTEOPOROSIS INTERNATIONAL (2019)

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Article Geriatrics & Gerontology

Specific higher levels of serum uric acid might have a protective effect on bone mineral density within a Chinese population over 60 years old: a cross-sectional study from northeast China

Feng Chen et al.

CLINICAL INTERVENTIONS IN AGING (2019)

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Review Nutrition & Dietetics

The Paradoxical Role of Uric Acid in Osteoporosis

Kun-Mo Lin et al.

NUTRIENTS (2019)

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Article Endocrinology & Metabolism

Positive association between serum uric acid and bone mineral density in Chinese type 2 diabetes mellitus stratified by gender and BMI

Mingxin Xu et al.

JOURNAL OF BONE AND MINERAL METABOLISM (2018)

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Article Medical Laboratory Technology

Association of serum uric acid with bone mineral density and clinical fractures in Chinese type 2 diabetes mellitus patients: A cross-sectional study

Pijun Yan et al.

CLINICA CHIMICA ACTA (2018)

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Article Clinical Neurology

Altered body composition, sarcopenia, frailty, and their clinico-biological correlates, in Parkinson's disease

Ai Huey Tan et al.

PARKINSONISM & RELATED DISORDERS (2018)

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Article Health Care Sciences & Services

Raised serum uric acid is associated with higher bone mineral density in a cross-sectional study of a healthy Indian population

Neelam Kaushal et al.

THERAPEUTICS AND CLINICAL RISK MANAGEMENT (2018)

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Review Cell Biology

Cellular senescence: Molecular mechanisms and pathogenicity

Wenqiang Wei et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

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Article Chemistry, Multidisciplinary

Association of serum uric acid levels with osteoporosis and bone turnover markers in a Chinese population

Dan-dan Yan et al.

ACTA PHARMACOLOGICA SINICA (2018)

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Article Endocrinology & Metabolism

Uric acid and bone mineral density in postmenopausal osteoporotic women: the link lies within the fat

M. Pirro et al.

OSTEOPOROSIS INTERNATIONAL (2017)

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Article Geriatrics & Gerontology

Serum uric acid is associated with lumbar spine bone mineral density in healthy Chinese males older than 50 years

Jing Xiao et al.

CLINICAL INTERVENTIONS IN AGING (2017)

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Review Multidisciplinary Sciences

Physiological functions and pathogenic potential of uric acid: A review

Rashika El Ridi et al.

JOURNAL OF ADVANCED RESEARCH (2017)

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Review Medicine, General & Internal

Hyperuricemia protects against low bone mineral density, osteoporosis and fractures: a systematic review and meta-analysis

Nicola Veronese et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2016)

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Article Urology & Nephrology

The new Asian modified CKD-EPI equation leads to more accurate GFR estimation in Chinese patients with CKD

Jinghua Wang et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY (2016)

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Article Clinical Neurology

Potential mechanisms for low uric acid in Parkinson disease

Radhika Sampat et al.

JOURNAL OF NEURAL TRANSMISSION (2016)

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Article Clinical Neurology

Biomarkers for Dementia and Mild Cognitive Impairment in Parkinson's Disease

Manuel Delgado-Alvarado et al.

MOVEMENT DISORDERS (2016)

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Article Clinical Neurology

Epidemiology of Parkinson Disease

Andrea Lee et al.

NEUROLOGIC CLINICS (2016)

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Article Clinical Neurology

Risk of fracture amongst patients with Parkinson's disease and other forms of parkinsonism

Isobel Sleeman et al.

PARKINSONISM & RELATED DISORDERS (2016)

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Article Endocrinology & Metabolism

Higher Serum Uric Acid Is Associated with Higher Bone Mineral Density in Chinese Men with Type 2 Diabetes Mellitus

Dian-dian Zhao et al.

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2016)

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Article Biochemistry & Molecular Biology

Uric Acid Promotes Osteogenic Differentiation and Inhibits Adipogenic Differentiation of Human Bone Mesenchymal Stem Cells

Hui-Zhang Li et al.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2015)

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Review Endocrinology & Metabolism

Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases

Danielle A. Callaway et al.

JOURNAL OF BONE AND MINERAL METABOLISM (2015)

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Article Endocrinology & Metabolism

Relationship Between Serum Uric Acid and Bone Mineral Density in the General Population and in Rats With Experimental Hyperuricemia

Dihua Zhang et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2015)

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Article Clinical Neurology

A service development study of the assessment and management of fracture risk in Parkinson's disease

Samuel Shribman et al.

JOURNAL OF NEUROLOGY (2014)

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Article Clinical Neurology

Bone health in Parkinson's disease: a systematic review and meta-analysis

Kelli M. Torsney et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2014)

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Article Endocrinology & Metabolism

Uric acid suppresses 1 alpha hydroxylase in vitro and in vivo

Wei Chen et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2014)

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Article Endocrinology & Metabolism

Association between serum uric acid and lumbar spine bone mineral density in peri- and postmenopausal Japanese women

S. Ishii et al.

OSTEOPOROSIS INTERNATIONAL (2014)

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Review Geriatrics & Gerontology

Parkinson's disease and osteoporosis

Frederiek van den Bos et al.

AGE AND AGEING (2013)

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Article Endocrinology & Metabolism

Renal function and bone mineral density in community-dwelling elderly Japanese men: The Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study

Yuki Fujita et al.

BONE (2013)

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Article Endocrinology & Metabolism

Serum uric acid plays a protective role for bone loss in peri- and postmenopausal women: A longitudinal study

Joanna Makovey et al.

BONE (2013)

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Review Biochemistry & Molecular Biology

Oxidative stress and vascular inflammation in aging

Mariam El Assar et al.

FREE RADICAL BIOLOGY AND MEDICINE (2013)

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Article Biochemistry & Molecular Biology

Uric Acid Secretion from Adipose Tissue and Its Increase in Obesity

Yu Tsushima et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

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Article Endocrinology & Metabolism

Higher serum uric acid is associated with higher bone mass, lower bone turnover, and lower prevalence of vertebral fracture in healthy postmenopausal women

S. H. Ahn et al.

OSTEOPOROSIS INTERNATIONAL (2013)

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Review Neurosciences

Mitochondrial dysfunction and oxidative stress in Parkinson's disease

Sudhakar Raja Subramaniam et al.

PROGRESS IN NEUROBIOLOGY (2013)

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Article Geriatrics & Gerontology

Bone and mineral metabolism in older adults with Parkinson's disease

Suzan Abou-Raya et al.

AGE AND AGEING (2009)

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Review Medical Laboratory Technology

The paradoxical relationship between serum uric acid and cardiovascular disease

Giuseppe Lippi et al.

CLINICA CHIMICA ACTA (2008)

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Article Medicine, General & Internal

Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men

Sachiko Tamba et al.

INTERNAL MEDICINE (2008)

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Article Biochemistry & Molecular Biology

Uric acid: The oxidant-antioxidant paradox

Yuri Y. Sautin et al.

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2008)

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Review Pharmacology & Pharmacy

Uric acid and oxidative stress

GK Glantzounis et al.

CURRENT PHARMACEUTICAL DESIGN (2005)

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Review Neurosciences

Role of oxidative stress and antioxidants in neurodegenerative diseases

AV Rao et al.

NUTRITIONAL NEUROSCIENCE (2002)

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Association of serum uric acid levels with bone mineral density and the presence of osteoporosis in Chinese patients with Parkinson's disease: a cross-sectional study

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