期刊
CHEMICAL COMMUNICATIONS
卷 51, 期 25, 页码 5351-5354出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/C4CC08472A
关键词
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资金
- Academy of Finland [263504, 267497, 273645]
- Biocentrum Helsinki and Emil Aaltonen Foundation
In this communication, we present a nanoscale reactor assembled from tuneable and spatially addressable tubular DNA origami units. We can controllably combine separate origami units equipped with glucose oxidase (GOx) and horseradish peroxidase (HRP), and demonstrate efficient GOx/HRP enzyme cascade reaction inside the tube. The reactor could be utilized as a nanoscale diagnostic tool, and modularity of the proposed system would further enable more complex reactions.
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