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Rheumatoid Arthritis and Cognitive Impairment or Dementia: An Updated Review of Epidemiological Data

JOURNAL OF ALZHEIMERS DISEASE (2023)

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Risk Factors for Dementia in Patients With Incident Rheumatoid Arthritis: A Population-Based Cohort Study

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Summary: This study assessed the risk factors for dementia in patients with rheumatoid arthritis (RA). The findings showed that older age, rheumatoid nodules, hypertension, joint swelling, cardiovascular diseases, and psychological issues were associated with an increased risk of dementia.

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Comparative Risk of Alzheimer Disease and Related Dementia Among Medicare Beneficiaries With Rheumatoid Arthritis Treated With Targeted Disease-Modifying Antirheumatic Agents

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Rheumatoid Arthritis, Cognitive Impairment, and Neuroimaging Biomarkers: Results from the Mayo Clinic Study of Aging

Maria Vassilaki et al.

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JOURNAL OF ALZHEIMERS DISEASE (2022)

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2022 Alzheimer's disease facts and figures

Joseph Gaugler et al.

Summary: This article discusses the impact of Alzheimer's disease on public health, including its incidence, prevalence, mortality and morbidity rates, healthcare costs and caregivers' burden. It also addresses the perspectives of consumers and primary care physicians on mild cognitive impairment (MCI) and the need for improved awareness, diagnosis, and treatment. The article emphasizes the increasing number of individuals living with Alzheimer's and the challenges faced by caregivers and healthcare providers, particularly during the COVID-19 pandemic.

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Common Factors of Alzheimer's Disease and Rheumatoid Arthritis-Pathomechanism and Treatment

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Summary: The accumulation of amyloid plaques can lead to amyloidosis, which plays a significant role in neurodegenerative diseases like Alzheimer's disease, Parkinson's disease, and rheumatoid arthritis. Research is focused on understanding the relationship and cause-effect link between these disorders, as well as exploring innovative therapies for amyloidosis.

MOLECULES (2021)

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Association between dementia and systemic rheumatic disease: A nationwide population-based study

Hyemi Park et al.

Summary: This population-based study in Korea found that systemic lupus erythematosus (SLE) was independently associated with a higher risk of dementia, including Alzheimer's disease (AD) and vascular dementia (VaD). The association was stronger for VaD in SLE patients under 65 years old, suggesting a need for early screening and prevention in this high-risk group.

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Association of cardiovascular disease and traditional cardiovascular risk factors with the incidence of dementia among patients with rheumatoid arthritis

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Summary: The study found that patients with rheumatoid arthritis aged 65 and older who have both cardiovascular disease and cardiovascular risk factors are at increased risk for dementia, but this risk decreases with age. The impact of RA treatment and cardiovascular primary prevention strategies on preventing dementia in RA patients warrants further study.

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Trends in incidence of dementia among patients with rheumatoid arthritis: A population-based cohort study

Vanessa L. Kronzer et al.

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No increased risk of Alzheimer's disease among people with immune-mediated inflammatory diseases: findings from a longitudinal cohort study of US older adults

Michael J. Booth et al.

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Reduced cognitive ability in people with rheumatoid arthritis compared with age-matched healthy controls

James M. Gwinnutt et al.

Summary: The study compared the cognitive ability of people with rheumatoid arthritis (RA) and healthy controls. People with RA showed impairments in memory, verbal fluency, visuospatial functioning, executive function, and emotional recognition compared to healthy controls. Cognitive impairment screening for RA patients may be beneficial for early interventions.

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Article Rheumatology

No association between rheumatoid arthritis and cognitive impairment in a cross-sectional national sample of older US adults

Michael J. Booth et al.

Summary: Through analyzing data from a large national probability sample of older U.S. adults, this study found no association between rheumatoid arthritis (RA) and cognitive impairment (CI).

BMC RHEUMATOLOGY (2021)

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Article Rheumatology

Rheumatoid arthritis and neurodegenerative dementia: a nested case-control study and a follow-up study using a national sample cohort

Chanyang Min et al.

CLINICAL RHEUMATOLOGY (2020)

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Assessment of cognitive function in female rheumatoid arthritis patients: associations with cerebrovascular pathology, depression and anxiety

Csaba Olah et al.

RHEUMATOLOGY INTERNATIONAL (2020)

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Mengshi Zhou et al.

PLOS ONE (2020)

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Corticosteroids and Cognition: A Meta-Analysis

Catherine E. Prado et al.

NEUROPSYCHOLOGY REVIEW (2019)

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Cognitive impairment in patients with rheumatoid arthritis

Bruno Kusznir Vitturi et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2019)

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Rheumatic diseases are associated with a higher risk of dementia: A nation-wide, population-based, case-control study

Kuan-Ting Chen et al.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES (2018)

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Autoimmune rheumatic diseases increase dementia risk in middle-aged patients: A nationwide cohort study

Tzu-Min Lin et al.

PLOS ONE (2018)

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Associations between specific autoimmune diseases and subsequent dementia: retrospective record-linkage cohort study, UK

Clare J. Wotton et al.

JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH (2017)

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DMARD use is associated with a higher risk of dementia in patients with rheumatoid arthritis: A propensity score-matched case control study

Ming-Hsien Chou et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2017)

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Rheumatoid arthritis and risk for Alzheimer's disease: a systematic review and meta-analysis and a Mendelian Randomization study

Stefania Policicchio et al.

SCIENTIFIC REPORTS (2017)

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Treatment for Rheumatoid Arthritis and Risk of Alzheimer's Disease: A Nested Case-Control Analysis

Richard C. Chou et al.

CNS DRUGS (2016)

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Prolong Exposure of NSAID in Patients With RA Will Decrease the Risk of Dementia A Nationwide Population-Based Cohort Study

Kuang-Hsi Chang et al.

MEDICINE (2016)

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Rheumatoid arthritis and the risk of dementia: A systematic review and meta-analysis

Patompong Ungprasert et al.

NEUROLOGY INDIA (2016)

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Rheumatoid Arthritis Was Negatively Associated with Alzheimer's Disease: A Population-Based Case-Control Study

Li-Ting Kao et al.

PLOS ONE (2016)

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Vascular dementia

John T. O'Brien et al.

LANCET (2015)

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Berkson's Bias, Selection Bias, and Missing Data

Daniel Westreich

EPIDEMIOLOGY (2012)

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Midlife Rheumatoid Arthritis Increases the Risk of Cognitive Impairment Two Decades Later: A Population-Based Study

Karin Wallin et al.

JOURNAL OF ALZHEIMERS DISEASE (2012)

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Review Medicine, General & Internal

Rheumatoid arthritis

DM Lee et al.

LANCET (2001)

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