期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 -, 期 -, 页码 -出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.3c03181
关键词
milk oligosaccharides; humanand animal species; qualitative and quantitative level; lactation
This study investigated the changes in oligosaccharides in human and animal milk over lactation. The results showed that human and camel milk had the highest number of common oligosaccharides, and certain oligosaccharides had higher concentrations in human milk compared to other animal species. Additionally, the changes of different oligosaccharides over lactation varied.
The aim of this study was to investigate the changes in human and animal milk oligosaccharides over lactation. In total, 89, 97, 115, and 71 oligosaccharides were identified in human, bovine, goat, and camel milk. The number of common oligosaccharides between camel and human milk was the highest (16 and 17 in transitional and mature milk). With respect to the absolute concentration of eight oligosaccharides (2 '-FL, 3-FL, alpha 3 '-GL, LNT, LNnT, 3 '-SL, 6 '-SL, and DSL), 2 '-FL, 3 '-FL, LNT, and LNnT were much higher in human than three animal species. 3 '-SL had a similar concentration in bovine colostrum (322.2 mu g/mL) and human colostrum (321.0 mu g/mL), followed by goat colostrum (105.1 mu g/mL); however, it had the highest concentration in camel mature milk (304.5 mu g/mL). The ratio of 6 '-SL and 3 '-SL (1.77) in goat colostrum was similar to that in human colostrum (1.68), followed by bovine colostrum (0.13). In terms of changes of eight oligosaccharides over lactation, they all decreased with the increase of lactation in bovine and goat milk; however, alpha 3 '-GL, 2 '-FL, and 3-FL increased in camel species, and LNT increased first and then decreased over lactation in human milk. This study provides a better understanding of the variation of milk oligosaccharides related to lactation and species.
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