期刊
CHEMICAL COMMUNICATIONS
卷 51, 期 59, 页码 11802-11805出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc02995c
关键词
-
资金
- European Research Council through AdG ROCOCO
Linking together an oligourea and an oligoamide foldamer gives rise to a conformationally well-defined structure, despite the different hydrogen-bonding patterns in the two domains, provided the oligomers are ligated amide C terminus to urea N terminus. A powerful screw-sense preference induced at the N terminus of the resulting chimeric structure provides evidence for cooperative conformational interactions within the 'block co-foldamer'.
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