4.7 Article

The Effect of Gene Editing by CRISPR-Cas9 of miR-21 and the Indirect Target MMP9 in Metastatic Prostate Cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Cancer Statistics, 2021

Rebecca L. Siegel et al.

Summary: Every year, the American Cancer Society projects the numbers of new cancer cases and deaths in the United States, with the latest data showing a significant decline in lung cancer mortality, while prostate cancer mortality has plateaued and breast and colorectal cancer mortality have slowed. Improvements in treatment have accelerated progress against lung cancer, leading to a record drop in overall cancer mortality.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Andrology

miR-21 inhibition reverses doxorubicin-resistance and inhibits PC3 human prostate cancer cells proliferation

Weichong Zhao et al.

Summary: The study showed that suppression of miR-21 significantly reduced cell viability of PC3/DOX, downregulated P-gp expression and activity in DOX-resistant cells, and reversed MDR by increasing the intracellular accumulation of DOX in PC3/DOX cells. Additionally, miR-21 repression led to the upregulation of PTEN and subsequently lower expression of P-gp, enhancing the apoptosis rate of PC3/DOX cells. The findings contribute to the understanding of the role of miR-21 in reversing MDR in prostate cancer.

ANDROLOGIA (2021)

Review Cell Biology

Role of noncoding RNA in drug resistance of prostate cancer

Lifeng Ding et al.

Summary: Prostate cancer is a common form of cancer worldwide, and noncoding RNAs play important roles in drug resistance in this disease. Noncoding RNAs, such as miRNAs, lncRNAs, and circRNAs, participate in cellular processes and diseases, and have potential therapeutic applications in prostate cancer.

CELL DEATH & DISEASE (2021)

Article Biochemistry & Molecular Biology

Therapeutic efficacy of modified anti-miR21 in metastatic prostate cancer

Kyungmin Kim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

Review Biochemistry & Molecular Biology

The Impact of Matrix Metalloproteinase-9 on the Sequential Steps of the Metastatic Process

Giovanni Barillari

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Oncology

Next-generation androgen receptor inhibitors in non-metastatic castration-resistant prostate cancer

Pernelle Lavaud et al.

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2020)

Article Biochemistry & Molecular Biology

CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines

Eva Lentsch et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Oncology

CRISPR/Cas9 targeting of GPRC6A suppresses prostate cancer tumorigenesis in a human xenograft model

Ruisong Ye et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)

Article Multidisciplinary Sciences

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Biochemistry & Molecular Biology

A microRNA code for prostate cancer metastasis

D. Bonci et al.

ONCOGENE (2016)

Article Biochemistry & Molecular Biology

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

F. Ann Ran et al.

Article Biochemical Research Methods

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran et al.

NATURE PROTOCOLS (2013)

Article Biotechnology & Applied Microbiology

MMP-9 overexpression due to TIMP-1 and RECK underexpression is associated with prognosis in prostate cancer

Sabrina Thalita Reis et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS (2011)

Article Biochemistry & Molecular Biology

miR-21: an oncomir on strike in prostate cancer

Marco Folini et al.

MOLECULAR CANCER (2010)

Article Biochemistry & Molecular Biology

MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells

Tao Li et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Review Cell Biology

Matrix metalloproteinases and the regulation of tissue remodelling

Andrea Page-McCaw et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)