相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Low-Intensity Pulsed Ultrasound-Mediated Blood-Brain Barrier Opening Increases Anti-Programmed Death-Ligand 1 Delivery and Efficacy in Gl261 Mouse Model
Mohammed H. H. Ahmed et al.
PHARMACEUTICS (2023)
Anti-Amyloid Monoclonal Antibodies are Transformative Treatments that Redefine Alzheimer's Disease Therapeutics
Jeffrey Cummings
DRUGS (2023)
Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy
Xiaoying Chen et al.
NATURE (2023)
Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial
Catherine J. Mummery et al.
NATURE MEDICINE (2023)
Safety Profile of Low-Intensity Pulsed Ultrasound-Induced Blood-Brain Barrier Opening in Non-epileptic Mice and in a Mouse Model of Mesial Temporal Lobe Epilepsy
Bertrand Mathon et al.
ULTRASOUND IN MEDICINE AND BIOLOGY (2023)
Alzheimer's disease drug development pipeline: 2023
Jeffrey Cummings et al.
ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS (2023)
Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients With Early Alzheimer Disease
Stephen Salloway et al.
JAMA NEUROLOGY (2022)
Pilot study of repeated blood-brain barrier disruption in patients with mild Alzheimer's disease with an implantable ultrasound device
Stephane Epelbaum et al.
ALZHEIMERS RESEARCH & THERAPY (2022)
Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease A Randomized Clinical Trial
Edmond Teng et al.
JAMA NEUROLOGY (2022)
Ultrasound-mediated delivery of novel tau-specific monoclonal antibody enhances brain uptake but not therapeutic efficacy
Rinie Bajracharya et al.
JOURNAL OF CONTROLLED RELEASE (2022)
High-clearance anti-amyloid immunotherapies in Alzheimer?s disease. Part 1: Meta-analysis and review of efficacy and safety data, and medico-economical aspects
N. Villain et al.
REVUE NEUROLOGIQUE (2022)
Extensive frontal focused ultrasound mediated blood-brain barrier opening for the treatment of Alzheimer's disease: a proof-of-concept study
So Hee Park et al.
TRANSLATIONAL NEURODEGENERATION (2021)
A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease
Gerhard Leinenga et al.
ALZHEIMERS RESEARCH & THERAPY (2021)
The Applications of Focused Ultrasound (FUS) in Alzheimer's Disease Treatment: A Systematic Review on Both Animal and Human Studies
Xiaodan Liu et al.
AGING AND DISEASE (2021)
Ultrasound-mediated Delivery of Paclitaxel for Glioma: A Comparative Study of Distribution, Toxicity, and Efficacy of Albumin-bound Versus Cremophor Formulations
Daniel Y. Zhang et al.
CLINICAL CANCER RESEARCH (2020)
The behavioural and neuropathologic sexual dimorphism and absence of MIP-3α in tau P301S mouse model of Alzheimer's disease
Yao Sun et al.
JOURNAL OF NEUROINFLAMMATION (2020)
Blood-Brain Barrier and Delivery of Protein and Gene Therapeutics to Brain
William M. Pardridge
FRONTIERS IN AGING NEUROSCIENCE (2020)
Improvement of glymphatic-lymphatic drainage of beta-amyloid by focused ultrasound in Alzheimer's disease model
Youngsun Lee et al.
SCIENTIFIC REPORTS (2020)
Clinically approved IVIg delivered to the hippocampus with focused ultrasound promotes neurogenesis in a model of Alzheimer's disease
Sonam Dubey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Safety and Feasibility of Repeated and Transient Blood-Brain Barrier Disruption by Pulsed Ultrasound in Patients with Recurrent Glioblastoma
Ahmed Idbaih et al.
CLINICAL CANCER RESEARCH (2019)
Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions
Rucha Pandit et al.
THERANOSTICS (2019)
Unilateral Focused Ultrasound-Induced Blood-Brain Barrier Opening Reduces Phosphorylated Tau from The rTg4510 Mouse Model
Maria Eleni Karakatsani et al.
THERANOSTICS (2019)
Principles and approaches for reproducible scoring of tissue stains in research
David K. Meyerholz et al.
LABORATORY INVESTIGATION (2018)
Safety and Efficacy of Scanning Ultrasound Treatment of Aged APP23 Mice
Gerhard Leinenga et al.
FRONTIERS IN NEUROSCIENCE (2018)
Absence of CX3CR1 impairs the internalization of Tau by microglia
Marta Bolos et al.
MOLECULAR NEURODEGENERATION (2017)
QuPath: Open source software for digital pathology image analysis
Peter Bankhead et al.
SCIENTIFIC REPORTS (2017)
Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model
Rebecca M. Nisbet et al.
BRAIN (2017)
Clinical trial of blood-brain barrier disruption by pulsed ultrasound
Alexandre Carpentier et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain
Nicole Maphis et al.
BRAIN (2015)
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
Hirohide Asai et al.
NATURE NEUROSCIENCE (2015)
Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer's disease mouse model
Gerhard Leinenga et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Proteopathic tau seeding predicts tauopathy in vivo
Brandon B. Holmes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Alzheimer Disease in a Mouse Model: MR Imaging-guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior
Alison Burgess et al.
RADIOLOGY (2014)
Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound
Jessica F. Jordao et al.
EXPERIMENTAL NEUROLOGY (2013)
Gantenerumab: A Novel Human Anti-Aβ Antibody Demonstrates Sustained Cerebral Amyloid-β Binding and Elicits Cell-Mediated Removal of Human Amyloid-β
Bernd Bohrmann et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
Peter T. Nelson et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2012)
Antibodies Targeted to the Brain with Image-Guided Focused Ultrasound Reduces Amyloid-β Plaque Load in the TgCRND8 Mouse Model of Alzheimer's Disease
Jessica F. Jordao et al.
PLOS ONE (2010)
MULTI-MODALITY SAFETY ASSESSMENT OF BLOOD-BRAIN BARRIER OPENING USING FOCUSED ULTRASOUND AND DEFINITY MICROBUBBLES: A SHORT-TERM STUDY
Babak Baseri et al.
ULTRASOUND IN MEDICINE AND BIOLOGY (2010)
Transmission and spreading of tauopathy in transgenic mouse brain
Florence Clavaguera et al.
NATURE CELL BIOLOGY (2009)
Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium
Nickolai Sheikov et al.
ULTRASOUND IN MEDICINE AND BIOLOGY (2008)
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
Yasumasa Yoshiyama et al.
NEURON (2007)
Changed conformation of mutant tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of tau-4R/2N transgenic mice
D Terwel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles
N Sheikov et al.
ULTRASOUND IN MEDICINE AND BIOLOGY (2004)
Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits
K Hynynen et al.
RADIOLOGY (2001)